Santa Cruz vacation rentals

We found 200 vacation rentals — enter your dates for availability

Discover a selection of 21 homes, 184 apartments, and other vacation rentals in Santa Cruz that are perfect for your trip. Whether you're going on vacation with family or friends, vacation rentals have the amenities you need and want for your stay, including parking and a TV. You'll be sure to find a rental to meet everyone's needs, including options that are accessible or non-smoking.

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Find out more about Santa Cruz

Why visit Santa Cruz

  • Cultural Experiences: Santa Cruz boasts a rich cultural scene, with vibrant neighborhoods like San Diego and New Orleans showcasing local charm.
  • Outdoor Adventures: Explore beautiful nature reserves and nearby natural attractions, perfect for outdoor enthusiasts.
  • Family-Friendly Activities: The city offers a variety of fun activities suitable for families, ensuring everyone has a good time.
  • Relaxation Spots: Unwind on Oak Island, a serene location ideal for relaxation amidst nature.
  • Welcoming Hospitality: Experience the warmth and friendliness of the local Bolivian community during your visit.

Popular types of accommodation in Santa Cruz

Santa Cruz offers a diverse selection of vacation rentals, including cozy apartments and spacious private homes. Whether you're seeking monthly rentals or select hotels, you'll find options that fit your needs. Be sure to check out hotel photos and amenities like laundry facilities for added convenience. Explore our vacation rentals for a perfect getaway in Santa Cruz, where adventure and relaxation await.

  • Apartments: The most sought-after lodging option in Santa Cruz, offering a comfortable and convenient stay for travelers seeking a home-like atmosphere.
  • Houses: A popular choice for groups and families, these homes provide ample space and privacy, ensuring a relaxing getaway in Santa Cruz.**

Top attractions in Santa Cruz

Santa Cruz, Bolivia, offers a vibrant mix of city-themed, family-friendly, and cultural experiences. Visitors can explore popular attractions such as the lively piazza, the stunning cathedral, and the beautiful nature reserve. With a focus on culture, family activities, and outdoor adventures, there's something for everyone to enjoy in this dynamic city.

  • Plaza 24 de Septiembre: This vibrant square is the heart of Santa Cruz, surrounded by lively cafés and shops. It's a perfect spot to immerse yourself in local culture, enjoy street performances, and experience the city’s dynamic atmosphere.
  • San Lorenzo Cathedral: A stunning example of colonial architecture, this cathedral offers a peaceful retreat with its intricate designs and serene ambiance. It's a great place to appreciate local history and spirituality.
  • Blacutt Square: A popular landmark ideal for excursions, Blacutt Square features beautiful gardens and is often bustling with local events, making it a great spot to interact with residents and enjoy outdoor activities.

Things to do recommended for couples

Looking for a romantic getaway in Santa Cruz? Explore the lush Parque Nacional Amboró, enjoy a candlelit dinner at a rooftop restaurant, and take a leisurely walk through the vibrant streets of the city, immersing yourselves in the local culture and flavors together.

Things to do recommended for families

Families will love the vibrant Parque El Arenal, featuring a playground and picnic areas, or explore the interactive exhibits at the Museo de Historia Natural. Don't miss the beautiful Jardín Botánico, perfect for a leisurely stroll and enjoying nature together.

Things to do recommended for groups

Explore the vibrant markets of La Ramada, where you can sample local delicacies, or take a guided tour of the historic city center. For adventure, consider a day trip to Amboró National Park for hiking and wildlife spotting with your friends.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

What do I need to keep in mind when booking a vacation in Santa Cruz

If you're traveling with a group, with family, bringing pets, or planning an extended stay, be sure to apply the appropriate filters based on your priorities. Here are some helpful Vrbo booking tips for you.

  • Traveling to Santa Cruz with a group: Think about how many bedrooms you'll require, along with features like a full kitchen or outdoor area for group gatherings. Luckily, you can easily filter for all of these options and more on Vrbo.
  • Traveling to Santa Cruz with young kids: Traveling with young children can present its own set of challenges. It's important to prioritize their comfort and safety, along with suitable amenities like a private swimming pool. Additionally, it's wise to think about how close you are to family-friendly attractions.
  • Taking your pets with you to Santa Cruz: For many families, a vacation isn't truly complete without their furry companion by their side. If you can relate, explore Vrbo listings that welcome pets. Most pet-friendly properties come equipped with feeding bowls and beds, ensuring that everyone feels comfortable and at home.
  • Planning for a long term stay visiting Santa Cruz: If you're in search of vacation rentals that offer discounts for stays of a month or longer, you've come to the right spot. By using the appropriate filters, you can effortlessly discover and save on monthly rentals. Don't forget to include amenities like a parking space, a well-equipped kitchen, or a private pool in your search criteria as well.

