Discover a selection of 119 vacation rentals in Mesquite that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including swimming pools and private pools. Prices start at $89 per night, and houses and condos are popular options for a stay in Mesquite. Either way, you'll find a rental for everyone's needs.
Top rated rentals — Mesquite
Destination guide

“Pioneering with Pride” in Mesquite

A great love of the land in Mesquite is from the legacy of the pioneers who first settled here. There are year-round golf courses and deluxe resort casinos as well as cattle farms, dairies and alfalfa cultivation. The wide, open, blue sky over the expansive desert below is the perfect plunge for skydivers and pilots alike. Full of opportunities for family fun, a rich pioneer heritage has produced a peaceful sanctuary featuring family-friendly Mesquite vacation rentals that cover the gamut of condos, houses and more.

Things to do

Experience the rich pioneer heritage in Mesquite

Learn more about the area’s history at the Virgin Valley Heritage Museum, which houses artifacts and photos, memorabilia and research materials donated by families of the early settlers. See how Mesquite became what it is today through the eyes of the people who transformed it. Pop next door to visit the Mesquite Fine Arts Gallery, featuring local and guest artists with a more modern vision. At the Lost City Museum, travel back to ancient times to experience the life of the early Pueblo Indians through one of the most complete collections of artifacts in the Southwestern United States.


Go outside and play in Mesquite

Family-friendly hikes of all levels, mountain bike trails, and nature tours are yours for the taking. Venture out on a camel safari or take off on a segway tour to view the magnificent mesas up close. A short distance from many Mesquite vacation rentals, play a round or two at your choice of 5 lush golf courses in the Virgin Mountain foothills. Or, if you prefer to play indoors, try your hand at a game of chance in any one of nine resort casinos. Experience the lights and music of cosmic bowling or get your heart pumping with a variety of sports at the recreation center.


Soak up the sun in Mesquite

With over 300 days of sunshine a year, Mesquite enjoys a warm desert climate. Verging on daytime highs of 100 F, June through September, evenings cool down to the 60s and 70s providing a perfect night’s sleep at Mesquite vacation rentals. Some like it hot in the summer and others prefer the cool fall or winter, with daytime temperatures ranging from 60-80 F and 60-70 F, respectively. Evenings are always refreshing here and freezing temperatures are a rarity, though the thermometer may take a slight dip below 32 F during some nights in January.

Natural features

Happiness in the high desert of Mesquite

At home on the range, Mesquite cattle are a testament to the hard-fought battle pioneers won to keep this high desert hamlet pristine and habitable. Ideally located in a state known for its scenic landscapes of hidden canyons and unique colored rock formations, Mesquite is within easy reach of the Valley of Fire State Park, Cedar Breaks National Monument, Cathedral Gorge and Bryce Canyon National Park. Boasting the stuff of a photographer’s dream, all of these natural attractions were sculpted by Mother Nature herself and are home to an extensive variety of thriving flora and fauna.

How many vacation rentals are available around Mesquite?

Our 2021 property listings offer a large selection of 119 vacation rentals around Mesquite. From 32 house rentals to 87 condo and apartment rentals, find a unique house rental for you to enjoy a memorable holiday or a weekend with your family and friends.