Big Pine Key villas

We found 3 villas — enter your dates for availability

Find spaces that suit your style

  • Peace of mind

    Our Book with Confidence Guarantee gives you 24/7 support

  • More quality time

    From booking to staying, the whole process is simple and enjoyable

  • All the privacy of home

    Enjoy full kitchens, pools, gardens and more

  • More for less

    More space, more privacy, more amenities — more value

Frequently asked questions

How much does it cost to stay in a villa rental in Big Pine Key?
Larger villa rentals or those with fancy amenities often cost more, so choose something a little more basic if you want to save money. Being near major attractions or in a breathtaking location can also influence how much you'll pay. You can look for a villa rental in Big Pine Key that fits your budget by entering your maximum total or nightly price.
Where can I rent a Big Pine Key villa with great views?
If you're looking for a good way to kick back after a thrilling day, find yourself a spot and take in the impressive vistas from your villa rental. Use Vrbo's filters to refine your search for options that'll add a touch of scenic wonder to your Big Pine Key getaway. Our "Location" filter is an excellent place to begin.
Can I book a luxury villa in Big Pine Key?
Take your holiday to new heights with one of our villa rentals in Big Pine Key. Offering premium conveniences such as fully-equipped kitchens, advanced entertainment systems and plush furnishings, you and your guests will enjoy a VIP experience. Use Vrbo's filter tool to find villas with exclusive perks like private pools and outdoor space for that extra layer of opulence and luxury.
What are the top things to do in Big Pine Key?
One of the first things to do after locking in your villa rental is to fill your schedule with fun activities. There's plenty of them in Big Pine Key, with top-rated family-friendly attractions including Bahia Honda State Park, Calusa Beach and National Key Deer Refuge Visitor Centre.
Why should I book my villa holiday with Vrbo?
Book your villa rental with Vrbo and experience more privacy and space compared to traditional hotel accommodation. These types of stays offer that home-away-from-home vibe. One of the best benefits? You'll never have to share your space, whether you spend your holiday in a villa or somewhere a little fancier, like an estate or a castle. And if you're a member of our One Key™ loyalty programme, you can collect and redeem OneKeyCash™* on eligible bookings on Vrbo. *OneKeyCash disclaimer - OneKeyCash is not redeemable for cash and can only be used on Vrbo.