Where to stay around Southern Illinois, US?

Our 2019 property listings offer a large selection of 691 vacation rentals near Southern Illinois. From 256 Houses to 272 Condos/Apartments, find a unique house rental for you to enjoy a memorable stay with your family and friends. The best places to stay near Southern Illinois for a holiday or a weekend are on Vrbo.

What are the most popular destinations to visit in Southern Illinois?

There are many lovely places to stay for a holiday trip or just for a weekend in Southern Illinois. From Vrbo travelers, the top most popular destinations to visit are:

  • Kentucky: 1,911 vacation rentals
  • Saint Louis: 504 vacation rentals
  • Indiana: 1,796 vacation rentals
  • Missouri: 5,399 vacation rentals
  • Kentucky Lake: 299 vacation rentals

And Vrbo offers you the chance to discover many other popular destinations in Southern Illinois! Please use our search bar to access the selection of vacation rentals available in other popular destinations.

What are the main cities to discover in Southern Illinois?

Whether you're traveling with family or friends, here are the cities with the largest selection of vacation rentals for a holiday trip or just for a weekend in Southern Illinois:

  • Saint Louis: 504 rentals
  • Cadiz: 112 rentals
  • Carbondale: 111 rentals
  • Springfield: 19 rentals
  • Paducah: 38 rentals

For other cities, please use our search bar to access the selection of vacation rentals available.

Can I find easy-access vacation rentals when traveling by plane to Southern Illinois?

Yes of course. Our owners offer a large selection of vacation rentals near airports. The airports with a large selection of vacation rentals in Southern Illinois are:

  • Carbondale, IL (MDH-Southern Illinois): 64 vacation rentals
  • Lambert-Saint Louis International Airport (STL): 488 vacation rentals
  • St. Louis Downtown Airport (CPS): 451 vacation rentals

For other airports, please use our search bar to access the selection of vacation rentals available.

Near which points of interest can I spend my holidays in Southern Illinois?

Vrbo offers a large selection of rentals near lovely places in Southern Illinois. From Vrbo travelers, the top most popular points of interest to stay for a holiday trip or just for a weekend are:

  • Rend Lake: 17 rentals
  • Lake Barkley State Resort Park: 198 rentals
  • Busch Stadium: 460 rentals
  • Pennyrile Forest State Resort Park: 29 rentals
  • St. Louis Zoo: 476 rentals

But there are many other points of interest around Southern Illinois listed on Vrbo where you can find your place to stay. Just write your wanted destination in our search bar and have a look at our selection.

Explore destinations around Southern Illinois

Saint Louis
504 vacation rentals
Cadiz
112 vacation rentals
Carbondale
111 vacation rentals
Springfield
19 vacation rentals
Paducah
38 vacation rentals
Benton
129 vacation rentals
Murray
113 vacation rentals
St Charles
628 vacation rentals
Grafton
21 vacation rentals
Grand Rivers
76 vacation rentals
Gilbertsville
96 vacation rentals
Chesterfield
533 vacation rentals
Ste. Genevieve
16 vacation rentals
Marion
104 vacation rentals
Eddyville
102 vacation rentals
Goreville
59 vacation rentals
Kuttawa
172 vacation rentals
Clayton
411 vacation rentals
Makanda
106 vacation rentals
Carlyle
20 vacation rentals