✨ Deaconess Guesthouse — Iconic Luxury on the Ohio River · Steps from Louisville & Historic Jeffersonville ✨
Where History, Luxury & Riverfront Living Come Together
Welcome to Deaconess Guesthouse, an 1800s architectural treasure reimagined into a premier luxury retreat. Once Jeffersonville’s first public hospital, this landmark estate has been exquisitely restored by Charming Vacation Homes to blend timeless character with boutique-hotel sophistication, all framed by panoramic Ohio River views.
Perfectly situated minutes from Downtown Louisville, the Bourbon Trail and Jeffersonville’s vibrant riverfront district, this one-of-a-kind residence offers guests a stay that feels meaningful, elevated and entirely unforgettable.
⭐ Crafted for Elevated Gatherings & Exceptional Stays
Featuring 8 designer bedrooms and 6 spa-inspired bathrooms across four private suites, Deaconess Guesthouse accommodates up to 24 guests—ideal for:
- Corporate & executive retreats
- Multi-family getaways
- Wedding groups & milestone celebrations
- Holiday gatherings & special events
Every room has been thoughtfully curated with rich textures, custom artwork, premium furnishings, and inviting spaces perfect for conversation, connection, and lasting memories.
⭐ Signature Luxury Experiences
1. Private Hot Tub & Fire Pit: Unwind under the stars with serene riverfront views.
2. Wraparound Porches & Balconies: Enjoy morning coffee or sunset cocktails overlooking the water.
3. Stargazing Dome: A unique, whimsical retreat for dreamers, creatives, children & romantics.
4. Ample On-Site Parking: Perfect for corporate groups, event planners, and large gatherings.
⭐ Unmatched Location for Exploration
- Walk to Downtown Jeffersonville: Charming boutiques, local eateries, festivals & waterfront entertainment.
- 2.5 Miles to Downtown Louisville: Distilleries, Churchill Downs, museums, concerts, sports & nightlife.
- Outdoor Adventures: Paddleboarding, biking, and seasonal riverfront events right outside your door.
⭐ Your Private Luxury Riverfront Estate
Whether you're sharing stories by the fire pit, hosting an intimate celebration or relaxing on a rocking chair as riverboats drift by, Deaconess Guesthouse offers a setting designed to help you slow down, savor the moment and reconnect.
With its historic soul, elevated finishes and unrivaled riverfront setting, Deaconess Guesthouse isn’t just a place to stay—it’s an experience, a gathering place and a memory that becomes part of your story.
⭐ Now Booking Exclusive Stays & Private Events
Perfect for:
1. Executive & team retreats
2. Multi-family vacations
3. Weddings, anniversaries & milestone celebrations
4. Holiday gatherings & friends’ escapes
Reserve your stay today at Louisville & Jeffersonville’s premier luxury estate—where history, elegance and unforgettable moments come together.
★ CONVENIENT LOCATION
The house is centrally located and is within a 10-15 minute Uber/Lyft drive to most locations:
- Big Four Walking Bridge (Connecting KY and IN) - 0.4 miles (2 mins)
- KFC Yum Center - 2.3 miles (7 mins)
- Churchill Downs (DERBY) - 7.7 miles (15 mins)
- Downtown Louisville/ 4th Street Live - 2.4 miles (6 mins)
- Waterfront Park - 3.4 miles (9 mins)
- Papa Johns Stadium (Cardinal Stadium) - 6.4 miles (11 mins)
- Kentucky Fairgrounds - 6.5 miles (10 min)
- University of Louisville - 6.5 miles (12 mins)
- Kentucky Exposition Center - 6.7 miles (11 mins)
- Kentucky Kingdom - 7.4 miles (13 mins)
- Highland Festival Grounds - 8.5 miles (12 mins)
- Louisville Airport - 8.6 miles (10 mins)
- Louisville Mega Cavern - 10.2 miles (19 mins)
- UPS Worldport - 11.2 miles (20 mins)
- Ford LAP Plant - 10.9 miles (16 mins)
- Waverly Hills Sanatorium - 17 miles (30 mins)
- Valhalla Golf Club - 19 miles (27 mins)
PROPERTY HIGHLIGHTS
🌅 Exceptional Riverfront Living: Wake up to sweeping panoramic views of the Ohio River—where every sunrise feels magical. Stroll to the vibrant downtowns of Jeffersonville and Louisville for boutique shopping, award-winning dining, live entertainment and year-round festivals just moments from your door.
