~ Deaconess Guesthouse: Iconic Riverfront Luxury · Panoramic Ohio River Views · Minutes from Dtn Louisville / Dtn Jeffersonville ~
★ A Landmark Estate Reimagined for Elevated Living
Perched along the banks of the Ohio River, Deaconess Guesthouse is a rare riverfront estate where historic grandeur meets modern luxury. Once Jeffersonville’s first public hospital, this meticulously restored 1800s landmark has been transformed into a refined retreat that blends architectural heritage with boutique-hotel sophistication.
Thoughtfully curated by Charming Vacation Homes, every detail—from the craftsmanship to the furnishings—has been designed to deliver an experience of comfort, elegance and effortless luxury, all framed by sweeping river views and a prime waterfront setting.
Just steps from Jeffersonville’s vibrant riverfront and only minutes from Downtown Louisville, Churchill Downs and the Bourbon Trail, Deaconess Guesthouse offers the perfect balance of serenity and city access.
★ Designed for Exceptional Stays & Memorable Gatherings
The estate features 8 beautifully designed bedrooms and 6 spa-inspired bathrooms across four private suites, comfortably accommodating up to 24 guests. Ideal for:
- Executive and corporate retreats
- Multi-family vacations
- Wedding parties and milestone celebrations
- Holiday gatherings and private events
Each space is intentionally styled with premium furnishings, custom artwork, layered textures, and warm, inviting finishes—creating an atmosphere that feels both luxurious and welcoming.
★ Signature Amenities & One-of-a-Kind Features
1. Private Hot Tub & Fire Pit – Unwind riverside beneath open skies after a day of exploring.
2. Wraparound Porches & Balconies – Perfect for sunrise coffee, sunset cocktails, and uninterrupted river views.
3. Stargazing Dome – A whimsical, unforgettable hideaway loved by kids, creatives, and couples alike.
4. Ample On-Site Parking – A rare and valuable amenity for large groups and event-focused stays.
★ An Unmatched Location
- Walk to Downtown Jeffersonville – Dining, boutique shopping, festivals, and seasonal riverfront events just steps away.
- Minutes to Downtown Louisville – Distilleries, museums, concert venues, sports arenas, and nightlife within easy reach.
- Outdoor Adventures at Your Doorstep – Paddle-boarding, biking paths and scenic riverfront trails surround the property.
★ Where Moments Become Memories
Whether you’re soaking in the hot tub beneath the stars, gathering around the fire pit as riverboats glide past, or sharing long conversations on the porch overlooking the water, Deaconess Guesthouse invites you to slow down, reconnect and savor the experience.
This is more than a place to stay—it’s a setting designed for connection, celebration and unforgettable moments.
★ Now Booking Luxury Stays & Private Events
Perfect for:
- Executive retreats and leadership offsites
- Family reunions and group getaways
- Weddings, anniversaries, and milestone celebrations
- Holiday stays and weekend escapes
Reserve your stay at one of the region’s most distinctive riverfront estates—where history, luxury, and meaningful experiences come together.
★ CONVENIENT LOCATION
The house is centrally located and is within a 10-15 minute Uber/Lyft drive to most locations:
- Churchill Downs (DERBY) - 7.7 miles (15 mins)
- Big Four Walking Bridge (Connecting KY and IN) - 0.4 miles (2 mins)
- KFC Yum Center - 2.3 miles (7 mins)
- Downtown Louisville/ 4th Street Live - 2.4 miles (6 mins)
- Waterfront Park - 3.4 miles (9 mins)
- Papa Johns Stadium (Cardinal Stadium) - 6.4 miles (11 mins)
- Kentucky Fairgrounds - 6.5 miles (10 min)
- University of Louisville - 6.5 miles (12 mins)
- Kentucky Exposition Center - 6.7 miles (11 mins)
- Kentucky Kingdom - 7.4 miles (13 mins)
- Highland Festival Grounds - 8.5 miles (12 mins)
- Louisville Airport - 8.6 miles (10 mins)
- Louisville Mega Cavern - 10.2 miles (19 mins)
- UPS Worldport - 11.2 miles (20 mins)
- Ford LAP Plant - 10.9 miles (16 mins)
- Waverly Hills Sanatorium - 17 miles (30 mins)
- Valhalla Golf Club - 19 miles (27 mins)
PROPERTY HIGHLIGHTS
★ Panoramic Riverfront Views: Wake to sweeping Ohio River views and stunning sunrises, with downtown Jeffersonville and Louisville just minutes away for dining, shopping and entertainment.
★ Historic Charm, Modern Luxury: A beautifully restored landmark blending timeless architecture with elegant, contemporary design and curated furnishings.
★ Serene Outdoor Living: Enjoy coffee or cocktails on covered porches and private balconies overlooking the river.
★ Comfort for Groups: Eight stylish bedrooms and six spa-like bathrooms, plus bright living spaces designed for gathering and relaxing.
★ Gourmet Kitchens: Four fully equipped kitchens with premium appliances make meals and celebrations effortless.
★ Family & Pet Friendly: Thoughtful spaces and amenities for kids and pets so everyone feels at home.
★ Private Outdoor Oasis: Hot tub, riverfront fire pit, gazebo/Hyperdome dining and lawn games for memorable outdoor moments.
★ Entertainment Ready: Multiple lounges, Smart TVs and indoor/outdoor games for easy fun.
