Santa Ana vacation rentals

We found 110 vacation rentals — enter your dates for availability

Scroll through and select from vacation rentals in Santa Ana to find one that's perfect for your trip. Vacation homes provide the best amenities for your family, friends, or furry companion, like WiFi and parking. At the end of the day, you'll find a rental that has what everyone needs, including a place that's non-smoking or offers accessibility.
  • Peace of mind

    Our Book with Confidence guarantee gives you 24/7 support
  • All the privacy of home

    Enjoy full kitchens, laundry, pools, yards and more
  • More for less

    More space, more privacy, more amenities — more value
  • A place for everyone

    We stand for diversity, inclusion and families everywhere.
    Learn more

Find out more about Santa Ana

Why visit Santa Ana

  • Rich Cultural Heritage: Explore historic buildings and archaeological sites that showcase Guatemala's captivating past.
  • Scenic Outdoor Activities: Enjoy breathtaking landscapes perfect for hiking and romantic getaways.
  • Charming Neighborhood Vibe: Wander through picturesque cobblestone streets filled with local culture and charm.
  • Delicious Local Cuisine: Savor authentic Guatemalan dishes at various local eateries.
  • Convenient Base for Exploration: Use Santa Ana as a launching point to discover nearby attractions like Antigua Guatemala.

Popular types of accommodation around Santa Ana

If you're exploring vacation rentals in Santa Ana, you're in for a treat. Our top choices include houses, cozy apartments, and luxurious villas. Whether you're looking for a whole home in Santa Ana or a charming villa, we have a variety of options to suit your needs. Enjoy your stay with the best accommodations Santa Ana has to offer, providing comfort and convenience for every traveler.

  • Houses: The top choice for visitors in Santa Ana, offering spacious and comfortable accommodations perfect for families or groups.
  • Apartments: A popular option, providing convenient and cozy living spaces ideal for solo travelers or couples.
  • Villas: These luxurious dwellings offer beautiful surroundings and private amenities for a lavish getaway.
  • Condos: A favored selection that combines comfort and community living, perfect for short or extended stays.
  • Chalets: A charming choice that provides a unique and rustic atmosphere, ideal for those seeking a cozy retreat.**

Top attractions near Santa Ana

Santa Ana, Antigua Guatemala, is perfect for outdoor enthusiasts and romantic getaways, offering a blend of scenic beauty and cultural richness. Visitors can explore historic buildings, archaeological sites, and urban parks, making it ideal for families and city explorers alike. Don't miss the chance to visit Antigua Guatemala, a nearby gem filled with captivating history and vibrant culture, ensuring a memorable vacation experience.

  • Central Park: A vibrant urban oasis, Central Park offers a family-friendly atmosphere with lush greenery, local vendors, and a bustling scene perfect for relaxation and people-watching.
  • Antigua Guatemala Cathedral: This stunning cathedral showcases remarkable colonial architecture and rich cultural heritage, making it a must-visit for history buffs and architecture enthusiasts.
  • Casa Santo Domingo Museum: Set in a former convent, this museum features fascinating archaeological and anthropological exhibits that delve into the region's history, offering a unique cultural experience.

Things to do recommended for couples

Experience romance in Santa Ana, Antigua Guatemala, by exploring the charming cobblestone streets hand-in-hand. Enjoy a candlelit dinner at a local restaurant, followed by a sunset view from the Cerro de la Cruz. Don't miss a tranquil coffee plantation tour for a unique taste of Guatemalan culture.

Things to do recommended for families

Families visiting Santa Ana can explore the vibrant local markets, hike the scenic trails of the nearby volcanoes, or enjoy a cultural experience at the historic sites. Don’t miss the chance to taste delicious Guatemalan cuisine at family-friendly restaurants.

Things to do recommended for groups

Explore the vibrant local markets in Santa Ana, where you can sample traditional Guatemalan dishes and shop for handmade crafts. Join a guided tour of the stunning Pacaya Volcano for breathtaking views, or participate in a colorful weaving workshop to learn about local textile traditions.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

What do I need to keep in mind when booking a vacation around Santa Ana

When planning your trip—whether you're traveling with a group, family, pets, or looking for extended stays—be sure to prioritize your preferences when filtering your options. Here are some helpful Vrbo booking tips for you.

