Sant' Ambrogio vacation rentals
We found 2,725 vacation rentals — enter your dates for availability
Discover a selection of 209 apartments and other vacation rentals in Sant' Ambrogio that are perfect for your trip. Whether you're staying in a vacation rental with a group or just with your pet, you'll have the amenities you expect and more, which might include air conditioning and a pool. You'll be sure to find a rental for everyone's needs, including options that are accessible or non-smoking.
Holiday rentals with weekly discounts - Sant' Ambrogio
Showing deals for:Nov 6 - Nov 13

Exceptional
(17 reviews)
newly renovated amazing apt close to DUOMO, WI-FI, A / C
Florence
$304
$2,127 for 7 nights
All fees included

Exceptional
(42 reviews)
Fortress Apartament with Parking
Florence
$151
$1,059 for 7 nights
All fees included

Exceptional
(45 reviews)
APARTMENT WITH 2-BEDROOM IN THE HISTORIC CENTER + PRIVATE PARKING
Florence
$151
$1,060 for 7 nights
All fees included

Exceptional
(18 reviews)
A small romantic apartment in the heart of Florence
Florence
$133
$928 for 7 nights
All fees included

Exceptional
(41 reviews)
Beautiful apartment sleeps in the city centre of Florence
Florence
$197
$1,382 for 7 nights
All fees included

Exceptional
(91 reviews)
X-Large and luxury apartment in the old town! - All comfort -
Florence
$743
$5,198 for 7 nights
All fees included

Wonderful
(30 reviews)
Centrally located apartment, all attractions within walking distance
Florence
$153
$1,068 for 7 nights
All fees included

Exceptional
(108 reviews)
BRIGHT LOFT IN THE HEART OF FLORENCE A FEW STEPS FROM UFFIZZI
Florence
$151
$1,059 for 7 nights
All fees included

Exceptional
(61 reviews)
Spacious and charming apartment in the heart of Florence
Florence
$333
$2,330 for 7 nights
All fees included

Exceptional
(23 reviews)
Stunning view over Ponte Vecchio
Florence
$391
$2,738 for 7 nights
All fees included

Exceptional
(51 reviews)
DANTE ROOF TERRACE HOUSE
Florence
$497
$3,482 for 7 nights
All fees included

Exceptional
(34 reviews)
Apartment overlooking the Duomo
Florence
$211
$1,476 for 7 nights
All fees included

Exceptional
(10 reviews)
Uffizi SuiteLarge and elegant renovated apartment in the heart of Florence
Florence
$465
$3,255 for 7 nights
All fees included

Exceptional
(11 reviews)
Bright Apartment a few steps from Duomo and Train Station. Wifi, A/C, W&D
Florence
$253
$1,771 for 7 nights
All fees included

Exceptional
(87 reviews)
'Grande Pepi', Luxury Apartment in Florence Centre!(AC, Wifi,..)
Florence
$454
$3,181 for 7 nights
All fees included

Exceptional
(21 reviews)
★Steps from Uffizi Gallery★Spacious 3BR Apartment★
Florence
$295
$2,068 for 7 nights
All fees included

Wonderful
(45 reviews)
Apartment in the center, all sights are within walking distance
Florence
$137
$958 for 7 nights
All fees included

Exceptional
(149 reviews)
A Few Steps From Duomo Cathedral and SMN train station
Florence
$231
$1,615 for 7 nights
All fees included

Exceptional
(68 reviews)
'Piccolo Pepi' - Luxury Apartment in the Heart of Florence!
Florence
$338
$2,363 for 7 nights
All fees included

Exceptional
(60 reviews)
Panoramic penthouse on the river 2Br 2 Ba Garage
Florence
$191
$1,338 for 7 nights
All fees included

Exceptional
(8 reviews)
David Sweet Suite
Florence
$180
$1,262 for 7 nights
All fees included

Exceptional
(12 reviews)
Apartment LaCosta near Ponte Vecchio
Florence
$180
$1,260 for 7 nights
All fees included

Exceptional
(142 reviews)
Just a few minutes from the Cathedral and the most beautiful Monuments in town
Florence
$72
$503 for 7 nights
All fees included

Exceptional
(140 reviews)
DUOMO, your private garden in TORRE: THE SFINGE OF THE SECRET GARDEN.
Florence
$213
$1,489 for 7 nights
All fees included
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Find the best place to stay - Sant' Ambrogio

Modern Murate View in Florence by Mmega
Sleeps 6 · 2 bedrooms · 2 bathrooms

YID Agnolo three bedroom apartment in Florence
Sleeps 8 · 3 bedrooms · 3 bathrooms

Bright and wide, wonderful apt in the center of the city
Sleeps 8 · 5 bedrooms · 3 bathrooms

Independent 50 meters from the central and very Tuscan Duomo
Sleeps 3 · 1 bedroom · 1 bathroom
Top rated rentals - Sant' Ambrogio

