Entire home

Serenity South -- Gardens, River-Views, and Refreshing Space

Overview
Amenities
Policies
Location
Host

Exceptional

3 bedrooms1+ bathroomSleeps 51600 sq ft

Popular amenities

Kitchen
Fireplace
Outdoor space
Parking available

Explore the area

Cape Girardeau, MO

Riverfront Bridge Park
‪6 min walk‬
Isle Casino Cape Girardeau
‪16 min walk‬
Southeast Missouri State University
‪2 min drive‬
Cape Girardeau, MO (CGI-Cape Girardeau Municipal)
‪11 min drive‬

Rooms & beds

3 bedrooms (sleeps 5)

Back bedroom

1 Double Bed

Master bedroom

1 King Bed

Middle bedroom

2 Single Beds

1 bathroom, 1 half bathroom

Main floor bathroom

Toilet

Upstairs Bathroom

Bathtub or shower · Toilet

Spaces

Deck or patio

Porch or lanai

Kitchen

Balcony

Separate dining area

Outdoor play area

Garden

About this property

Serenity South -- Gardens, River-Views, and Refreshing Space

Beautifully renovated duplex with large shared yard in Cape Girardeau Historic District. Cozy living room, large dining room, fully stocked kitchen, 3 second-story bedrooms with balcony at the end of the hall, and 1 1/2 bathes. Perfect for getting away for rejuvenation or exploring downtown. Within walking distance to local downtown restaurants, antique shops, and boutiques. Two blocks from the Mississippi River and many other attractions.

Our prices include all fees. No hidden fees.

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Find out more

Add dates for prices

Amenities

Kitchen

Air conditioning

Outdoor space

Parking available

Fireplace

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Kitchen
Washer
Dryer
Free WiFi

House Rules

Check in after 4:00 PM

Minimum age to rent: 18

Check out before 11:00 AM

Children

Children allowed: ages 0–17

Excellent fenced back yard.

Events

Events allowed: family gatherings, birthday parties, weddings

Parties or events must okayed before arrival.

Pets

No pets allowed

Smoking

Smoking is not permitted

Back yard is shared with the other side of the duplex. Please respect their use of the common space.

Important information

You need to know

This property is managed by a professional host. The provision of housing is linked to their trade, business or profession.

Extra-person charges may apply and vary depending on property policy

Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges

Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed

Parties and events (including family gatherings, birthday parties and weddings) are allowed on site. Maximum attendees: 50

Note from host: Parties or events must okayed before arrival.

Host has indicated that there is a carbon monoxide detector on the property

Host has indicated that there is a smoke detector on the property

Safety features at this property include a deadlock

If you cancel your booking, you'll be subject to the host's cancellation policy. In accordance with UK consumer law, property booking services are not subject to the right of withdrawal.

We should mention

A car is not required for transport to and from this property

About the area

Cape Girardeau

Located in Cape Girardeau, this holiday home is on a river. The area's natural beauty can be seen at Shawnee National Forest and Mississippi River. Travelling with kids? Consider Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center. Discover the area's water adventures with power boating and fishing nearby, or enjoy the great outdoors with hiking and horse riding.

View more Holiday homes in Cape Girardeau

Cape Girardeau, MO

What's nearby

Riverfront Park - 2 min walk - 0.2 km
Riverfront Bridge Park - 6 min walk - 0.6 km
Isle Casino Cape Girardeau - 16 min walk - 1.4 km
Southeast Missouri State University - 2 min drive - 1.8 km
Show Me Center - 3 min drive - 2.8 km

Getting around

Cape Girardeau, MO (CGI-Cape Girardeau Municipal) - 12 min drive

Restaurants

‪Katy O'Ferrell's Publick House - ‬9 min walk
‪Sand's Pancake House - ‬11 min walk
‪Minglewood Brewery - ‬7 min walk
‪Roni’s Mac Bar - ‬16 min walk
‪Hotshots Sports Bar & Grill - ‬5 min walk

Frequently asked questions

Is Serenity South -- Gardens, River-Views, and Refreshing Space pet-friendly?

No, pets are not allowed at this property.

What time is check-in at Serenity South -- Gardens, River-Views, and Refreshing Space?

Check-in begins at 4:00 PM.

What time is check-out at Serenity South -- Gardens, River-Views, and Refreshing Space?

Checkout is at 11:00 AM.

Where is Serenity South -- Gardens, River-Views, and Refreshing Space located?

This family-friendly Cape Girardeau holiday home is located on a river, steps away from eDen Spa & Salon, Shawnee National Forest and Mississippi River. Riverfront Park and Riverfront Bridge Park are also within 5 minutes.

Exceptional

Reviews are presented in chronological order, subject to a moderation process, and verified unless otherwise labelled.

