Santee vacation rentals

We found 202 vacation rentals — enter your dates for availability

Discover a selection of 8 homes and other vacation rentals in Santee that are perfect for your trip. Vacation homes offer the best amenities for you and your friends, family, or even pets, such as a hot tub and a washer and dryer. At the end of the day, you'll be sure to find a rental for everyone's needs, including accessible or non-smoking choices.

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Find out more about Santee

Why visit Santee

  • Outdoor Adventures: Santee is ideal for hiking, fishing, and water sports in its scenic national parks and serene lakes.
  • Romantic Getaways: Couples can enjoy a peaceful retreat with beautiful landscapes and cozy accommodations.
  • Charming Neighborhoods: Explore the friendly atmosphere and unique charm of Santee's local neighborhoods.
  • Vacation Rentals: A variety of accommodation options, including private homes and cabins, cater to all preferences.
  • Nearby Beaches: Enjoy sandy beaches just a short drive away, perfect for relaxation and family outings.

Popular types of accommodation in Santee

If you're planning a getaway to Santee, you’ll find a variety of fantastic vacation rentals to suit your needs. The most popular options include houses, cozy cabins, and charming cottages. Whether you’re looking for house rentals, Santee apartments, or bedroom rentals, we have it all. Plus, many accommodations offer laundry facilities to make your stay even more convenient. Explore Santee's options for an unforgettable vacation experience.

  • Houses: The top choice for travelers in Santee, these homes offer spacious accommodations perfect for families or groups seeking comfort and privacy.
  • Cabins: A favorite for nature enthusiasts, these rustic retreats provide a cozy escape immersed in the beauty of the outdoors.
  • Cottages: These charming abodes are ideal for a quaint and intimate getaway, perfect for couples or solo travelers.
  • Condos: A modern option that combines convenience with comfort, ideal for those wanting easy access to local attractions.
  • Apartments: Great for budget-conscious travelers, these rentals offer a home-like atmosphere with essential amenities.**

Top attractions in and around Santee

Santee, South Carolina, is a perfect destination for outdoor enthusiasts and couples seeking a romantic getaway. With its stunning national parks, serene lakes, and picturesque islands, visitors can enjoy a variety of scenic experiences. Whether you're looking to hike, relax by the water, or explore the natural beauty, Santee offers a delightful mix of attractions that cater to those who appreciate the great outdoors.

  • Santee State Park: Nestled within Santee, this national park offers thrilling outdoor adventures amidst stunning natural scenery. Enjoy hiking, fishing, and camping while immersing yourself in the great outdoors.
  • Santee Indian Mound and Fort Watson Site: Located 4 miles from Santee, this cultural landmark provides a glimpse into the area's rich history, showcasing Native American heritage and the remnants of an early fort.
  • Taw Caw Creek: Just 9 miles away, this picturesque lake features sandy beaches and romantic scenery, perfect for a day of relaxation, picnicking, or enjoying water activities.

Things to do recommended for couples

Discover romance in Santee, South Carolina, with a cozy picnic by Lake Marion or a scenic boat ride at sunset. Explore the lush landscapes together at Santee State Park, and savor a candlelit dinner at a local eatery for an unforgettable evening.

Things to do recommended for families

Your family will love exploring the Santee National Wildlife Refuge, just 4 miles from town, offering serene nature walks and birdwatching. Additionally, Taw Caw Creek Park, located 9 miles away, provides a perfect spot for relaxation and outdoor fun, making it a great day out for everyone.

Things to do recommended for groups

Experience the outdoors with your group at Santee Cooper Country Club and Santee National Golf Club, both offering fantastic golfing opportunities. For a short drive, head to Wyboo Golf Club, about 16 miles away, to enjoy more scenic courses and a great atmosphere.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

What do I need to keep in mind when booking a vacation in Santee

When traveling with a group, family, pets, or planning an extended stay, it's important to filter your options based on what matters most to you. Here are some helpful Vrbo booking tips to guide you.

