Photo by Cindy Keese

Seneca lake rentals

We found 355 lake rentals — enter your dates for availability

Find spaces that suit your style

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  • More quality time

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  • All the privacy of home

    Enjoy full kitchens, pools, gardens and more

  • More for less

    More space, more privacy, more amenities — more value

Frequently asked questions

Are there any lake house rentals in Seneca?
Choose from 355 lake house rentals in Seneca. Whatever your plans in this thrilling city, Vrbo makes it a breeze to find the right stay where you can enjoy gorgeous natural landscapes.
How much does it cost to stay in a lake house rental in Seneca?
A number of factors will influence the price of a lake house rental in Seneca, such as the size of the property and how long and when you're travelling. Simply enter your holiday dates and any preferences to find a house near the waterfront that fits your style and budget.
When is the best time to book a lakefront holiday rental in Seneca?
Our lake house rentals are idyllic escapes that are perfect for a holiday at almost any time of the year. But June is when the majority of Vrbo guests book these in-demand properties in Seneca. If you also go then, expect average temperatures of between 18ºC (64ºF) and 31ºC (88ºF) in this part of Oconee County.
Where can I book a lake house in Seneca with great views?
Book a lake house rental in Seneca and you'll be waking up to stunning vistas. Some of our more popular rental houses here feature views of historic areas.
Can I book a lakeside cabin or lodge in Seneca?
For a getaway that combines outdoor adventures with beautiful scenery, nothing beats our lakeside cabins or lodges in Seneca. Vrbo's filters will help you find your dream accommodation. Narrow your search by property, location, amenities and more. Eager to go fishing, boating or try some other lake-related pursuits? Choose the "Nearby activities" filter.
What are the top things to do in Seneca?
Get your Seneca getaway off to a flying start by heading to top-rated sights like Lake Keowee, Memorial Stadium and South Carolina Botanical Gardens. Stay in a Vrbo lake house rental and enjoy time with the family amid glorious scenery.
Why should I book my lake house rental with Vrbo?
Booking your lake house rental with Vrbo means you'll have the entire property to yourselves — your own private retreat by the water's edge, with no distractions or interruptions from anybody else. What's more, our flexible payment and cancellation policies allow you to amend your plans if you need to. Plus, with our One Key™ loyalty programme, you can earn and use OneKeyCash™* on eligible bookings on Vrbo. *OneKeyCash disclaimer - OneKeyCash is not redeemable for cash and can only be used on Vrbo.

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