
Holiday rentals near Mayo Clinic Scottsdale
We found 3,799 holiday rentals — enter your dates for availability
Scroll through and discover holiday rentals close to Mayo Clinic Scottsdale that are perfect for your trip. Whether you're going on holiday with family or friends, holiday homes have the amenities that you expect for your stay, which might include a garden and Wi-Fi. You're sure to find a property to rent that has what everyone needs, including places that are non-smoking or accessible.
Holiday rentals with weekly discounts - Mayo Clinic Scottsdale
Showing deals for:14 Nov - 21 Nov
Image gallery for Fountain View, Heated Pool Included & A Family Retreat

1010 out of 10 rating
Exceptional
(11 reviews)
Fountain View, Heated Pool Included & A Family Retreat
Fountain Hills, AZ
8% off
Price is £5,152
£5,152
£736 per night
includes taxes & fees
Image gallery for 5BR Luxury Stay: King Beds, Hot Tub, Games, Kids' Play Area & Private Pool

1010 out of 10 rating
Exceptional
(5 reviews)
5BR Luxury Stay: King Beds, Hot Tub, Games, Kids' Play Area & Private Pool
Scottsdale, AZ
12% off
Price is £5,243
£5,243
£749 per night
includes taxes & fees
Image gallery for Desert Luxury Retreat| Pool + Hot Tub | Dark Sky

9.89.8 out of 10 rating
Exceptional
(6 reviews)
Desert Luxury Retreat| Pool + Hot Tub | Dark Sky
Fountain Hills, AZ
7% off
Price is £3,083
£3,083
£440 per night
includes taxes & fees
Image gallery for BIGGEST BEST MANSION In NE Scottsdale Area- VIEWS, Infinity Pool, MOVIE THEATER!

1010 out of 10 rating
Exceptional
(12 reviews)
BIGGEST BEST MANSION In NE Scottsdale Area- VIEWS, Infinity Pool, MOVIE THEATER!
Fountain Hills, AZ
8% off
Price is £20,371
£20,371
£2,910 per night
includes taxes & fees
Image gallery for Old Town Casa - Sip Splash Sun

1010 out of 10 rating
Exceptional
(5 reviews)
Old Town Casa - Sip Splash Sun
Scottsdale, AZ
8% off
Price is £2,222
£2,222
£317 per night
includes taxes & fees
Image gallery for Spacious Scottsdale resort style home with pool and indoor/outdoor games

1010 out of 10 rating
Exceptional
(24 reviews)
Spacious Scottsdale resort style home with pool and indoor/outdoor games
Scottsdale, AZ
7% off
Price is £4,786
£4,786
£684 per night
includes taxes & fees
Image gallery for Winter getaway, come escape with a pool!

1010 out of 10 rating
Exceptional
(21 reviews)
Winter getaway, come escape with a pool!
Fountain Hills, AZ
7% off
Price is £1,556
£1,556
£222 per night
includes taxes & fees
Image gallery for Entrepreneur's Enclave Private Pickleball w/ Heated Pool & Hot Tub

1010 out of 10 rating
Exceptional
(64 reviews)
Entrepreneur's Enclave Private Pickleball w/ Heated Pool & Hot Tub
Scottsdale, AZ
5% off
Price is £3,899
£3,899
£557 per night
includes taxes & fees
Image gallery for Luxury Home/Heated Pool/Theater/ Putting Green AZ

1010 out of 10 rating
Exceptional
(13 reviews)
Luxury Home/Heated Pool/Theater/ Putting Green AZ
Mesa, AZ
7% off
Price is £3,432
£3,432
£490 per night
includes taxes & fees
Image gallery for Private guest house near TPC Golf, Car Shows, Spring Training, and hiking trails

1010 out of 10 rating
Exceptional
(49 reviews)
Private guest house near TPC Golf, Car Shows, Spring Training, and hiking trails
Scottsdale, AZ
8% off
Price is £1,215
£1,215
£174 per night
includes taxes & fees
Image gallery for NEW Stylish Retreat near Old Town, Pool, FREE Hot Tub, Pet-Friendly!

1010 out of 10 rating
Exceptional
(14 reviews)
NEW Stylish Retreat near Old Town, Pool, FREE Hot Tub, Pet-Friendly!
Scottsdale, AZ
8% off
Price is £2,463
£2,463
£352 per night
includes taxes & fees
Image gallery for #SuiteHomeScottsdale: Your SPRING TRAINING BASECAMP in Old Town, Scottsdale!

9.89.8 out of 10 rating
Exceptional
(31 reviews)
#SuiteHomeScottsdale: Your SPRING TRAINING BASECAMP in Old Town, Scottsdale!
Scottsdale, AZ
7% off
Price is £2,168
£2,168
£310 per night
includes taxes & fees
Image gallery for Gorgeous 5 BR Oasis, Gated Pool, Putting Green, Fire Pit- perfect for families!

9.89.8 out of 10 rating
Exceptional
(67 reviews)
Gorgeous 5 BR Oasis, Gated Pool, Putting Green, Fire Pit- perfect for families!
Scottsdale, AZ
8% off
Price is £4,014
£4,014
£573 per night
includes taxes & fees
Image gallery for Diving Pool, Family Friendly & Pet Friendly @Cozy Mesa home close to everything!

1010 out of 10 rating
Exceptional
(31 reviews)
Diving Pool, Family Friendly & Pet Friendly @Cozy Mesa home close to everything!
Mesa, AZ
7% off
Price is £1,770
£1,770
£253 per night
includes taxes & fees
Image gallery for Heated Pool, Lavish Yard! - The Desert Wanderer

9.69.6 out of 10 rating
Exceptional
(22 reviews)
Heated Pool, Lavish Yard! - The Desert Wanderer
Scottsdale, AZ
7% off
Price is £2,935
£2,935
£419 per night
includes taxes & fees
Image gallery for Old Town Scottsdale Home with optional Heated Pool, Waterfalls, & Pool Table !

