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Otay Mesa West holiday lettings
We found 12 holiday rentals — enter your dates for availability
Discover a selection of holiday rentals in Otay Mesa West that are perfect for your trip. Whether you're going on holiday with family or friends, holiday rentals have the amenities that you expect for your stay, including Wi-Fi and parking. You'll be sure to find a property to rent that has what everyone needs, including options that are accessible or non-smoking.
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Find the best place to stay - Otay Mesa West

Luxury San Diego Home w/ Pool, Spa & Views!
Sleeps 12 · 5 bedrooms · 3 bathrooms
9.8 out of 10
exceptional
(24 reviews)
Top rated rentals - Otay Mesa West

The best property
9.8 out of 10
exceptional
(188 reviews)
We have travelled throughout the US and have frequently stayed in rental properties, this one is truly outstanding. It has everything you could possibly wish for. Patrick was an excellent host and the pool, garden and view are just fabulous. My only criticism would be that the sunbeds are getting tired, and the location is not ideal if you want a local bar or nightlife.
Neil D.
Stayed May 2025
- Peace of mindOur Book with Confidence Guarantee gives you 24/7 support
- More quality timeFrom booking to staying, the whole process is simple and enjoyable
- All the privacy of homeEnjoy full kitchens, pools, gardens and more
- More for lessMore space, more privacy, more amenities — more value