  • Traveling to Santee with a group: Think about how many bedrooms you'll require, along with features like a fully equipped kitchen or outdoor areas for group gatherings. Luckily, you can easily narrow down your options for these and many other preferences on Vrbo.
  • Traveling to Santee with young kids: Traveling with young kids can be quite a challenge. It's important to prioritize their comfort and safety, along with having access to age-appropriate amenities, like a private swimming pool. Additionally, it's wise to think about how close you are to family-friendly attractions.
  • Taking your pets with you to Santee: For many families, a trip isn’t truly fulfilling without their furry companions. If this resonates with you, explore Vrbo listings that welcome pets. Most pet-friendly properties come equipped with feeding bowls and cozy beds, ensuring that every member of the family feels comfortable and at home.
  • Planning for a long term stay visiting Santee: If you're searching for vacation rentals with special offers for stays of a month or more, you've come to the right spot. By using the appropriate filters, you can effortlessly discover and save on monthly rentals. Don't forget to include options like a parking space, a well-equipped kitchen, or a private pool in your search criteria as well.

Where to stay near Santee

Santee, South Carolina, is a hidden gem perfect for outdoor enthusiasts and romantic getaways. With its scenic beauty and friendly atmosphere, visitors can explore charming neighborhoods and enjoy sandy beaches nearby. Whether you're looking for family-friendly excursions or a peaceful retreat, Santee offers a delightful mix of experiences. Don't miss the opportunity to immerse yourself in the local vibe and discover the area's unique charm during your vacation.

  • Summerton: Summerton is a charming city located 11 miles from Santee, offering a delightful escape for outdoor enthusiasts and romantics alike. The scenic landscapes are perfect for leisurely strolls or picnics, while the nearby recreational areas invite activities like golf. Visitors can enjoy the serene beauty of local lakes and the lush surroundings of national and state parks. Whether you're exploring the tranquil waters or taking in the breathtaking scenery, Summerton promises a perfect backdrop for relaxation and adventure.
  • Vance: Just 5 miles away from Santee, Vance is a hidden gem that beckons travelers with its picturesque outdoor settings and romantic ambiance. The city is surrounded by natural beauty, featuring lakes and an array of recreational areas perfect for golf and leisurely activities. Vance is also close to a national state park and an island, offering opportunities for exploration and relaxation. Enjoy a day spent surrounded by nature or indulge in a round of golf, making Vance an ideal destination for a peaceful getaway.
  • Elloree: Located 6 miles from Santee, Elloree is a wonderful city that captivates visitors with its scenic beauty and outdoor adventures. The area boasts excellent golf courses and recreational spaces, making it a haven for sports enthusiasts. Nature lovers will appreciate the nearby lakes and national parks, where stunning landscapes and diverse wildlife await. With its romantic setting and opportunities for relaxation, Elloree is a fantastic choice for those looking to immerse themselves in the tranquility of South Carolina's countryside.

Best time to go to Santee

If you're planning a trip to Santee, it's a good idea to check both the weather and property rates. The warmest month is July. Peak season runs in March to April and July, while off-peak times, like October to December tend to have fewer bookings and better deals.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January47.3°F (8.5°C)Light RainMostly SunnyAverageSlightly Low
February51.4°F (10.8°C)Light RainMostly SunnyAverageSlightly Low
March56.8°F (13.8°C)Light RainMostly SunnySlightly HighSlightly Low
April64.4°F (18.0°C)Light RainMostly SunnySlightly HighAverage
May72.0°F (22.2°C)Light RainMostly SunnyAverageAverage
June78.6°F (25.9°C)Light RainMostly SunnyAverageSlightly High
July81.5°F (27.5°C)Light RainMostly SunnySlightly HighSlightly High
August79.9°F (26.6°C)Light RainMostly SunnyAverageSlightly High
September75.4°F (24.1°C)Light RainMostly SunnyAverageAverage
October66.4°F (19.1°C)Light RainMostly SunnySlightly LowAverage
November56.1°F (13.4°C)Light RainMostly SunnySlightly LowAverage
December51.3°F (10.7°C)Light RainMostly SunnySlightly LowAverage

Booking with Vrbo is simple

Are you hoping to save money on your upcoming journey? Being flexible with your travel dates can make a big difference, as prices often fluctuate. Additionally, booking a longer stay can lead to substantial savings. To discover a Vrbo property that suits your budget, feel free to use our filters to narrow down your options by price, location, and type of vacation rental. We're here to help you find the perfect getaway.

Vrbo Trips: Planning made easy

Vrbo’s Trip Board offers a user-friendly platform for planning your travel adventures. You can easily create new trips, resume your planning from where you left off, or organize your existing plans all in one place. Your saved or booked properties will be neatly organized under categories such as Potential, Upcoming, or Current Trips. To begin exploring Trip Boards, simply visit: https://www.vrbo.com/trips.