Where to stay in and around Santa Cruz

Santa Cruz, Bolivia, offers a vibrant mix of culture, family-friendly activities, and urban exploration. Visitors can enjoy excursions to nearby natural features, discover the charm of neighborhoods like San Diego and New Orleans, or experience the lively atmosphere reminiscent of Las Vegas. Don't miss the opportunity to relax on Oak Island or immerse yourself in the warm hospitality of the locals. Santa Cruz promises a delightful blend of experiences for every traveler.

  • Colinas del Urubo: Nestled in the heart of Santa Cruz, Colinas del Urubo is a charming village renowned for its family-friendly atmosphere and vibrant city life. Visitors are drawn to this area for its blend of relaxation and entertainment, with easy access to shopping malls and resorts. One of its standout features is the nearby botanical garden, offering a lush escape for nature lovers. Colinas del Urubo is perfect for those looking to enjoy a mix of leisure activities and urban experiences, making it an ideal spot for both families and business travelers.
  • La Guardia: Located approximately 13 miles from Santa Cruz, La Guardia is a delightful city that invites visitors to explore its outdoor offerings and family-friendly environment. Known for its serene resorts, the area is perfect for those seeking relaxation amidst nature. Visitors can also take advantage of the local botanical garden, providing a picturesque backdrop for leisurely strolls. La Guardia serves as a great base for outdoor adventures and a quieter experience away from the bustling city.
  • Warnes: Situated 19 miles from Santa Cruz, Warnes is a vibrant city that offers a mix of outdoor fun and urban charm. Travelers come here seeking family-friendly experiences, with an array of resorts, shopping centers, and malls available for exploration. The city is also home to notable landmarks, including a beautiful botanical garden, a charming piazza square, and a historic cathedral. Warnes is an excellent destination for those wanting to balance leisure and cultural experiences during their vacation.

Best time to go to Santa Cruz

If you're planning a trip to Santa Cruz, it's a good idea to check both the weather and property rates. The warmest month is October. Peak season runs in January, July and September, while off-peak times, like May, October and December tend to have fewer bookings and better deals.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January78.3°F (25.7°C)Light RainMostly SunnySlightly HighAverage
February77.0°F (25.0°C)Light RainMostly CloudyAverageModerately High
March76.5°F (24.7°C)Light RainMostly SunnyAverageModerately High
April74.5°F (23.6°C)Light RainMostly SunnyAverageAverage
May70.2°F (21.2°C)Light RainMostly SunnySlightly LowAverage
June67.8°F (19.9°C)Light RainMostly SunnyAverageModerately High
July68.5°F (20.3°C)No Rain (Dry)Mostly SunnySlightly HighAverage
August72.9°F (22.7°C)No Rain (Dry)SunnyAverageModerately Low
September77.9°F (25.5°C)Light RainSunnySlightly HighModerately Low
October79.5°F (26.4°C)Light RainMostly SunnySlightly LowAverage
November79.3°F (26.3°C)Light RainMostly SunnyAverageAverage
December78.4°F (25.8°C)Light RainMostly SunnySlightly LowModerately Low

Booking with Vrbo is simple

Are you hoping to save money on your upcoming trip? Being flexible with your travel dates can make a big difference, as prices often fluctuate. Additionally, consider booking a longer stay to take advantage of potential savings. To discover a Vrbo property that suits your budget, feel free to use our filters to sort by price, location, and vacation rental type. We're here to help you find the perfect getaway.

Vrbo Trips: Effortless planning

Vrbo’s Trip Board offers an easy way to plan your journeys, allowing you to start new trips, continue from where you last left off, or manage your travel arrangements. You can view the properties you've saved or booked, organized into categories like Potential, Upcoming, or Current Trips. To begin using Trip Boards, simply visit: https://www.vrbo.com/trips.

**Based on Vrbo properties bookings.

Choose a vacation rental for your Santa Cruz getaway

Enjoy the cathedral and other features of Santa Cruz. Renowned for its shopping, cafes and zoo, this city welcomes all visitors. With a vacation rental, you get a home away from home. Many rentals offer full kitchens and outdoor grills for some home cooking.