  • Traveling to Santa Ana with a group: Think about how many bedrooms you'll require, as well as features like a fully equipped kitchen or outdoor areas for group gatherings. Luckily, you can easily filter for these options and more on Vrbo.
  • Traveling to Santa Ana with young kids: Traveling with young kids can present its own set of challenges. It's important to prioritize their comfort and safety, along with finding age-appropriate amenities like a private swimming pool. Additionally, it's wise to think about how close you are to attractions that cater to families.
  • Taking your pets with you to Santa Ana: For many, a family vacation wouldn't be the same without their furry companions. If you can relate to this, explore Vrbo listings that welcome pets. Many of these pet-friendly properties offer feeding bowls and beds, ensuring that everyone feels comfortable and at home.
  • Planning for a long term stay visiting Santa Ana: If you're in search of vacation rentals that offer special rates for stays of a month or more, you've come to the right spot. By using the appropriate filter, you can effortlessly discover and save on monthly rentals. You might also want to include options like a parking space, a well-equipped kitchen, or a private pool in your search criteria.

Where to stay near Santa Ana

Santa Ana, nestled in Antigua Guatemala, offers a delightful blend of historical charm and vibrant culture. This picturesque neighborhood is perfect for outdoor enthusiasts and romantic getaways, with breathtaking scenery and a rich atmosphere. Explore the nearby cities and regions, where you'll discover the captivating heritage of Guatemala. Whether you're wandering through cobblestone streets or enjoying local cuisine, Santa Ana provides a convenient base for an unforgettable travel experience.

  • Antigua Guatemala: Nestled in a picturesque valley, Antigua Guatemala is a vibrant city renowned for its well-preserved Spanish Baroque architecture and stunning volcanic backdrop. Travelers flock to this historic city for its outdoor adventures, breathtaking scenery, and romantic ambiance. Don't miss exploring local markets filled with colorful handicrafts and delicious street food, as well as the captivating museums that showcase the city’s rich history. Key attractions include the serene views of Lake Antigua and archaeological sites that provide a glimpse into the region's past.
  • Historic Center: Located a mere 0.9 miles from Santa Ana, the Historic Center is the heart of Antigua Guatemala. This charming neighborhood enchants visitors with its cobblestone streets, vibrant plazas, and stunning colonial architecture. It offers a variety of outdoor experiences, making it an ideal spot for romantic strolls. Explore the bustling public market for local crafts and delicious Guatemalan cuisine, and be sure to visit the iconic cathedral and fascinating museums that dot the area. The nearby lake adds to the picturesque scenery, making it a perfect backdrop for memorable photographs.
  • Barrio de La Concepción: Situated just 0.7 miles from Santa Ana, Barrio de La Concepción is a culturally rich neighborhood that invites exploration. This area is known for its outdoor beauty and scenic vistas, providing an authentic taste of local life. The neighborhood features vibrant shopping areas where you can find unique souvenirs and artisanal products. Key attractions nearby include intriguing museums and archaeological sites that delve into the region's history, as well as the tranquil lake that offers a peaceful escape from the bustling city life.

Booking with Vrbo is a breeze

Are you hoping to save on your upcoming trip? Being flexible with your travel dates can make a difference, as prices often fluctuate. Additionally, booking an extended stay can lead to considerable savings. To discover a Vrbo property that aligns with your budget, feel free to use our filters to sort by price, location, and type of vacation rental. We're here to help you find the perfect getaway.

Vrbo Trips: Effortless planning

Vrbo’s Trip Board provides a convenient area to plan new trips, manage your travel arrangements, or revisit and organize your reservations. Your saved or booked properties are now categorized into Potential, Upcoming, or Current Trips for easy access. To check out Trip Boards, please visit: https://www.vrbo.com/trips.