**Based on Vrbo properties bookings.

The friendly area of Santee awaits your stay

The lake and surrounding scenery provide a peaceful ambiance to your vacation home in Santee. Travelers to this welcoming city praise the restaurants, golfing and fishing. Whether you're planning a family vacation, friends trip or romantic retreat, Vrbo has a great selection of vacation homes. Many rentals come with a full kitchen and separate dining area, perfect if you need a space for entertaining.

Activities and attractions in Santee

Do you want to discover attractions to visit while you're in the area? Venture out of your cozy vacation rental and experience everything that makes Santee a fun spot to vacation. Here are some of the top attractions to put on your list, all within 30 miles (48.2 km) of the city center:

  • Santee Cooper Country Club (0.6 mi / 1 km)
  • Santee National Golf Club (0.8 mi / 1.4 km)
  • Wyboo Golf Club (16.3 mi / 26.3 km)
  • St. George Country Club (22.6 mi / 36.4 km)

Exploring the natural features in Santee

Whether you're looking for adventure or just want to appreciate the scenery, Santee is a great place to spend some time outside. These are some of the area's most enchanting natural features, all within 30 miles (48.2 km) of the city center:

  • Lake Marion (7.9 mi / 12.7 km)
  • Taw Caw Creek (8.5 mi / 13.7 km)
  • Edisto Memorial Gardens (22.7 mi / 36.5 km)
  • Santee National Wildlife Refuge (4.4 mi / 7 km)
  • Pine Island (7.4 mi / 12 km)
  • Goat Island (9.4 mi / 15.1 km)

Transportation to and around Santee

The nearest airport is in Columbia Metropolitan Airport (CAE), located 49 mi (78.8 km) from the city center.

Frequently asked questions

What is the best area to stay in Santee, South Carolina, United States of America when booking a vacation rental?
When considering a vacation rental in Santee, South Carolina, the area surrounding Lake Marion is particularly appealing. This picturesque neighborhood offers a serene atmosphere and easy access to outdoor activities, making it ideal for those looking to enjoy nature. Visitors can experience the beauty of the lake through fishing, boating, and hiking in the nearby Santee State Park, which is known for its scenic trails and abundant wildlife.

Another attractive option is the area near the Santee National Golf Club, great for golf enthusiasts. This neighborhood not only provides convenient access to the course but also boasts charming dining options and local shops.
How much does it cost to rent a vacation home in Santee?
Prices for vacation rentals in Santee vary based on factors like travel dates, length of stay, accommodation type, and location. Simply enter your trip details to explore a wide range of options—whether you're traveling solo, as a couple, with family, or in a group. Vrbo offers something for every taste and budget, from affordable rentals in Santee to more spacious homes. To get the best value, book early and take advantage of Vrbo's free rewards program.
Are there any discounts for Santee vacation house rentals?
You can find great discounts on house rentals in Santee on Vrbo, including special rates on new listings and savings for weekly or monthly stays with top amenities such as a pool or parking. There are several discounts for Last minute bookings, and Early bird bookings too. The best part is, there's no need for a discount code—just enter your travel dates and apply the discount filters to view the top rates.
Where are the best areas for renting a beach house in Santee?
For renting a beach house in Santee, South Carolina, travelers should focus on the nearby Santee Cooper Lakes area, specifically around the shores of Lake Marion and Lake Moultrie. This region is known for its serene waterfront properties that offer easy access to fishing, boating, and other water activities. Many vacation rentals here come with private docks, outdoor grills, and expansive decks or patios, allowing guests to fully enjoy the beautiful lake views and the pleasant South Carolina weather.

The area surrounding Santee State Park is particularly appealing, where visitors can find cozy cabins and larger homes located among the trees, often featuring amenities such as fully equipped kitchens, fireplaces, and access to hiking trails. The park itself provides opportunities for outdoor recreation, including hiking, biking, and wildlife watching, making it a great destination for nature lovers.

Additionally, Santee is conveniently located near local shops and dining options, where travelers can experience Southern cuisine and fresh seafood.
What is the most popular type of vacation rental accomodation in Santee?
In Santee, condos are the most popular type of vacation rental, with about 91 available in the area. These condos are often located near the scenic Santee State Park and Lake Marion, providing easy access to outdoor activities such as fishing and hiking. Travelers can expect amenities like fully equipped kitchens, comfortable living spaces, and access to community facilities such as swimming pools and picnic areas.