Activities and attractions in and around Santa Cruz

Are you looking for attractions to visit in the city? Venture out of your vacation home and experience everything that makes Santa Cruz a fun place to get away. Here are some of the major attractions to explore, all within 30 miles (48.2 km) of the city center:

  • Santa Cruz Zoo (1.7 mi / 2.8 km)
  • Play Land Amusement Park (7.7 mi / 12.3 km)

Exploring the natural features in Santa Cruz

Whether you're looking for exciting outdoor activities or just want to take in the scenery, Santa Cruz is a great place to get outside. Here are a few of the area's most eye-catching sights, all within 30 miles (48.2 km) of the city center:

  • Arenal Park (0.5 mi / 0.8 km)
  • Guembe Biocenter (4.6 mi / 7.4 km)
  • Lomas de Arena Regional Park (10.7 mi / 17.1 km)
  • Municipal Botanical Garden of Santa Cruz (7.6 mi / 12.2 km)

How to get to and around Santa Cruz

The nearest airport is in Santa Cruz (SRZ-El Trompillo), located 1.2 mi (1.9 km) from the city center. If you can't find a flight that works for your travel itinerary, you could book a flight to Santa Cruz (VVI-Viru Viru Intl.), which is 9.8 mi (15.8 km) away.

If you prefer train travel, the main station is Santa Cruz de la Sierra Station.

Frequently asked questions

What is the best area to stay in Santa Cruz, Santa Cruz, Bolivia when booking a vacation rental?
When considering a vacation rental in Santa Cruz, Bolivia, one of the best areas to explore is the vibrant neighborhood surrounding the city center. This area offers a lively option with a variety of dining and shopping options. You can easily stroll through the bustling streets and enjoy the local culture. A top attraction in this area is the beautiful Plaza 24 de Septiembre, where you can relax in the park and take in the impressive architecture of the surrounding buildings. Additionally, the nearby Biocentro Guembe offers a fantastic opportunity to connect with nature, featuring a butterfly sanctuary and a variety of recreational activities.

Another excellent option is the Equipetrol neighborhood, known for its upscale ambiance and modern amenities. Here, you can discover an array of trendy restaurants and bars, superb for experiencing the local culinary scene. The nearby Ventura Mall is a popular destination for shopping, providing a mix of local and international brands, as well as entertainment options.

Overall, Santa Cruz has a diverse selection of properties available, suiting different tastes and budgets, making it an ideal destination for vacation rentals.
How much does it cost to rent a vacation home in Santa Cruz?
Prices for vacation rentals in Santa Cruz vary based on factors like travel dates, length of stay, accommodation type, and location. Simply enter your trip details to explore a wide range of options—whether you're traveling solo, as a couple, with family, or in a group. Vrbo offers something for every taste and budget, from affordable rentals in Santa Cruz to more spacious homes. To get the best value, book early and take advantage of Vrbo's free rewards program.
Are there any discounts for Santa Cruz vacation house rentals?
You can find great discounts on house rentals in Santa Cruz on Vrbo, including special rates on new listings and savings for weekly or monthly stays with top amenities such as a pool or parking. There are several discounts for Last minute bookings, and Early bird bookings too. The best part is, there's no need for a discount code—just enter your travel dates and apply the discount filters to view the top rates.
What is the most popular type of vacation rental accomodation in Santa Cruz?
In Santa Cruz, apartments are the most popular type of vacation rental, with about 151 available throughout the city. These apartments are typically located in bustling neighborhoods, providing easy access to local markets, restaurants, and parks. Most units come equipped with essential amenities such as fully equipped kitchens, comfortable living spaces, and often include air conditioning to cope with the warm climate.

For those seeking more space, there are around 16 vacation houses available, offering multiple bedrooms and outdoor areas great for family gatherings or group retreats. Additionally, several condos, houseboats, and chalets provide unique lodging options for travelers looking for something different.
Are there any family house rentals in Santa Cruz?
In Santa Cruz, Bolivia, there are numerous family-friendly house rentals available—specifically, around 37 options throughout the area. Visitors will find properties in various neighborhoods, each offering unique amenities and proximity to local attractions. Many homes feature spacious living areas, well-equipped kitchens, and outdoor spaces ideal for kids to play, ensuring a comfortable stay for families.