**Based on Vrbo properties bookings.

Frequently asked questions

What is the most popular type of vacation rental in Santa Ana?
In Santa Ana, vacation houses, villas, and cottages are the most popular types of rentals, with several options available throughout the area. These properties typically feature spacious interiors, fully equipped kitchens, and comfortable living spaces, making them suitable for families or groups. Many properties also offer outdoor areas, great for enjoying the pleasant climate and beautiful surroundings of Sacatepéquez.
How much does it cost to rent a vacation home in Santa Ana?
Prices for vacation rentals in Santa Ana vary based on factors like travel dates, length of stay, accommodation type, and location. Simply enter your trip details to explore a wide range of options—whether you're traveling solo, as a couple, with family, or in a group. Vrbo offers something for every taste and budget, from affordable rentals in Santa Ana to more spacious homes. To get the best value, book early and take advantage of Vrbo's free rewards program.
Are there any discounts for Santa Ana vacation house rentals?
You can find great discounts on house rentals in Santa Ana on Vrbo, including special rates on new listings and savings for weekly or monthly stays with top amenities such as a pool or parking. There are several discounts for Last minute bookings, and Early bird bookings too. The best part is, there's no need for a discount code—just enter your travel dates and apply the discount filters to view the top rates.
What are popular rental amenities in Santa Ana?
In Santa Ana, Guatemala, popular vacation rental amenities include fully equipped kitchens, allowing travelers to prepare their own meals. Many rentals also feature balconies or patios, providing a lovely space to enjoy the fresh air and scenic views. Cozy fireplaces are commonly found in these properties, great for creating a warm and inviting atmosphere during cooler evenings. Additionally, travelers can expect coffee and tea makers in many units, ensuring a convenient way to start the day.
Can I find family house rentals in Santa Ana?
In Santa Ana, Sacatepéquez, there are several family-friendly house rentals available, making it a great choice for groups looking to explore the area. Many of these homes provide spacious living areas, fully equipped kitchens for preparing meals together, and outdoor spaces superb for children to play. Visitors can expect amenities such as Wi-Fi and comfortable accommodations to enhance their stay.

The town is set against a beautiful backdrop of mountains, offering opportunities for hikes and outdoor activities. Nearby attractions include the charming town of Antigua, known for its historic architecture and vibrant markets, which is just a short drive away.
Can I rent a vacation home with a pool or hot tub in Santa Ana?
In Santa Ana, Sacatepéquez, travelers can find several vacation homes available for rent that feature pools and hot tubs. This charming area offers a picturesque setting with stunning views of the surrounding hills and volcanoes. Many properties come equipped with private pools, hot tubs, and outdoor terraces, providing a superb space for relaxation and enjoyment.

Additionally, travelers can expect amenities like fully equipped kitchens, spacious living areas, and sometimes even game rooms or outdoor dining spaces, making these rentals ideal for families or groups seeking comfort and leisure during their stay. Find your rental in Santa Ana with a pool or a hot tub.
Are there any Santa Ana vacation rentals with parking?
Vrbo offers a wide selection of vacation rentals in Santa Ana with parking available—perfect for families or travelers who value the convenience of having a car during their stay. To easily find these properties, simply enter your travel details on Vrbo and use the "Parking available" filter under the amenities section. This makes it quick and easy to browse listings that suit your needs, whether you're planning a short city break or a longer stay.
Can I find long-stay vacation rentals in Santa Ana?
A long-stay vacation rental in Santa Ana is the best way to experience local living. Plus, you can make the most of long-stay discounts. For month-long stays, save an average of 19%, and for week-long bookings you can save an average of 10%.* Long-stay discounts are applied automatically when you enter your vacation dates into the search tool, or you can use the "Weekly stay" and "Monthly stay" filters in your search.

*Based on analysis of Vrbo booking and occupancy data for 2024 stays.
When is the best time to visit Santa Ana for a vacation rental?
The best time to visit Santa Ana, Sacatepéquez, is during the peak season from February to April, when visitors can take part in the vibrant culture and stunning landscapes of the region. These months are characterized by pleasant temperatures ranging from the mid-60s to low 80s Fahrenheit, providing ideal conditions for outdoor activities such as hiking the nearby volcanoes and exploring the charming historic architecture of the town.

June is particularly popular among travelers, as it offers a lively option and an opportunity to experience local festivals and events. Although this month can bring occasional rain, it also showcases the lush greenery of the region, making it an excellent time for photography and exploration.

For those seeking a more budget-friendly option, consider planning your trip in October. This month presents a quieter experience, allowing for intimate exploration without the bustling crowds. Visitors can appreciate the beautiful fall foliage and enjoy scenic walks, all while still benefiting from comfortable temperatures.