★ Perfect for Retreats & Celebrations: Ideal for reunions, retreats and special occasions with ample parking and in-home laundry.
★ A Signature Riverfront Stay: Historic elegance, modern comfort and an unbeatable riverfront setting—crafted for an unforgettable getaway.
★ 2026 TOP EVENTS
- CROSS 2026 – Jan 1, 2026
- A Salute to the Rat Pack – Jan 2–3, 2026
- Trevor Wallace – Jan 9, 2026
- Harlem Globetrotters – Jan 16, 2026
- Neko Case – Jan 20, 2026
- Dinosaur World Live – Jan 23, 2026
- Candlelight: Coldplay & Imagine Dragons – Jan 23, 2026
- The Millennium Tour – Jan 23, 2026
- Bluegrass World of Wheels – Jan 24–25, 2026
- NouLou Chamber Players – Feb 2, 2026
- Black Violin – Feb 5, 2026
- The Great Gatsby – Feb 10–15, 2026
- Gary Owen – Feb 13, 2026
- Kinetic Light – Feb 14, 2026
- Cody Johnson – Feb 14, 2026
- Kindle the Flame – Feb 14, 2026
- NEEDTOBREATHE (Acoustic) – Feb 17, 2026
- Saxsquatch – Feb 20, 2026
- Growers Not Showers Party – Feb 21, 2026
- USA Gymnastics Winter Cup – Feb 20–22, 2026
- John Crist – Feb 22, 2026
- moe. – Feb 22, 2026
- Bourbon Classic – Feb 25–28, 2026
- The Lone Bellow – Feb 25, 2026
- LDB Fest – Feb 27–28, 2026
- Josiah Queen – Mar 7, 2026
- NouLou Chamber Players (Schubertiade) – Mar 9, 2026
- Sweet Honey in the Rock – Mar 29, 2026
- America: Happy Trails Tour – Apr 2, 2026
- Chelsea Handler – Apr 12, 2026
- Thunder Over Louisville – Apr 18, 2026
- Brandon Lake – Apr 24, 2026
- Great Steamboat Race – Apr 29, 2026
- Kentucky Oaks – May 1, 2026
- Kentucky Derby – May 2, 2026
- The Invaders – May 11, 2026
- World Oddities Expo – Jun 13–14, 2026
- Forrest Frank – Jul 28, 2026
- Kentucky State Fair – Aug 20–30, 2026
- Ray LaMontagne – Sep 6, 2026
- Big Four Art Festival – Sep 12–13, 2026
- Louder Than Life – Sep 17–20, 2026
- Bourbon & Beyond – Sep 24–27, 2026
- St. James Court Art Show – Oct 3–4, 2026
- NuLu Fest – Oct 9–11, 2026
- Halloween & Haunted Attractions – Oct 24–31, 2026
- Thanksgiving Week Travel – Nov 25–29, 2026
- Light Up Louisville – Nov 27, 2026
- Christmas at Frazier Museum – Dec 5–20, 2026
- Louisville Ballet: The Nutcracker – Dec 2026
- New Year’s Eve at Fourth Street Live! – Dec 31, 2026
★ 2026 TRADE SHOWS & EXPOS
- North American Honey Bee Expo — Jan 8–10, 2026
- Louisville Home + Garden Show — Jan 9–11, 2026
- Louisville Manufactured Housing Show — Jan 14–16, 2026
- NVP Product Expo — Jan 22–25, 2026
- Louisville Boat, RV & Sportshow — Jan 28–Feb 1, 2026
- Show of Shows (Military Antiques) — Jan 29–Feb 1, 2026
- National Farm Machinery Show — Feb 11–14, 2026
- Ace Hardware Spring Convention — Feb 24–26, 2026
- GAMA Expo — Mar 1–5, 2026
- Mid-America Trucking Show (MATS) — Mar 26–28, 2026
- Connect Spring Marketplace — Apr 14–16, 2026
- World Oddities Expo — Jun 13–14, 2026
- Equip Expo — Oct 20–23, 2026
★ OPTIONAL CONCIERGE ENHANCEMENTS
Make your stay even more effortless:
✔ Grocery Pre-Stocking – Walk into a fully prepared kitchen.
✔ Private Chef Experience – Perfect for celebrations or elevated evenings in.
✔ Custom Bourbon Tours & Chauffeur Services – Personalized for your group.
★ PEACE OF MIND AND EXCEPTIONAL GUEST COMFORT
✔ Professionally cleaned and sanitized
✔ Contactless self check-in for your convenience
✔ 24/7 guest support throughout your stay
✔ Exterior-only security cameras at the front of the home for guest safety and property protection
NOTE:
1. 25+ to book.
2. House Rules Required: E-sign rental agreement and submit a $500 security hold via secure OwnerRez (placed 2 days before arrival, released 7 days after departure if no damage).
3. Strict cancellation for Derby & Bourbon & Beyond dates.
4. No visitors unless pre-approved by the host.
5. Exterior cameras only (parking area & front door). No interior or backyard cameras.
6. Dome use: Not recommended during hot summer months.
7. No early check-in / late check-out on same-day turnovers.
8. When available: $100 (≤2 hrs), $250 (2–4 hrs), full night rate (>4 hrs).
9. Non-Airbnb refunds incur a 3% Stripe processing fee.
PLEASE REVIEW THE HOUSE RULES BEFORE BOOKING. THANKS!