🏛️ Historic Beauty Meets Modern Luxury: This iconic landmark has been meticulously restored and elegantly reimagined. Timeless craftsmanship blends seamlessly with modern sophistication—designer décor, curated furnishings and preserved architectural details create a space that’s both luxurious and irresistibly inviting.
🌿 Serene Outdoor Retreats: Sip morning coffee or unwind with evening cocktails on covered porches and private balconies overlooking the shimmering river. Every outdoor space is thoughtfully designed to capture the tranquility and magic of waterfront living.
🤝 Crafted for Connection: With 8 beautifully appointed bedrooms and 6 spa-inspired bathrooms, the home offers extraordinary comfort for families, friends and group getaways. Sunlit living areas and cozy gathering spaces inspire conversation, laughter, and unforgettable moments.
🍳 Elevated Culinary Experiences: Four fully equipped gourmet kitchens feature premium appliances and chef-forward layouts—perfect for celebrations, home-cooked meals or hiring a private chef for a memorable dining experience.
🐾 Thoughtful for Families & Pets: Cozy reading corners, kid-friendly nooks and pet-welcoming touches ensure every guest—big, small or four-legged—feels right at home.
🔥 Your Private Outdoor Oasis: Relax in the hot tub, gather around the riverfront fire pit, unwind under the gazebo or Hyperdome, dine alfresco or play lawn games under the stars. Every corner of the outdoor sanctuary is designed to refresh and reconnect.
🕹️ Endless Entertainment: Smart Roku TVs, indoor and outdoor games and multiple lounge areas offer endless ways to play, unwind and enjoy your stay.
🎉 Perfect for Groups, Retreats & Celebrations: Ideal for family reunions, corporate retreats, milestone events or extended getaways. Enjoy generous parking, four washer/dryer sets and flexible indoor/outdoor spaces perfect for hosting memorable gatherings.
🏞️ A Signature Riverfront Experience
Discover the perfect fusion of historic charm, elevated comfort and unbeatable location—where the beauty of the Ohio River sets the tone for an unforgettable stay and every visit becomes part of your story.
NOTE:
1) Must be 25 or older to book.
2) Please review house rules before booking. Rental Agreement & Security Hold: Guests must e-sign our rental agreement and Must submit a $500 off-platform security hold that will be collected upon signing rental agreement but it will not be placed until 2 days prior to arrival and released 7 days after departure, if no damages are reported. Please note we are API Connected to a hotel-style software called OwnerRez to safely and securely take off-platform security deposits.
3) *** STRICT CANCELLATION for DERBY/ Bourbon & Beyond ***
4) Visitors are not permitted unless you make a special request to the host and receive approval.
5) We have exterior surveillance with voice and recording capabilities of the parking area and front door. They are in place for security of guests and the home. We do NOT have interior cameras nor camera in the backyard.
6) The Dome is not recommended for use during hot summer months. We suggest enjoying the other amenities during warmer months for optimal comfort.
7) We cannot accommodate early check-ins or late check-outs for same-day turnarounds.
8) For days without same-day turnarounds, we offer early check-ins and late check-outs at the following rates: $100 for up to 2 hours, $250 for 2 to 4 hours, and a full day's rate for more than 4 hours.
9) Please note that for cancellations of bookings made on platforms other than Airbnb, a Stripe card processing fee of 3% will be deducted from the total refund.
❗PLEASE REVIEW THE HOUSE RULES BEFORE BOOKING. THANK YOU ❗