Learn more

10/10

Cleanliness

10/10

Property conditions & facilities

10/10

Check-in

10/10

Communication

10/10

Location

10/10

Listing accuracy

10/10 Excellent

Tracy H.

1 Aug 2025

Liked: Cleanliness, check-in, communication, location, listing accuracy

Such a great place and location

Stayed 2 nights in Jul 2025

10/10 Excellent

Jodie F.

26 Jul 2025

Liked: Cleanliness, check-in, communication, location, listing accuracy

Enjoyed everything! Great location!

Stayed 4 nights in Jul 2025

10/10 Excellent

Vicki R.

9 Jun 2025

Liked: Cleanliness, check-in, communication, location, listing accuracy

Beautiful house. Great stay. Would definitely stay again!

Stayed 1 night in Jun 2025

10/10 Excellent

Donna D.

11 Aug 2025

Liked: Cleanliness, check-in, communication, location, listing accuracy

Lovely as always

Moving our daughter in to the dorm at SEMO for yr 2. Been coming to this location since our trip here during her senior year of HS when she visited SEMO to audition for the musical theatre program. It is a great place to stay when you have more than 2 people.

Stayed 1 night in Aug 2025

10/10 Excellent

Bryan P.

1 Jul 2025

Liked: Cleanliness, check-in, communication, location, listing accuracy

Comfortable & Clean

Great Location short walking distance to the Downtown Area with lots do do, Restaurants, Water Park, Shopping. This is the 2nd time I have stayed and it is a true delight. Very spacious and comfortable. Easy to communicate with the Owner/Manager. I will be staying there again in the future. I recommend it with 5 Stars!

Stayed 1 night in Jun 2025

10/10 Excellent

Linden S.

1 Jun 2025

Liked: Cleanliness, check-in, communication, location, listing accuracy

A Beautiful Retreat for Three Generations

Three generations found rest,beauty,& joy at Serenity South. Thoughtful touches,beautiful gardens and Cape charm made this more than a stay-it became a treasured memory. We were so appreciative of the details, the fresh flowers, homemade cookies, the coffeemaker upstairs and the books and games. The beds were all comfortable. We enjoyed this historical home and our stay.

Stayed 2 nights in May 2025

10/10 Excellent

Nichole C.

25 Jul 2025

Liked: Cleanliness, check-in, communication, location, listing accuracy

Serenity south was welcoming comfortable and very clean. Impeccably maintained historic home. Comfortable beds, great water pressure and shower head, easy to maintain consistent temperature. Good vibes throughout. Not haunted. Beautiful outdoor space but it was too hot to use it much while we were there. Recommend stopping by the olive oil store William and Water across the street.

Stayed 3 nights in Jul 2025

10/10 Excellent

Penny F.

28 Mar 2025

Liked: Cleanliness, check-in, communication, location, listing accuracy

Beautiful getaway!

The property was exactly as listed with so many little touches that made it special. Communication was great and we were close to downtown shops and the casino. We will definitely stay again when we are in the area.

Stayed 2 nights in Mar 2025

10/10 Excellent

Sam E.

19 Apr 2025

Liked: Cleanliness, check-in, communication, location, listing accuracy

Downtown home with great character

My son and two brothers stayed a night in this lovely home. I travel to Cape frequently to visit my son and will definitely stay here again.

Stayed 1 night in Apr 2025

10/10 Excellent

STEPHANIE L.

19 May 2025

Liked: Cleanliness, check-in, communication, location, listing accuracy

In town for one day

Its was different, but over all it was on point.I will rebook this summer

Stayed 1 night in May 2025

10/10 Excellent

Michelle K.

28 Mar 2025

Liked: Cleanliness, check-in, communication, location, listing accuracy

Perfect home for college visit

When looking for a VRBO for our daughter's college visit, we knew the perfect place to stay! This is our second stay at Serenity South and it was just as incredible as the first visit. Clean, inviting and cozy. Thanks Jo for another beautiful stay.

Stayed 1 night in Feb 2025

10/10 Excellent

John

10 Dec 2023

Liked: Cleanliness, property conditions & facilities, communication

Great place.

Stayed 1 night in Dec 2023

10/10 Excellent

Rhonda S.

23 Feb 2025

Liked: Cleanliness, check-in, communication, location, listing accuracy

Smith Women’s Weekend

We had a wonderful time at Serenity South! The house is quiet and very clean, in walking distance of fantastic shops and fun places to eat. We look forward to returning next year!

Stayed 2 nights in Feb 2025

10/10 Excellent

Tim B.

28 Oct 2022

Liked: Cleanliness, check-in, communication, location, listing accuracy

Great stay

Beautiful home, great location, well equipped kitchen.

