State Historical Society of Iowa Museum featuring a high-rise building, landscape views and a city

Downtown Des Moines holiday rentals

We found 208 holiday rentals — enter your dates for availability

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Dates

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Flexible dates

September 2025

October 2025

Discover a selection of 11 homes, 132 apartments and other holiday rentals in Downtown Des Moines that are perfect for your trip. Whether you're going on holiday with family or friends, holiday rentals have the amenities that you expect for your stay, including air conditioning and cable TV. You'll be able to choose a property to rent for everyone's needs, including places that are non-smoking or accessible.

Holiday rentals with weekly discounts - Downtown Des Moines

Showing deals for:28 Nov - 5 Dec

Exceptional

(6 reviews)

Stunning Penthouse - King Bed - City/River View - Corner Unit - Wells Fargo

Des Moines, IA

20% off

S$407 per night

includes taxes & fees

Secluded outdoor fire pit space. Patio with grill and 6 person hot tub.

Exceptional

(60 reviews)

The Cow Tipper: Near Everything - SPA - Game Room - Fire Pit & Patio - Sleeps 10

Des Moines, IA

12% off

S$336 per night

includes taxes & fees

Exceptional

(8 reviews)

Free Parking and Gym - Loft Near Wells Fargo Arena Downtown - Stocked Kitchen

Des Moines, IA

21% off

S$262 per night

includes taxes & fees

Exceptional

(7 reviews)

Industrial BOHO Apartment -Free Parking- 5 mins from Drake University-Downtown

Des Moines, IA

8% off

S$248 per night

includes taxes & fees

Wonderful

(7 reviews)

Cozy 1-bedroom in the heart of Des Moines, walking distance to many places!

Des Moines, IA

8% off

S$172 per night

includes taxes & fees

Front view of property with rooftop garden above

Exceptional

(105 reviews)

Loft in Quaint East Village boasting a skyline view of Downtown

Des Moines, IA

8% off

S$409 per night

includes taxes & fees

Find spaces that suit your style

House

Condo/Apartment

Find properties near top attractions in Downtown Des Moines

Principal Park

Find the best place to stay - Downtown Des Moines

Kasa Downtown Des Moines

Sleeps 4 · 1 bedroom

• Casa Dean sleeps 20 close to Fairgrounds and Downtown Des Moines •

Sleeps 20 · 5 bedrooms · 3 bathrooms

Peace of mind
Our Book with Confidence guarantee gives you 24/7 support
More quality time
From booking to staying, the whole process is simple and enjoyable
All the privacy of home
Enjoy full kitchens, laundry, pools, gardens and more
More for less
More space, more privacy, more amenities — more value

Frequently asked questions

What is the most popular type of holiday rental accommodation in Downtown Des Moines?

Apartments are the most popular kind of holiday rental in Downtown Des Moines, according to our data. Even if you have a different vision in mind, Vrbo has holiday homes in all shapes and sizes. Browse our options to find your perfect pad.

How much does it cost to rent a holiday rental in Downtown Des Moines?

A number of things can affect what you'll pay for your holiday rental in Downtown Des Moines, including the season, length of stay and type of property. But, all our holiday homes have something in common — exceptional value. Just add your travel dates to find your home away from home.

How much does it cost to rent a beach house in Downtown Des Moines?

The average price for a holiday home near the beach in Downtown Des Moines depends on when you're going and the style and size of property you want. Find prices easily and quickly on Vrbo by entering your preferred travel dates. Then use the handy filter tool to choose the number of bedrooms and amenities that you prefer, like air conditioning, WiFi and a hot tub.

Are there pet-friendly holiday rentals in Downtown Des Moines?

Yes. Take your pick of 84 holiday homes that welcome pets in Downtown Des Moines on Vrbo. Our furry best friends also deserve a little time out, so simply use our search function for pet-friendly holiday rentals to book a perfect pad where Rover can lap up the fun.

Can I rent a house with a pool in Downtown Des Moines?

Tick the "pool" box in our handy filter tool and select from nine houses with private pools in Downtown Des Moines on Vrbo. Ball games, gentle soak or noodle joust? Leisure activities are up to you when your Vrbo holiday home comes with its own swimming pool.

What are popular rental amenities in Downtown Des Moines?

When it comes to rental amenities that guests are looking for in Downtown Des Moines, a swimming pool, a barbecue grill and nearby museums rank highest. With Vrbo holiday homes, there are choices to fit your taste and style, whether you're going on a trip with friends, family or even pets.

Are there large group holiday rentals in Downtown Des Moines?

With 25 Downtown Des Moines properties that can accommodate a group of five or more people, you can invite a few extra family members or buddies along. Whether you're planning a casual get-together or a special celebration, we'll help you find a comfortable space to fit the occasion.

Are there holiday rentals in Downtown Des Moines that welcome kids?

Gather your whole crew for fun-filled adventures in Downtown Des Moines at one of our 84 family-friendly holiday properties. A lot of these stays provide amenities that are great for trips with the little ones, including dining rooms, extra bedrooms and outdoor spaces. Just check the "Properties good for families" filter and choose your favourite option.

What are the top attractions for families in Downtown Des Moines?

Keeping the kids entertained during your holiday in Downtown Des Moines is a breeze with these fabulous family-friendly attractions:

Blank Park Zoo
Science Centre of Iowa
State Historical Society of Iowa Museum

Are there one-bedroom holiday rentals in Downtown Des Moines?

Yes, you can choose from 48 one-bedroom rentals in Downtown Des Moines. Whether you want a cosy cottage or an upmarket condo, our one-bedroom rentals are just right if you don't require tons of space. One of the best parts about having your own place? You won't have to share your getaway with strangers.

Can I find two-bedroom holiday rentals in Downtown Des Moines?

Gather your loved ones and enjoy total privacy and comfort in one of the 22 two-bedroom holiday homes Downtown Des Moines has to offer.

Are there holiday rentals with WiFi in Downtown Des Moines?

There are 26 holiday rentals with WiFi in Downtown Des Moines. If you want to disconnect from the world during your escape, but still want to be connected to the web, these properties are just what you need. Narrow your search by applying the WiFi filter on Vrbo.

How can I find holiday rentals with air conditioning in Downtown Des Moines?

You can pick from 84 Vrbo holiday homes with air conditioning in Downtown Des Moines providing that gentle, cool breeze and extra level of comfort. Simply enter your preferred travel dates and then use our handy filter tool to help you find stays with air conditioning.

How old do you have to be to rent a holiday rental in Downtown Des Moines?

The minimum age can differ between properties on Vrbo, so look at the rules of the holiday home in Downtown Des Moines you want to book. But normally, it's 16, 18 or 21.

How long can I rent a holiday rental in Downtown Des Moines for?

The amount of time you can stay in a Downtown Des Moines holiday home for is up to each property. Simply enter your preferred travel dates to view available options that offer long-term stays. They have all the things you need to make your extended trip more enjoyable and convenient, like kitchens and air conditioning. Some properties may also offer weekly or monthly discounted prices, so you can hang around longer for less.