Ultimately, the best time to book a vacation rental in Santa Ana depends on your preferences for cultural experiences and outdoor adventures.
Are there any remote work vacation rentals in Santa Ana?
In Santa Ana, Sacatepéquez, there are several vacation rentals suitable for remote work. These properties typically offer essential amenities such as reliable internet, Wi-Fi in rooms, and safety features like in-room safes, ensuring a secure and productive environment for guests. The area is known for its scenic views and proximity to cultural attractions, making it an appealing choice for those looking to balance work and leisure. To help narrow your search, insert your dates and apply the "WiFi" filter on Vrbo.
How early should I book a Santa Ana vacation rental?
Book your Santa Ana vacation rental at least two months before you travel for the best selection of properties.* Plus, you'll typically find that the earlier you book your vacation rental, the better the price.

*Based on analysis of Vrbo booking and occupancy data for 2024 stays.
What are the top attractions in Santa Ana, Sacatepéquez, Guatemala?
In Santa Ana, Sacatepéquez, travelers can immerse themselves in the rich cultural heritage and stunning natural landscapes. The town is renowned for its vibrant local markets, where visitors can find traditional crafts and local produce. The Santa Ana Church, with its striking architecture, is a must-see landmark that reflects the town's historic history.

Just a short distance from the town center, the Santa Ana Volcano offers hiking opportunities for those looking to experience breathtaking views and unique geological features. Nearby, the picturesque Lake Coatepeque is a popular spot for relaxation and water activities, making it a great destination for outdoor enthusiasts.

In addition to these attractions, the surrounding areas are dotted with charming villages and coffee plantations, providing visitors a taste of the local culture and agricultural heritage.
Can I change or cancel my Santa Ana home rental booking on Vrbo?
To find Santa Ana vacation rentals with free cancellation, just use Vrbo's handy "Free cancellation" search filter. We get that plans can change, so it's easy to filter properties that give you flexibility. If you need to make changes to an existing booking, drop your host a message. Go to "My Trips" in your account, click "Change or Cancel" and then "Message Host". Vrbo rentals give you the privacy of having the entire place to yourself, and for extra flexibility, some travelers can choose to pay over time with Affirm. Whether you're adjusting your plans or looking for flexible payment options, Vrbo makes it easy to book with confidence.
Why should I join Vrbo as a host?
Joining Vrbo as a host opens the door to a global community of travelers seeking unique stays, giving you the opportunity to earn income from your property on your terms. With user-friendly tools, dedicated support, and exposure on major travel sites, Vrbo makes it easy to list, manage, and succeed. Whether it's a cozy cabin or a beach condo, you can turn your space into a standout destination, become a host and let Vrbo handle the heavy lifting to help you thrive.

Earn a Premier Host badge by providing quick, reliable communication and consistently delivering outstanding guest experiences.
Are all fees included in the Santa Ana vacation rental prices shown on Vrbo?
Vrbo provides upfront pricing from the moment you start your search. There are no hidden fees added during the check-out process. This allows you to compare properties with ease and plan your trip with confidence.
What is VrboCare™ and how does it work?
Vrbo's mission is to help guests relax, reconnect, and enjoy precious time together. With VrboCare™, you can have peace of mind knowing you're protected and that if something goes wrong, we will do our best to make it right as applicable.

If a significant issue arises that your host can't resolve, we'll help you address it, find a similar property, or get your reservation refunded if applicable. That's our promise. If a home is significantly different than listed, we'll get you into a new space that meets your needs and makes it right, or if a host cancels before your stay, you have a dedicated support team to get you into a similar home as applicable.
What can I expect from Vrbo customer service and VrboCare™ support?
Your peace of mind is our priority. Whether you're planning your trip or have already finished your stay, VrboCare™ is here to support you every step of the way. For urgent situations like last-minute cancellations, booking issues, or potential fraud, Vrbo customer service is available 24/7 to help resolve problems quickly and effectively.

Vrbo also offers support via live chat through our Help Center, where you can find helpful resources on bookings, payments, property management, and safety, making it easy to get instant answers to many common questions.
Can I plan a group trip on Vrbo?
Vrbo's Trip Planner makes organizing group trips easy and stress-free. Whether you're planning with friends or coordinating a large group, you can collaborate in one place, save and share properties, vote on favorites, and build the perfect itinerary together.

More Vacation Ideas