In addition to condos, there are several vacation houses and cottages available, suiting families and larger groups. These homes typically feature multiple bedrooms, spacious yards, and outdoor seating areas, making them ideal for gatherings and relaxation after a day of exploring the beautiful surroundings.
Are there any family house rentals in Santee?
In Santee, South Carolina, there are numerous family-friendly house rentals available, with around 93 properties to choose from. This charming area is known for its beautiful lakes and outdoor activities, making it an ideal destination for families. Many homes offer spacious living areas, fully equipped kitchens for preparing family meals, and outdoor spaces great for gatherings or kids to play.

Visitors can enjoy close proximity to Santee State Park, where hiking and fishing opportunities abound, as well as the scenic Santee Cooper Lakes, which are great for boating and swimming. Additionally, some rentals may feature amenities like private docks, game rooms, or picnic areas, enhancing the overall experience for families looking to create lasting memories together.
Can I rent a vacation home with a pool or hot tub in Santee?
In Santee, there are numerous vacation homes available for rent that feature pools and hot tubs, with around 91 options to choose from. This charming town, known for its proximity to Lake Marion, offers a variety of rental properties that cater to different preferences. Many homes come equipped with private pools, outdoor seating areas, and hot tubs, making them ideal for relaxation after a day of activities.

Travelers can expect amenities such as fully equipped kitchens, spacious living areas, and outdoor grills, great for family gatherings or entertaining friends. Find your rental in Santee with a pool or a hot tub.
Can I find long-stay vacation rentals in Santee?
A long-stay vacation rental in Santee is the best way to experience local living. Plus, you can make the most of long-stay discounts. For month-long stays, save an average of 19%, and for week-long bookings you can save an average of 10%.* Long-stay discounts are applied automatically when you enter your vacation dates into the search tool, or you can use the "Weekly stay" and "Monthly stay" filters in your search.

*Based on analysis of Vrbo booking and occupancy data for 2024 stays.
Are there pet-friendly house rentals in Santee?
In Santee, there are several pet-friendly house rentals available, making it an excellent choice for travelers looking to bring their furry friends along. Many of these vacation homes offer spacious interiors, fully equipped kitchens, and outdoor areas where pets can enjoy the fresh air. Some properties may also include amenities such as fenced yards, patios, and barbecue grills, superb for family gatherings or relaxing evenings.

The Santee area is known for its proximity to Lake Marion, which provides ample opportunities for outdoor activities like fishing, boating, and hiking. The Santee State Park is a highlight, featuring trails and picnic spots where pets are welcome, ensuring that both visitors and their pets can explore the natural beauty of the region together.
Are there any remote work vacation rentals in Santee?
In Santee, South Carolina, travelers looking for remote work vacation rentals will find a substantial selection, with around 100 properties available. Many of these rentals come equipped with essential amenities for remote work, including reliable Wi-Fi, dedicated office spaces, and desks suitable for productivity. Guests can expect comfortable living environments that foster both relaxation and focus, often featuring spacious layouts and well-appointed kitchens for convenient meal preparation.

The area is known for its picturesque landscapes, including nearby Lake Marion, where outdoor activities like fishing and boating are easily accessible during downtime. Santee also offers a peaceful atmosphere, making it an ideal choice for those seeking a balance between work and leisure. To help narrow your search, insert your dates and apply the "WiFi" filter on Vrbo.
Are there any Santee vacation rentals with parking?
Vrbo offers a wide selection of vacation rentals in Santee with parking available—perfect for families or travelers who value the convenience of having a car during their stay. To easily find these properties, simply enter your travel details on Vrbo and use the "Parking available" filter under the amenities section. This makes it quick and easy to browse listings that suit your needs, whether you're planning a short city break or a longer stay.
What are popular rental amenities in Santee?
In Santee, popular vacation rental amenities include kitchens, allowing guests to prepare their own meals, and onsite parking for convenience. Many rentals also feature coffee and tea makers for those who enjoy a warm beverage in the morning. Outdoor spaces are commonly available, with decks or patios and balconies providing areas to relax and enjoy the pleasant surroundings.
When is the best time to visit Santee for a vacation rental?
The best time to visit Santee for a vacation rental is during the peak season, which spans from March to May, with April being particularly popular. This vibrant time of year draws travelers eager to enjoy the mild temperatures and abundant outdoor activities that Santee has to offer. With daytime highs typically reaching the mid-70s to low 80s Fahrenheit, conditions are ideal for fishing, boating, and golfing in the picturesque surroundings of Santee State Park and Lake Marion.