Amazing Location and Wonderful Accommodations
Property was impeccably maintained and offered style and comfort beyond our expectations. The location was near groceries and all the sights Florence offers. We even explored more local environments where we felt part of the community. I would stay here over and over again.
Garri R.
Stayed Jun 2025

Fabulous stay in Florence
We had a wonderful time in Florence.Alessandro was an awesome communicator!Restaurants, shopping & food were all very close by. Definitely pack your good walking shoes; there’s so much to see!
Pamela G.
Stayed Apr 2025

Lovely stay in Florence
We had a wonderful stay, our hosts were gracious and introduced us to everything we would need. Would love to return here again and book 2 apartments for our family.
Rebecca M.
Stayed Oct 2024

Perfect location, top notch apartment.
The home feels newly renovated and decorated. Very clean and we loved that the immediate neighborhood felt less busy and touristy but we still could easily walk to attractions and the main train station downtown. Would absolutely stay here again. Recommend highly.
Scott L.
Stayed Jun 2024

Clean and well stocked
This apartment is clean and well stocked. Quiet building, pictures are accurate. 20 minutes walk from the train station. Will stay again.
Lai N.
Stayed Dec 2023

Florentine aerie
Silvia was the perfect hostess, welcoming, informative, and, I think, even arranged the weather. We enjoyed the Sant’Ambroglio neighborhood, lively, but not overrun with tourists and proximate to all we toured. The open market was a treat, and the neighborhood restaurants authentic after a day of touring. The apartment was very clean and outfitted with all amenities we would need for our three day stay. The second bedroom is creatively designed, but we managed very well.
Amy M.
Stayed Oct 2023

The reviews are correct!
What an awesome experience in Florence, or our little piece of it! This unit is located on the north side of the river on a little pedestrian street that has a gelato shop, a few cafe's and down the road, one of the best pizzas we have had. Say Ciao to my dog friend Spena if you see him! The roads are a bit confusing but after 4 tries, we have the path to the leather school down! We didn't do any tours, sorry, but the host Silvia was there with every answer to my questions or issues I had. The place was darling, spacious and SUPER clean, even though there were sometimes crowds on the street, it was super quiet in the unit, she said bc of double paned windows. The Italians know how to do everything right and our stay was really nice, bought a LOT of goods at the leather school, which is a must see and ate and drank and napped every day. Felt very safe everywhere we went, even when we got lost in the parks at night. Stayed 5 nights, I truly think what made it so much better and stress free was our host Silvia. If I could give her 6 stars I would!
jan b.
Stayed Sep 2023

