Discover a selection of 1,000 vacation rentals in Panama that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including swimming pools and WiFi. Prices start at $61 per night, and houses and condos are popular options for a stay in Panama. Either way, you'll find a rental for everyone's needs.
Top rated rentals — Panama
Things to do

Picturesque plazas in Panama City

Choosing a Panama vacation rental in the capital is the best bet if you want to tick the star attractions off your to-do list. Cutting through the country and linking the Atlantic and Pacific Oceans, the 77-kilometer Panama Canal is the most famous of them. A major shipping route first used in 1914, the waterway's rich history can be discovered at the Interoceanic Canal Museum. Small but perfectly formed, Casco Viejo is Panama City's coolest, smallest and oldest neighborhood. Rebuilt in the late-1600s after being destroyed by pirates, the UNESCO World Heritage Site is home to crumbling churches, beautifully-restored colonial facades and picturesque plazas.


Feel the heat in sun-soaked Panama

Wherever you choose your Panama vacation rental, the climate doesn't vary too much, unless you're up in the mountain ranges, where it's much cooler. Boasting a tropical climate, Panama maintains a high and humid temperature all-year round, with an average high of around 86 degrees, good news if you enjoy hot weather. While visitors come here throughout the year, the dry season is the most-desirable time. It runs from mid-December through mid-April, with sporadic rain falling outside the season.

Natural features

Rivers, mountains and more in spectacular Panama

Hemmed between Colombia, Costa Rica and the Caribbean and Pacific Oceans, it's no surprise that Panama has such a diverse and spectacular landscape. Geographic features range from mysterious mangroves and rippling rivers that meander through valleys, to beautiful beaches and wild, impenetrable jungle. The dominant natural landmark is the verdant Cordillera de Talamanca mountain range, which sits beside the Costa Rica border. For wildlife lovers, Panama is a paradise. Visit the jungle to see creatures such as sloths, marmosets and capuchin monkeys, to name but a few.

What are the top-rated vacation rentals for weekend getaways in Panama?

Short on time but eager to get away? A weekend break is what you need. Reserve a couple of nights at one of these fantastic properties and get ready to feel worlds away from your Monday to Friday:

  • "Stunning Lakefront Beach House In Buenaventura" - Situated in El Chiru, there's plenty of fantastic stuff to see and do right on the doorstep of this rental property. Useful amenities like off-street parking options and cable/satellite TV services are the cherry on top!
  • "House" - This is another great place where you can unwind for a long weekend. Take advantage of a washing machine, a barbecue grill and more during your short but memorable stay at this El Chiru property.

Can I find studio apartments for rent in Panama?

Studio apartments are often on the smaller side, but it's tough to beat their great locations and modest price tags. Whether you're traveling by yourself or it's just the two of you, consider one of these sought-after studio apartments in Panama:

  • Settle in and get comfortable at "Studio", located in Rio Hato. There are plenty of amenities available here, including internet services and an elevator.
  • Start your day with a hot coffee and a cooked breakfast at "Beautiful Studio - Paradise In Panama". This Coloncito studio has all the conveniences you need to make your stay cozy, including free toiletries and a microwave oven.

Can I find short term rentals in Panama?

Spend a few days in a budget-friendly cabin or live life large in a luxury condo. Vrbo has lots of short-term rentals for your getaway to Panama. Take a look at these options for some inspiration:

  • Stay near the center of El Chiru and spend your days exploring the sights from "Stunning Lakefront Beach House In Buenaventura". Along with its handy location, this retreat has everything you need to make your vacation comfortable.
  • "House" also rolls out the welcome mat for short-term guests. Spend a couple of relaxing days at this property in El Chiru and find out why it's a favorite among many visitors.

What are the best romantic weekend getaways in Panama?

A romantic weekend getaway in Panama is a surefire way to stir up passions. Light a fancy candle, take your love by the hand and send sparks flying at one of these escapes:

  • Catch up on quality time and sweet snuggles at "Annsrental Luxury Beachfront - Stunning Views" in Boca Chica. A balcony and a restaurant dining guide are some of the little touches you'll find here.
  • Another alluring option is "Spectacularly Furnished Beach House" in Cocle. Enjoy amenities here including beauty services and a swimming pool, as well as each other's company.

Are there large vacation rentals that sleep 30 or more in Panama?

Whether you're planning a trip away with family and friends, a big birthday bonanza or even a wedding, we'll help you find the perfect home. Round up your best buddies and take a look at these large vacation rentals in Panama:

  • "Panama From The Sky In The Financial District": With 2 bedrooms accommodating up to 45 people, this vacation property in Campo Alegre has all the room you need. A swimming pool and off-street parking options are a couple of the amenities on offer here.
  • "Lovely Modern Apartment Two Bedrooms": Good times are guaranteed at this sought-after option in San Francisco. It has 2 bedrooms and can house up to 89 guests comfortably. Amenities here include a kitchen and a swimming pool.

What are the best houses for rent with a pool in Panama?

There's a good selection of houses with a pool in Panama, so pack your swim gear and get set to spend your days splashing about. Here are two top options to tempt you:

  • The pool at "Spectacularly Furnished Beach House" will add another dimension of fun to your break. Located in Cocle, this retreat also features outdoor furniture and a TV.
  • "Stunning Lakefront Beach House In Buenaventura" in El Chiru is also a hit with guests. There's plenty to like about this place besides its pool, such as a swimming pool and on-site watersports.

What are the best large family vacation rentals in Panama?

You can go all out on your guest list, because Vrbo has lots of family vacation rentals in Panama that'll lay out the welcome mat for your crew. Here are a few of our top picks:

  • Located in Cocle, "Spectacularly Furnished Beach House" has 4 bedrooms and can sleep up to 10 guests. Some of the handy amenities here include a nearby laundromat and a swimming pool.
  • Another top option, "House" in El Chiru comes with 4 bedrooms and accommodates up to 12 people. Cable/satellite TV services and a dishwasher will help keep your group feeling right at home.

Can I find family cabin rentals in Panama?

If you're organizing a trip with the family, choose one of these cabin rentals in Panama and give the kids an experience they'll always remember:

  • "Beachfront Property With Pool Is Your Own Piece Of Paradise" - Book a few nights or more at this getaway in Punta Barco. Amenities like cable/satellite TV services and daily housekeeping services will help make your stay comfortable.
  • "Cabin - Cabanas Potosi, El Valle De Anton" - Craft magic memories with the kids at this popular option. Located in El Valle de Anton, it features a separate dining area, a kitchen and more.

For more options, use the search bar at the top of the page and adjust the filters to find the Panama vacation rental that's perfect for your needs.