During April, visitors can experience the beauty of blooming flowers and lush greenery, making it great for scenic walks and picnics by the lake. The pleasant weather also invites plenty of opportunities for birdwatching and wildlife spotting, appealing to nature enthusiasts who appreciate the rich biodiversity of the region.

For those looking for a more budget-friendly option, November presents a wonderful alternative. This shoulder month allows for quieter exploration, with fewer crowds and a chance to enjoy the tranquil beauty of Santee's fall landscapes. It's a great time for reflective outdoor activities and enjoying the crisp, cool air.
How early should I book a Santee vacation rental?
Book your Santee vacation rental at least two months before you travel for the best selection of properties.* Plus, you'll typically find that the earlier you book your vacation rental, the better the price.

*Based on analysis of Vrbo booking and occupancy data for 2024 stays.
What are the top attractions in Santee, South Carolina, United States of America?
In Santee, South Carolina, visitors can enjoy a variety of attractions that highlight the area's natural beauty and outdoor recreational opportunities. Lake Marion is a central feature, offering activities like fishing, boating, and picnicking along its scenic shores. The Santee State Park is another highlight, where guests can explore hiking trails, campgrounds, and nature observation areas, superb for those looking to immerse themselves in the local wildlife.

For golf enthusiasts, the Santee Cooper Resort area features several top golf courses that provide beautiful views and challenging gameplay. Additionally, the Santee National Wildlife Refuge offers opportunities for birdwatching and hiking, showcasing the rich biodiversity of the region. The town itself also hosts local shops and eateries, making it easy for visitors to experience Southern hospitality and local cuisine.
Can I change or cancel my Santee home rental booking on Vrbo?
To find Santee vacation rentals with free cancellation, just use Vrbo's handy "Free cancellation" search filter. We get that plans can change, so it's easy to filter properties that give you flexibility. If you need to make changes to an existing booking, drop your host a message. Go to "My Trips" in your account, click "Change or Cancel" and then "Message Host". Vrbo rentals give you the privacy of having the entire place to yourself, and for extra flexibility, some travelers can choose to pay over time with Affirm. Whether you're adjusting your plans or looking for flexible payment options, Vrbo makes it easy to book with confidence.
Why should I join Vrbo as a host?
Joining Vrbo as a host opens the door to a global community of travelers seeking unique stays, giving you the opportunity to earn income from your property on your terms. With user-friendly tools, dedicated support, and exposure on major travel sites, Vrbo makes it easy to list, manage, and succeed. Whether it's a cozy cabin or a beach condo, you can turn your space into a standout destination, become a host and let Vrbo handle the heavy lifting to help you thrive.

Earn a Premier Host badge by providing quick, reliable communication and consistently delivering outstanding guest experiences.
Are all fees included in the Santee vacation rental prices shown on Vrbo?
Vrbo provides upfront pricing from the moment you start your search. There are no hidden fees added during the check-out process. This allows you to compare properties with ease and plan your trip with confidence.
What is VrboCare™ and how does it work?
Vrbo's mission is to help guests relax, reconnect, and enjoy precious time together. With VrboCare™, you can have peace of mind knowing you're protected and that if something goes wrong, we will do our best to make it right as applicable.

If a significant issue arises that your host can't resolve, we'll help you address it, find a similar property, or get your reservation refunded if applicable. That's our promise. If a home is significantly different than listed, we'll get you into a new space that meets your needs and makes it right, or if a host cancels before your stay, you have a dedicated support team to get you into a similar home as applicable.
What can I expect from Vrbo customer service and VrboCare™ support?
Your peace of mind is our priority. Whether you're planning your trip or have already finished your stay, VrboCare™ is here to support you every step of the way. For urgent situations like last-minute cancellations, booking issues, or potential fraud, Vrbo customer service is available 24/7 to help resolve problems quickly and effectively.

Vrbo also offers support via live chat through our Help Center, where you can find helpful resources on bookings, payments, property management, and safety, making it easy to get instant answers to many common questions.
Can I plan a group trip on Vrbo?
Vrbo's Trip Planner makes organizing group trips easy and stress-free. Whether you're planning with friends or coordinating a large group, you can collaborate in one place, save and share properties, vote on favorites, and build the perfect itinerary together.

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