In addition to the appealing accommodations, the city itself offers a vibrant setting with parks and recreational areas nearby, great for family outings. Families can explore the local markets, enjoy delicious Bolivian cuisine, and immerse themselves in the rich culture of Santa Cruz.
Can I rent a vacation home with a pool or hot tub in Santa Cruz?
In Santa Cruz, Bolivia, there are plenty of vacation homes available for rent that feature pools and hot tubs, with around 83 options to choose from. The city is known for its vibrant culture and warm climate, making it an excellent destination for travelers seeking relaxation. Many properties are located in neighborhoods like Equipetrol and Urbarí, which are popular for their accessibility to local attractions and amenities.

Travelers can expect a variety of amenities in these rentals, including private pools, inviting hot tubs, spacious outdoor areas for lounging, and fully equipped kitchens great for meal preparation. Some properties may also offer extras such as barbecue grills and beautifully landscaped gardens, enhancing the overall vacation experience.
Can I find long-stay vacation rentals in Santa Cruz?
A long-stay vacation rental in Santa Cruz is the best way to experience local living. Plus, you can make the most of long-stay discounts. For month-long stays, save an average of 19%, and for week-long bookings you can save an average of 10%.* Long-stay discounts are applied automatically when you enter your vacation dates into the search tool, or you can use the "Weekly stay" and "Monthly stay" filters in your search.

*Based on analysis of Vrbo booking and occupancy data for 2024 stays.
Are there pet-friendly house rentals in Santa Cruz?
In Santa Cruz, travelers will find a variety of pet-friendly house rentals, with over 50 options available to suit different preferences and budgets. Many of these vacation rentals offer amenities such as spacious backyards, allowing pets to roam freely, as well as modern kitchens and comfortable living spaces for relaxation after a day of exploring the area.

The city itself is known for its parks and green spaces, which provide excellent opportunities for pet owners to enjoy outdoor activities with their furry companions. Locations like Parque El Arenal and Parque Urbano Central are popular spots where pets are welcome, making them ideal for leisurely strolls or picnics.
Are there any remote work vacation rentals in Santa Cruz?
In Santa Cruz, Bolivia, there are numerous vacation rentals that cater to remote workers, with around 115 options available throughout the city. These properties are well-equipped with essential amenities such as high-speed Wi-Fi, dedicated workspaces, and comfortable desks, ensuring a productive environment for those working remotely. Many rentals also offer additional conveniences like air conditioning and laundry facilities, making longer stays comfortable and straightforward.

The city provides a vibrant backdrop for remote work, with various cafes and co-working spaces nearby for those who prefer a change of scenery. Santa Cruz is known for its rich cultural scene, and after work hours, travelers can explore local markets, parks, and restaurants, providing a superb blend of work and leisure. To help narrow your search, insert your dates and apply the "WiFi" filter on Vrbo.
Are there any Santa Cruz vacation rentals with parking?
Vrbo offers a wide selection of vacation rentals in Santa Cruz with parking available—perfect for families or travelers who value the convenience of having a car during their stay. To easily find these properties, simply enter your travel details on Vrbo and use the "Parking available" filter under the amenities section. This makes it quick and easy to browse listings that suit your needs, whether you're planning a short city break or a longer stay.
What are popular rental amenities in Santa Cruz?
In Santa Cruz, vacation rentals often come equipped with a variety of amenities that enhance the stay for travelers. Many properties feature kitchens, allowing guests to prepare their own meals, which is a big plus for families or those looking to save on dining costs. Pets are permitted in several rentals, making it easier for pet owners to enjoy their vacation without leaving their furry friends behind. Onsite parking is commonly available, providing convenience for guests with vehicles. Additionally, fitness facilities are offered in some properties, suiting those who wish to maintain their workout routines while traveling. Outdoor pools are also a popular amenity, offering a refreshing escape from the warm Bolivian climate.
When is the best time to visit Santa Cruz for a vacation rental?
The best time to visit Santa Cruz for a vacation rental is during the peak season from July to September, with September being particularly popular among travelers. This vibrant period attracts visitors eager to experience the lively option of the city, where they can enjoy a mix of cultural events and outdoor activities.

During these months, temperatures are typically warm, ranging from the mid-60s to mid-80s Fahrenheit, creating an ideal climate for exploring Santa Cruz's rich history and beautiful parks. Whether you're wandering through the bustling markets or savoring local cuisine at outdoor cafes, the pleasant weather enhances your experience.