Stayed 5 nights in Oct 2022

10/10 Excellent

Bradley T.

1 Jul 2024

Liked: Cleanliness, check-in, communication, location, listing accuracy

Peaceful place

Very nice and beautiful place super nice people

Stayed 2 nights in Jun 2024

10/10 Excellent

Terry M.

22 Apr 2024

Liked: Cleanliness, check-in, communication, location, listing accuracy

Great family getaway

Everything was perfect. From check in to check out. Great neighborhood and location.

Stayed 1 night in Apr 2024

10/10 Excellent

Candice L.

11 May 2024

Liked: Cleanliness, check-in, communication, location, listing accuracy

Family Graduation

The place was perfect for our stay and was close to the farmers market and downtown shops. Highly recommend for location!

Stayed 1 night in May 2024

10/10 Excellent

Steve B.

4 Nov 2024

Liked: Cleanliness, check-in, communication, location, listing accuracy

Excellent choice

Very nice property. Highly recommend.

Stayed 2 nights in Oct 2024

10/10 Excellent

Danita D.

18 Sept 2023

Liked: Cleanliness, check-in, communication, location, listing accuracy

Historic charm

We loved staying at this house for SEMO family weekend! It was super clean and had everything we needed and more 😊 we will definitely try to stay here again!

Stayed 1 night in Sep 2023

10/10 Excellent

Tim B.

15 Oct 2023

Liked: Cleanliness, check-in, communication, location, listing accuracy

Homecoming

As always, a fantastic place to stay.

Stayed 2 nights in Oct 2023

10/10 Excellent

Cheryl R.

14 Aug 2023

Liked: Cleanliness, check-in, communication, location, listing accuracy

Repeat guest

Great home away from home for our visits to Cape.

Stayed 3 nights in Aug 2023

10/10 Excellent

Nolan R., Tacoma, WA

28 Oct 2019

Liked: Cleanliness, check-in, communication, location, listing accuracy

Wonderful all around!

Great location and property! Stayed with several friends and it’s offered lots of space for everyone. Very close to many downtown attractions! Would definitely stay again!

Stayed 2 nights in Oct 2019

10/10 Excellent

Tracy H.

2 Sept 2024

Liked: Cleanliness, check-in, communication, location, listing accuracy

Great location and responsive

We were a last minute stay and Jo quickly accommodated. She had the air conditioning on for us and fresh flowers. So wonderful

Stayed 3 nights in Aug 2024

10/10 Excellent

Nicholas H.

31 Mar 2021

Liked: Cleanliness, check-in, communication, location, listing accuracy

Cool vintage place in a great town

Loved it!

Stayed 1 night in Mar 2021

10/10 Excellent

Wendy M.

6 Nov 2023

Liked: Cleanliness, check-in, communication, location, listing accuracy

Excellent location

This was a very cute home - well maintained! Perfect location. Had everything we needed. Very clean!!

Stayed 1 night in Oct 2023

About the host

Hosted by Jo Pincosy

Languages:

English

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Serenity South -- Gardens, River-Views, and Refreshing Space

Photo gallery for Serenity South -- Gardens, River-Views, and Refreshing Space

Reviews

Popular amenities

Explore the area

Rooms & beds

3 bedrooms (sleeps 5)

Back bedroom

Master bedroom

Middle bedroom

1 bathroom, 1 half bathroom

Main floor bathroom

Upstairs Bathroom

Spaces

About this property

Serenity South -- Gardens, River-Views, and Refreshing Space

Protect your payment — always book on Vrbo

Add dates for prices

Amenities

Have a question?

Similar properties

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EN11: Downtown Penthouse with roof deck! AMAZING VIEW! - 5 mins away downtown

House Rules

Children

Events

Pets

Smoking

Important information

You need to know

We should mention

About the area

Cape Girardeau

What's nearby

Getting around

Restaurants

Frequently asked questions

Reviews

Exceptional

10/10

10/10

10/10

10/10

10/10

10/10

Reviews

10/10 Excellent

Tracy H.

Tracy H.

10/10 Excellent

Jodie F.

Jodie F.

10/10 Excellent

Vicki R.

Vicki R.

10/10 Excellent

Donna D.

Lovely as always

Donna D.

10/10 Excellent

Bryan P.

Comfortable & Clean

Bryan P.

10/10 Excellent

Linden S.

A Beautiful Retreat for Three Generations

Linden S.

10/10 Excellent

Nichole C.

Nichole C.

10/10 Excellent

Penny F.

Beautiful getaway!

Penny F.

10/10 Excellent

Sam E.

Downtown home with great character

Sam E.

10/10 Excellent

STEPHANIE L.