9.09.0 out of 10 rating
Wonderful
(39 reviews)
Old Town Scottsdale Home with optional Heated Pool, Waterfalls, & Pool Table !
Scottsdale, AZ
7% off
Price is £2,002
£2,002
£286 per night
includes taxes & fees
Image gallery for Spacious Scottsdale home with resort yard

1010 out of 10 rating
Exceptional
(22 reviews)
Spacious Scottsdale home with resort yard
Scottsdale, AZ
8% off
Price is £2,645
£2,645
£378 per night
includes taxes & fees
Image gallery for Glamorous Renovated Desert Oasis, Heated Pool, Tub

8.68.6 out of 10 rating
Excellent
(7 reviews)
Glamorous Renovated Desert Oasis, Heated Pool, Tub
Scottsdale, AZ
19% off
Price is £3,040
£3,040
£434 per night
includes taxes & fees
Image gallery for Old Town Saguaro - Pool - Fire Pit- Heart of Old Town

8.88.8 out of 10 rating
Excellent
(40 reviews)
Old Town Saguaro - Pool - Fire Pit- Heart of Old Town
Scottsdale, AZ
8% off
Price is £4,858
£4,858
£694 per night
includes taxes & fees
Image gallery for Stylish First-Floor Condo w/ Pool, Gym, Parking, King Bed & Trails + Pickleball

9.89.8 out of 10 rating
Exceptional
(19 reviews)
Stylish First-Floor Condo w/ Pool, Gym, Parking, King Bed & Trails + Pickleball
Scottsdale, AZ
8% off
Price is £1,560
£1,560
£223 per night
includes taxes & fees
Image gallery for Luxury Single Story Home w/ Pool House, Heated Pool/Spa, Outdoor Living, Fire Pit, Garage Parking!

1010 out of 10 rating
Exceptional
(8 reviews)
Luxury Single Story Home w/ Pool House, Heated Pool/Spa, Outdoor Living, Fire Pit, Garage Parking!
Scottsdale, AZ
7% off
Price is £5,502
£5,502
£786 per night
includes taxes & fees
Image gallery for Solace - Community Pool & Gym -Walk to Restaurants

9.69.6 out of 10 rating
Exceptional
(7 reviews)
Solace - Community Pool & Gym -Walk to Restaurants
Scottsdale, AZ
7% off
Price is £1,553
£1,553
£222 per night
includes taxes & fees
Image gallery for OLD TOWN- POOL- GAMES- PERFECT LOCATION

9.89.8 out of 10 rating
Exceptional
(29 reviews)
OLD TOWN- POOL- GAMES- PERFECT LOCATION
Scottsdale, AZ
8% off
Price is £2,034
£2,034
£291 per night
includes taxes & fees
Image gallery for 2025 VRBO Property of the Year: Scottsdale Luxury Estate: Pool, Spa & Pickleball

1010 out of 10 rating
Exceptional
(61 reviews)
2025 VRBO Property of the Year: Scottsdale Luxury Estate: Pool, Spa & Pickleball
Paradise Valley, AZ
8% off
Price is £10,463
£10,463
£1,495 per night
includes taxes & fees
Find spaces that suit your style
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Find the best place to stay - Mayo Clinic Scottsdale
Ground Floor Poolside Condo! Mayo Clinic Shea Super Close!
Sleeps 4 · 2 bedrooms · 2 bathrooms
9.69.6 out of 10
Exceptionalexceptional
22 reviews(22 reviews)
Luxe Scottsdale Condo - Newly Refurbished Ground Floor Unit!
Sleeps 4 · 2 bedrooms · 2 bathrooms
Clean & Bright 2BR/2BA Scottsdale Vacation Rental - Your Perfect Getaway!
Sleeps 4 · 2 bedrooms · 2 bathrooms
1010 out of 10
Exceptionalexceptional
80 reviews(80 reviews)
Your Perfect Scottsdale Home Base Near Mayo Clinic Campus! Free Shuttle Service!
Sleeps 2 · 1 bedroom · 1 bathroom
9.69.6 out of 10
Exceptionalexceptional
7 reviews(7 reviews)
Luxury designer condo!
Sleeps 6 · 1 bedroom · 2 bathrooms
9.69.6 out of 10
Exceptionalexceptional
23 reviews(23 reviews)
Meridian CondoResorts
Sleeps 13 · 6 bedrooms
8.68.6 out of 10
Excellentexcellent
854 reviews(854 reviews)
Top rated rentals - Mayo Clinic Scottsdale
Firerock point stay
1010 out of 10
Exceptionalexceptional
57 reviews(57 reviews)
This property was amazing, it had everything we needed for our stay with plenty of room. It was also very private with spectacular views.
penny l.
Stayed May 2023
Fantastic time - everything perfect
1010 out of 10
Exceptionalexceptional
138 reviews(138 reviews)
We had a great time at this property. It was just as described and the location was better than we had hoped. Communication with the hosts was excellent, the6 could not have responded any quicker than they did. We had one minor issue, which was resolved very quickly. Overall, this property was perfect for our golf trip and ideal for a few nights out
Ian H.
Stayed Nov 2022
- Peace of mindOur Book with Confidence Guarantee gives you 24/7 support
- More quality timeFrom booking to staying, the whole process is simple and enjoyable
- All the privacy of homeEnjoy full kitchens, pools, gardens and more
- More for lessMore space, more privacy, more amenities — more value