Discover a selection of 2,500 vacation rentals in Mississippi, US that are perfect for your trip. Whether you’re traveling with friends, family, or even pets, Vrbo vacation homes have the best amenities for hanging out with the people that matter most, including swimming pools and private pools. Prices start at $130 per night, and cabins and houses are popular options for a stay in Mississippi. Either way, you'll find a rental for everyone's needs.
Top rated rentals — Mississippi
Destination guide

Mississippi is the birthplace of blues

Mississippi has some serious musical pedigree. Other than the one and only Elvis Presley, there's an endless list of notable musicians that have come out of this southern state. Without its musical heritage, we would have never heard the sounds of B.B. King or Howlin Wolf. Fast-forward to today and Mississippi isn't just known for its music, or its iconic river. Travelers come to stay in Mississippi vacation rentals to gorge on southern cuisine, walk in the national parks, or kick back on the sunny beaches that flank the Gulf of Mexico.

Things to do

Legends of Mississippi

If you're a fan of the King, then be sure to do the pilgrimage to the Elvis Presley Birthplace & Museum. It was 1935 when the little wooden house in Tupelo saw the birth of one of history's most iconic singers. Continue down your musical road with a visit to the B.B. King Museum, a place dedicated to the greatest blues musician the world ever knew. If you stay in a Mississippi vacation rental near Leland with kids, you're not going to want to miss the Jim Henson Exhibition, a museum which celebrates the life of the man who brought you the Muppets.


The Magnolia State of Mississippi awaits

The Magnolia State teems with outdoor space, whether it's mixed pine hardwood forests or the flat waterways of the delta. Other than winter sports, there are few outdoor activities that can't be done in the state. When you stay at a Mississippi vacation rental, you can glide down the waterways on kayaks, hike along the forested trails in the national parks, or set sail and spend a sunny afternoon on the Gulf of Mexico. If you're an angler, you've got plenty of peaceful banks to position yourself on, whether it's to cast into the sea or the mighty Mississippi River.


Skip the crowds in Mississippi

Apart from hurricane season, between September and October, there's no right or wrong time to book a Mississippi vacation rental. Summer sees the biggest influx of travelers, particularly along the coastal beaches. It's the hottest and most humid time to visit, but a cool breeze off the Gulf of Mexico keeps the climate feeling comfortable. If you'd prefer to skip the crowds and don't mind the drop in temperature, try the winter and spring, between November and April, when the vacation rental prices take a nosedive and the beaches and national parks are almost empty.

Natural features

Sea cows and black bears in Mississippi

The hills and valleys, deltas and pine woodland all make the perfect habitat for a range of wild creatures. If spotting wildlife is important, try to book a Mississippi vacation rental during late spring and summer, when the critters are out in force. Manatees, often called sea cows, are more associated with Florida. Throughout the summer, these gentle beasts work their way up the deltas and waterways of Mississippi. Further inland you might catch a glimpse of 1 of the 2 species of bear and keep your eyes peeled for gators that lurk around in the rivers.

How many vacation rentals are available around Mississippi, US?

Our 2022 property listings offer a large selection of 2,493 vacation rentals around Mississippi. From 250 cabin rentals to 1,627 house rentals, find a unique house rental for you to enjoy a memorable holiday or a weekend with your family and friends.

What are the main cities to discover in Mississippi?

Whether you're traveling with family or friends, here are the cities with the largest selection of vacation rentals for a holiday trip or just for a weekend in Mississippi:

  • Gulfport: 803 rentals
  • Ocean Springs: 585 rentals
  • Biloxi: 795 rentals
  • Bay St Louis: 373 rentals
  • Pass Christian: 505 rentals

For other cities, please use our search bar to access the selection of vacation rentals available.