I was brought up in this neighborhood. It is a residential area that is very safe with everything that you might need within walking distance(supermarkets, bakeries, coffee shops, fruit markets, traditional Greek restaurants, pharmacies, commercial shops, banks, etc).
While it is central, it is very quiet and safe. The main advantage is that you will need about 15 minutes to get anywhere in the historical centre while you are just 500 metres away from National Road.
Through metro network (Ag. Eleftherios) you can go easily from the one side of the city to the other in order to see every corner and aspect of Athens. Acharnon and Patission streets are 300 metres from home. From there, buses leave on a very frequent base for Monastiraki, Thissio and Constitution Square as well as to North (Kifissia) and South (Piraeus). The daily travel card for all means of transportation costs 4,5€ and the five-day card costs 9€ which we can supply on your behalf upon request.
If you have a car then the National Highway is 500 meters away with easy access to both directions (North and South) while Acharnon and Patission streets (300 meters range) will take you downtown in 10 minutes.