Photo by TM
Uptown District vacation rentals
We found 129 vacation rentals — enter your dates for availability
Welcome to the vibrant Uptown District, where urban parks meet cultural gems and history intertwines with modernity. This lively destination boasts diverse attractions—from the engaging exhibits at COSI to the artistic treasures of the Columbus Museum of Art—ensuring unforgettable experiences for families and groups alike. With stylish apartments, cozy cabins, and spacious vacation homes at your disposal, you'll relish the comfort and convenience of a home away from home while exploring all that this dynamic area has to offer.
Find spaces that suit your style
House
Condo/Apartment
Find properties near top attractions in Uptown District
Map Attractions
Find the best place to stay - Uptown District

Jenny's Palace In The Heart of Columbus!
Sleeps 12 · 4 bedrooms · 2+ bathrooms
9.0 out of 10
wonderful
(17 reviews)
Top rated rentals - Uptown District

Cute modern stay!
10 out of 10
exceptional
(89 reviews)
The rooms were very clean! Very cute place to stay at!
Eloisa
Stayed Sep 2025
- Peace of mindOur Book with Confidence guarantee gives you 24/7 support
- All the privacy of homeEnjoy full kitchens, laundry, pools, yards and more
- More for lessMore space, more privacy, more amenities — more value
Frequently asked questions
More Vacation Ideas
- Discovery District Vacation Rentals
- Galloway Vacation Rentals
- Heritage Rail Trail Vacation Rentals
- Pataskala Vacation Rentals
- Grove City Vacation Rentals
- Groveport Vacation Rentals
- University District Vacation Rentals
- New Albany Vacation Rentals
- Downtown Columbus Vacation Rentals
- Central Ohio Vacation Rentals
- Turkey Run Vacation Rentals
- German Village Vacation Rentals
- Schiller Park Vacation Rentals
- Obetz Vacation Rentals
- Lewis Center Vacation Rentals
- Shawnee Hills Vacation Rentals
- Plain City Vacation Rentals
- Blacklick Vacation Rentals
- The Hocking Hills Vacation Rentals
- Dublin Vacation Rentals
- Short North Vacation Rentals
- South Columbus Vacation Rentals
- Grandview Heights Vacation Rentals
- Powell Vacation Rentals
- Galena Vacation Rentals
- Reynoldsburg Vacation Rentals
- Westerville Vacation Rentals
- Hilliard Vacation Rentals
- North Columbus Vacation Rentals
- Nationwide Arena Vacation Rentals
- Columbus Vacation Rentals
- Columbus Vacation Rentals
- East Columbus Vacation Rentals
- Zaleski State Forest Vacation Rentals
- Lockbourne Vacation Rentals
- Southeast Ohio Vacation Rentals
- Pickerington Vacation Rentals
- Canal Winchester Vacation Rentals
- Weinland Park Vacation Rentals
- Victorian Village Vacation Rentals
- Chalet rentals in The Hocking Hills
- Pet-Friendly rentals in Dublin
- Rentals with pool in Logan
- Pet-Friendly rentals in Buckeye Lake
- Family rentals in Buckeye Lake
- Pet-Friendly rentals in Gahanna
- Lake rentals in Howard
- Rentals with hot tubs in The Hocking Hills
- Mansion rentals in Upper Arlington
- Farm rentals in The Hocking Hills
- Lodge rentals in Hideaway Hills
- Longstay Rentals in Lewis Center
- Lodge rentals in Granville
- Guest houses in Columbus
- Pet-Friendly rentals in Sunbury
- Family rentals in The Hocking Hills
- Cabin rentals in Central Ohio
- Family rentals in Logan
- Beach rentals in Mount Vernon
- Longstay Rentals in Columbus
- Longstay Rentals in West Jefferson
- Rentals with pool in University District
- Beach rentals in The Hocking Hills
- Lake rentals in Southeast Ohio
- Condo rentals in Short North
- Rentals with hot tubs in South Bloomingville
- Family rentals in Yellow Springs
- Ski-In/Ski-Out rentals in Zaleski State Forest
- Longstay Rentals in Dublin
- Rentals with hot tubs in Central Ohio
- Longstay Rentals in Westerville
- Rentals with pool in Columbus
- Rentals with hot tubs in Logan
- House rentals in Columbus
- Beach rentals in Zaleski State Forest
- House rentals in Grandview Heights
- Family rentals in South Bloomingville
- Pet-Friendly rentals in Columbus
- Rentals with pool in Buckeye Lake
- Cottage rentals in Columbus
- Pet-Friendly rentals in Grove City
- Townhouse rentals in Short North
- Condo rentals in Columbus
- Lake rentals in The Hocking Hills
- Family rentals in Columbus
- Hotels in Zaleski State Forest
- Rentals with pool in The Hocking Hills
- Townhouse rentals in Columbus
- Guest houses in Worthington
- Bed and breakfasts in Rockbridge
- Lake rentals in Logan
- Rentals with hot tubs in Columbus
- Longstay Rentals in Pataskala
- Rentals with pool in South Bloomingville
- Rv and caravan rentals in Zaleski State Forest
- Cottage rentals in Buckeye Lake
- Cabin rentals in Columbus
- Mountain rentals in Zaleski State Forest
- Beach rentals in Central Ohio
- Lake rentals in Buckeye Lake