For those looking for a more budget-friendly option, consider visiting in May. This month offers a quieter ambiance, allowing you to enjoy the city's attractions without the crowds. You can still relish the welcoming climate and explore the lush landscapes that surround Santa Cruz.

Ultimately, your choice will depend on whether you prefer the energetic vibe of peak season or the peaceful charm of the shoulder month.
How early should I book a Santa Cruz vacation rental?
Book your Santa Cruz vacation rental at least two months before you travel for the best selection of properties.* Plus, you'll typically find that the earlier you book your vacation rental, the better the price.

*Based on analysis of Vrbo booking and occupancy data for 2024 stays.
What are the top attractions in Santa Cruz, Santa Cruz, Bolivia?
In Santa Cruz, travelers can explore a variety of attractions that showcase the city's culture and natural beauty. The Plaza 24 de Septiembre serves as the heart of the city, surrounded by historic buildings, vibrant markets, and outdoor cafes, making it a great starting point for visitors. Nearby, the Cathedral Metropolitana provides a glimpse of the city's architectural heritage.

The Biocentro Güembé is a popular attraction for families, featuring a butterfly garden, a small zoo, and a swimming pool area, all set in lush surroundings. For those interested in art and history, the Museo de Historia Natural Noel Kempff Mercado offers insights into the region's biodiversity and cultural history.

In the outskirts, the Lomas de Arena Regional Park offers unique sand dune landscapes and opportunities for outdoor activities like sandboarding and hiking, while the nearby Amboró National Park showcases diverse ecosystems and wildlife, ideal for nature enthusiasts.
Can I change or cancel my Santa Cruz home rental booking on Vrbo?
To find Santa Cruz vacation rentals with free cancellation, just use Vrbo's handy "Free cancellation" search filter. We get that plans can change, so it's easy to filter properties that give you flexibility. If you need to make changes to an existing booking, drop your host a message. Go to "My Trips" in your account, click "Change or Cancel" and then "Message Host". Vrbo rentals give you the privacy of having the entire place to yourself, and for extra flexibility, some travelers can choose to pay over time with Affirm. Whether you're adjusting your plans or looking for flexible payment options, Vrbo makes it easy to book with confidence.
Why should I join Vrbo as a host?
Joining Vrbo as a host opens the door to a global community of travelers seeking unique stays, giving you the opportunity to earn income from your property on your terms. With user-friendly tools, dedicated support, and exposure on major travel sites, Vrbo makes it easy to list, manage, and succeed. Whether it's a cozy cabin or a beach condo, you can turn your space into a standout destination, become a host and let Vrbo handle the heavy lifting to help you thrive.

Earn a Premier Host badge by providing quick, reliable communication and consistently delivering outstanding guest experiences.
Are all fees included in the Santa Cruz vacation rental prices shown on Vrbo?
Vrbo provides upfront pricing from the moment you start your search. There are no hidden fees added during the check-out process. This allows you to compare properties with ease and plan your trip with confidence.
What is VrboCare™ and how does it work?
Vrbo's mission is to help guests relax, reconnect, and enjoy precious time together. With VrboCare™, you can have peace of mind knowing you're protected and that if something goes wrong, we will do our best to make it right as applicable.

If a significant issue arises that your host can't resolve, we'll help you address it, find a similar property, or get your reservation refunded if applicable. That's our promise. If a home is significantly different than listed, we'll get you into a new space that meets your needs and makes it right, or if a host cancels before your stay, you have a dedicated support team to get you into a similar home as applicable.
What can I expect from Vrbo customer service and VrboCare™ support?
Your peace of mind is our priority. Whether you're planning your trip or have already finished your stay, VrboCare™ is here to support you every step of the way. For urgent situations like last-minute cancellations, booking issues, or potential fraud, Vrbo customer service is available 24/7 to help resolve problems quickly and effectively.

Vrbo also offers support via live chat through our Help Center, where you can find helpful resources on bookings, payments, property management, and safety, making it easy to get instant answers to many common questions.
Can I plan a group trip on Vrbo?
Vrbo's Trip Planner makes organizing group trips easy and stress-free. Whether you're planning with friends or coordinating a large group, you can collaborate in one place, save and share properties, vote on favorites, and build the perfect itinerary together.

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