Fantastic property and location
Our family of 4 stay in the property for a week in July 2023 and it was perfect and very welcoming. It was clean and plenty of room for us. The location was so great if we needed to come ‘home’ mid day to take a break from the heat and all the exploring. Beds were comfortable. Loved the keyless entry - so conventions. We needed to reach the host upon arrival and he was very accommodating . So glad we chose this properly and would book again in the future
Amy V.
Stayed Jul 2023
- Peace of mindOur Book with Confidence guarantee gives you 24/7 support
- All the privacy of homeEnjoy full kitchens, laundry, pools, yards and more
- More for lessMore space, more privacy, more amenities — more value
Frequently asked questions
How much does it cost to rent a vacation home in Sant' Ambrogio?
Prices for vacation rentals in Sant' Ambrogio vary based on factors like travel dates, length of stay, accommodation type, and location. Simply enter your trip details to explore a wide range of options—whether you're traveling solo, as a couple, with family, or in a group. Vrbo offers something for every taste and budget, from affordable rentals in Sant' Ambrogio to more spacious homes. To get the best value, book early and take advantage of Vrbo's free rewards program.
Are there any discounts for Sant' Ambrogio vacation house rentals?
You can find great discounts on house rentals in Sant' Ambrogio on Vrbo, including special rates on new listings and savings for weekly or monthly stays with top amenities such as a pool or parking. There are several discounts for Last minute bookings, and Early bird bookings too. The best part is, there's no need for a discount code—just enter your travel dates and apply the discount filters to view the top rates.
Are there any Sant' Ambrogio vacation rentals with parking?
Vrbo offers a wide selection of vacation rentals in Sant' Ambrogio with parking available—perfect for families or travelers who value the convenience of having a car during their stay. To easily find these properties, simply enter your travel details on Vrbo and use the "Parking available" filter under the amenities section. This makes it quick and easy to browse listings that suit your needs, whether you're planning a short city break or a longer stay.
Can I find long-stay vacation rentals in Sant' Ambrogio?
A long-stay vacation rental in Sant' Ambrogio is the best way to experience local living. Plus, you can make the most of long-stay discounts. For month-long stays, save an average of 19%, and for week-long bookings you can save an average of 10%.* Long-stay discounts are applied automatically when you enter your vacation dates into the search tool, or you can use the "Weekly stay" and "Monthly stay" filters in your search.
*Based on analysis of Vrbo booking and occupancy data for 2024 stays.
When is the best time to visit Sant' Ambrogio for a vacation rental?
The most popular time to visit Sant' Ambrogio is in September, when the summer heat begins to mellow and the vineyards are alive with the grape harvest. This month offers an ideal blend of warm temperatures, typically in the mid-70s to low 80s Fahrenheit, superb for exploring the picturesque Tuscan countryside and indulging in wine tastings at local wineries.The peak tourist season runs from July to September, attracting travelers eager to experience the vibrant culture, stunning landscapes, and delicious cuisine that this charming region has to offer. Visitors during these months can partake in outdoor activities like hiking and cycling along scenic trails or enjoy leisurely strolls through the quaint streets adorned with historic architecture.For those seeking a more tranquil experience, November presents a wonderful opportunity to visit Sant' Ambrogio at a lower cost, while still enjoying the beauty of the area. The autumn foliage creates a captivating backdrop for exploration, and the cooler temperatures in the 50s to low 60s Fahrenheit provide a refreshing atmosphere for sightseeing.Ultimately, deciding when to book a vacation rental in Sant' Ambrogio depends on your preferences for lively summer festivities versus the peaceful charm of the shoulder season.
How early should I book a Sant' Ambrogio vacation rental?
Book your Sant' Ambrogio vacation rental at least two months before you travel for the best selection of properties.* Plus, you'll typically find that the earlier you book your vacation rental, the better the price.
*Based on analysis of Vrbo booking and occupancy data for 2024 stays.
What are the top attractions in Sant' Ambrogio, Tuscany, Italy?
In Sant' Ambrogio, travelers can immerse themselves in the rich history and stunning landscapes of Tuscany. The area is known for its picturesque countryside and charming medieval architecture, making it a superb base for exploring local attractions. Just a short distance away, visitors can explore the iconic town of Florence, where they can admire masterpieces such as the Duomo and the Uffizi Gallery.Closer to Sant' Ambrogio, the nearby town of Fiesole offers breathtaking views of Florence and is home to ancient Roman ruins and the beautiful Fiesole Cathedral. The lush hills surrounding Sant' Ambrogio are dotted with vineyards and olive groves, providing opportunities for wine tasting and leisurely walks through the scenic landscape.For those interested in art and culture, the nearby town of San Gimignano is famous for its medieval towers and is a UNESCO World Heritage site, showcasing stunning frescoes in its churches.
Can I change or cancel my Sant' Ambrogio home rental booking on Vrbo?
To find Sant' Ambrogio vacation rentals with free cancellation, just use Vrbo's handy "Free cancellation" search filter. We get that plans can change, so it's easy to filter properties that give you flexibility. If you need to make changes to an existing booking, drop your host a message. Go to "My Trips" in your account, click "Change or Cancel" and then "Message Host". Vrbo rentals give you the privacy of having the entire place to yourself, and for extra flexibility, some travelers can choose to pay over time with Affirm. Whether you're adjusting your plans or looking for flexible payment options, Vrbo makes it easy to book with confidence.
Why should I join Vrbo as a host?
Joining Vrbo as a host opens the door to a global community of travelers seeking unique stays, giving you the opportunity to earn income from your property on your terms. With user-friendly tools, dedicated support, and exposure on major travel sites, Vrbo makes it easy to list, manage, and succeed. Whether it's a cozy cabin or a beach condo, you can turn your space into a standout destination, become a host and let Vrbo handle the heavy lifting to help you thrive.
Earn a Premier Host badge by providing quick, reliable communication and consistently delivering outstanding guest experiences.
Are all fees included in the Sant' Ambrogio vacation rental prices shown on Vrbo?
Vrbo provides upfront pricing from the moment you start your search. There are no hidden fees added during the check-out process. This allows you to compare properties with ease and plan your trip with confidence.
What is VrboCare™ and how does it work?
Vrbo's mission is to help guests relax, reconnect, and enjoy precious time together. With VrboCare™, you can have peace of mind knowing you're protected and that if something goes wrong, we will do our best to make it right as applicable.
If a significant issue arises that your host can't resolve, we'll help you address it, find a similar property, or get your reservation refunded if applicable. That's our promise. If a home is significantly different than listed, we'll get you into a new space that meets your needs and makes it right, or if a host cancels before your stay, you have a dedicated support team to get you into a similar home as applicable.
What can I expect from Vrbo customer service and VrboCare™ support?
Your peace of mind is our priority. Whether you're planning your trip or have already finished your stay, VrboCare™ is here to support you every step of the way. For urgent situations like last-minute cancellations, booking issues, or potential fraud, Vrbo customer service is available 24/7 to help resolve problems quickly and effectively.
Vrbo also offers support via live chat through our Help Center, where you can find helpful resources on bookings, payments, property management, and safety, making it easy to get instant answers to many common questions.
Can I plan a group trip on Vrbo?
Vrbo's Trip Planner makes organizing group trips easy and stress-free. Whether you're planning with friends or coordinating a large group, you can collaborate in one place, save and share properties, vote on favorites, and build the perfect itinerary together.
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