Manasota vacation rentals
We found 180 vacation rentals — enter your dates for availability
Discover a selection of 51 homes and other vacation rentals in Manasota that are perfect for your trip. Whether you’re staying in a vacation home with family or friends, you'll find the best amenities for hanging out with the people that matter most, such as parking and air conditioning. Whatever you're looking for, you'll find a rental that has what everyone needs, including a place that's non-smoking or offers accessibility.
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Find the best place to stay - Manasota
Beachfront Home on Gulf of Mexico w/ Indoor Pool
Sleeps 6 · 3 bedrooms · 3 bathrooms
Seaclusion - stunning bayfront home with pool
Sleeps 10 · 4 bedrooms · 3 bathrooms
6 minute walk to Manasota Beach! POOL! Charming 2-bedroom townhome with WiFi, AC
Sleeps 6 · 2 bedrooms · 1 bathroom
Lemoness -- 4 bedrooms, 3 baths, heated pool, 1/2 mile from Manasota Key Beach!
Sleeps 12 · 4 bedrooms · 3 bathrooms
Old Florida Charm, quiet, close to beach and boat launch.
Sleeps 10 · 4 bedrooms · 2 bathrooms
Charming 3-bedroom Home, minutes to Manasota Beach
Sleeps 6 · 3 bedrooms · 2 bathrooms
Top rated rentals - Manasota
Wonderful
Wonderful rental home, we really enjoyed our stay. Lesley is great, makes for a stress free experience.
Bethany M.
Stayed Dec 2025
Perfect!
We’ve been coming to TMI houses for many, many years (20?) and have only praise for every one. “Bliss” certainly is a family fave. Lesley & Doreen are great to work with and a pleasure to visit with each time. 5 stars all around!
Lawrence C.
Stayed Aug 2025
Jungle cottage
We had a great time at the Jungle cottage. The house was equipped with everything we needed and was beautiful. The location was very close to beautiful Manasota beach.
Mallory B.
Stayed May 2025
Vacation Dream
We had the best time and it was a beautiful home. Great access to everything, but still secluded.
Anita F.
Stayed Oct 2024
Vacation
We had a wonderful time at the Shell house. It’s centrally located to a lot of beaches that are all beautiful. The house very clean and has all the amenities that you need. Every time I was needing something I would look around and there it was. I would definitely recommend the Shell House.
Greene, C.
Stayed Jun 2024
Lovely home
Enjoyed our stay.
marisa V.
Stayed Jun 2024
Most Restful
This was a beautiful home, right on the bay. The view was gorgeous. This house is close to the beach and stores. The house was clean and everyone was happy.
Kristy F.
Stayed May 2021
Peace of mindOur Book with Confidence guarantee gives you 24/7 support
All the privacy of homeEnjoy full kitchens, laundry, pools, yards and more
More for lessMore space, more privacy, more amenities — more value
Frequently asked questions
Are there vacation rentals in Manasota?
Yes, there are vacation rentals close to the most popular attractions in Manasota, or you can select a more remote option if you're looking for relaxation.
How many vacation rentals are there in Manasota?
Expedia has 51 vacation rentals for your stay in Manasota.
What can I see and do in Manasota?
While exploring the area, visit family-friendly sights like Jim Neville Marine Preserve, or get outside and enjoy nature at Lemon Bay. In the larger area, you'll find Manasota Beach and Blind Pass Beach.
What are vacation rentals like in Manasota?
Vacation rentals are privately owned properties you can reserve for several days or more in Manasota. Vacation rentals feature amenities like kitchens and laundry facilities so you'll feel right at home. If you're concerned about a clean environment, vacation rentals can provide a sense of privacy away from public hotel elevators and busy concierge desks while still allowing you the enjoyment of travel. You'll also find more space in a vacation rental than in a hotel, which is another reason why a vacation rental is an attractive option for family gatherings.