Discover a selection of 500 vacation rentals in St. Louis that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including swimming pools and private pools. Prices start at $95 per night, and houses and cabins are popular options for a stay in St. Louis. Either way, you'll find a rental for everyone's needs.
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Top rated rentals — St. Louis
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Destination guide

St. Louis opens the gate to the West

Step onto the St. Louis side of the Mississippi River and you’ll immediately know you're someplace else. Somewhere big on skies, big on space, and big on promise. Even before the silver arc of the Gateway Arch makes that change real, it's obvious you've said goodbye to the jaded East and hello to the can-do West. Visitors booking St. Louis vacation rentals are here, in part, to be electrified by that change in outlook, but also to revel in city of delightful diversity, top-ranked museums, paddleboat extravaganzas, and melt-in-the-mouth BBQ ribs.

Things to do

Keeping culture playful in St. Louis

St. Louis doesn't do dull when it comes to culture. Step into the City Museum and you'll think you're in an architectural playground. Packed with mazes, chutes, and mind games, it'll flip your idea of what a museum is all about. The Cathedral Basilica of St. Louis blows the mind too, with its stunning series of mosaics. Forest Park keeps your body busy with its tree-lined walks, ice rink, and outdoor boogie fests. Top it all off with a toast to St. Louis' beer scene, which runs from cult craft outfits to the larger local brewers.

Activities

St. Louis—paddles, music, and grills

The Mississippi is what's made St. Louis magnificent. And the view from this mighty river's impossible to beat. So, pile onto a paddleboat to see the glittering Gateway Arch at its river-facing best. Unknown to many, music—from ragtime to blues—has made its mark on this Missouri city. Be sure to check out the clubs of the Delmar Loop to find out more about the musical heritage of the city. And if you're wanting to dip into the city's famed smokehouse heritage, but don't know which St. Louis bar ‘n grill to hit, try a culinary tour led by a local grill gourmet.

Weather

St. Louis—sweetest in fall

This city doesn't just sit on the fault line between the American East and West—St. Louis is also in the middle of a climate conundrum. Here, temperatures see-saw wildly with the passing of the seasons. That makes the shoulder months of spring and fall the best for visitors looking for comfort from their St. Louis vacation rentals. Spring is beautiful, but can be a little unsettled. September and October are especially good for the St. Louis bound, though. It's less showery and visitor numbers dwindle.

Natural features

The wild things in St. Louis

With not one but two mighty rivers running through St. Louis (the Missouri River and the Mississippi River meet here, in case you're wondering), there's no shortage of dramatic natural spectacle here. These 2 rivers form great glittering sweeps that add extra color to the city's sunsets. Wildlife from across the globe can be found in St. Louis Zoo, of course. But the city itself has wild moments of its own, too. Those leaving early from their St. Louis vacation rentals might be lucky enough to spot coyotes, white-tailed deer, or even armadillos ambling the back streets.

How to get there

Transportation options to and around St. Louis

Fly into St. Louis, MO (STL-Lambert-St. Louis Intl.), the closest airport, located 11.7 mi (18.8 km) from the city center. If you're unable to find a flight that fits your schedule, you might consider flying into St. Louis, MO (SUS-Spirit of St. Louis), which is 23.8 mi (38.4 km) away.

If you'd rather travel by train, the main station is St. Louis Gateway Station. It's easy to get around St. Louis by catching a ride on the metro at 8th and Pine Station, Stadium Station or Convention Center Station.

How many vacation rentals are available around St. Louis?

Our 2021 property listings offer a large selection of 641 vacation rentals around St. Louis. From 215 house rentals to 4 cabin rentals, find a unique house rental for you to enjoy a memorable holiday or a weekend with your family and friends.

Explore destinations around St. Louis

Central West End
167 vacation rentals
Downtown St. Louis
399 vacation rentals
Soulard
85 vacation rentals
Downtown West
139 vacation rentals
Southwest Garden
57 vacation rentals
Tower Grove East
83 vacation rentals
Tower Grove South
75 vacation rentals
Benton Park
86 vacation rentals
DeBaliviere Place
70 vacation rentals
Near Southside
62 vacation rentals
Shaw
83 vacation rentals
Lafayette Square
76 vacation rentals
LaSalle Park
60 vacation rentals
Lindenwood Park
19 vacation rentals
Clifton Heights
20 vacation rentals
The Gate
70 vacation rentals
Grand Center
29 vacation rentals
Clayton-Tamm
27 vacation rentals
Compton Heights
64 vacation rentals
Northampton
27 vacation rentals