Mayo Clinic vacation rentals

We found 27 vacation rentals — enter your dates for availability

Scroll through and select from vacation rentals in Mayo Clinic to find one that's perfect for your trip. Whether you're staying in a vacation rental with a group or just with your pet, you'll have the best amenities for spending time at your home away from home, which might include WiFi and a hot tub. What you'll find is a rental for everyone's needs, including options that are accessible or non-smoking.

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Find out more about Mayo Clinic

Why visit Mayo Clinic

  • Exceptional healthcare: Experience the world-renowned medical services at Mayo Clinic Hospital, known for its expert care.
  • Outdoor activities: Enjoy family-friendly adventures in urban parks and nearby mountains for relaxation and exploration.
  • Cultural experiences: Discover vibrant downtown Phoenix, featuring diverse dining and shopping options.
  • Scenic landscapes: Visit Fountain Hills for breathtaking views and outdoor pursuits, including its famous fountain.
  • Variety of accommodations: Choose from cozy rentals to luxurious resorts that cater to all travelers.

Popular types of accommodation around Mayo Clinic

Vrbo offers a variety of vacation rentals near Mayo Clinic, perfect for your stay. Whether you prefer houses, condos, or apartments, we have options to suit your needs. Many rentals come equipped with essential amenities like fitness centers and pool access, along with detailed floor plans to help you choose the ideal space. Find the perfect accommodation for your trip and enjoy a comfortable, convenient stay while visiting Mayo Clinic.

  • Houses: The top choice for travelers, offering spacious and comfortable settings ideal for families, friends, or couples visiting Mayo Clinic.
  • Condos: A popular option for those seeking modern amenities and convenient locations, perfect for shorter stays near Mayo Clinic.
  • Apartments: A favored selection for visitors looking for home-like comforts and flexibility during their time in Mayo Clinic.
  • Villas: A luxurious choice, providing stylish accommodations with added privacy for a relaxing retreat close to Mayo Clinic.
  • Cottages: A charming option for those who prefer a cozy, secluded atmosphere while still being near Mayo Clinic.**

Top attractions near Mayo Clinic

Mayo Clinic in Scottsdale, Arizona, offers a perfect blend of business-themed and family-friendly outdoor activities. Visitors can explore urban parks, attend conferences, and enjoy the nearby mountains. This destination caters to those seeking cultural experiences and outdoor adventures. Don't miss the renowned Mayo Clinic Hospital, which adds to the area's unique charm. Whether traveling solo or with family, there's always something exciting to discover around Mayo Clinic.

  • Westworld of Scottsdale: This vibrant event and conference venue is perfect for business travelers, featuring modern facilities and a dynamic atmosphere, making it a hub for various events and exhibitions.
  • Camelback Mountain: A must-visit for outdoor enthusiasts, this iconic mountain offers breathtaking views and exhilarating hiking trails, providing an unforgettable adventure in the heart of Arizona's natural beauty.
  • Fountain Hills Fountain: One of the tallest fountains in the world, this stunning attraction is set in a picturesque park, ideal for leisurely strolls and enjoying the vibrant city atmosphere.

Things to do recommended for couples

Searching for a romantic getaway near Mayo Clinic? Enjoy a captivating concert at the Scottsdale Center for the Performing Arts, indulge in luxury at the Scottsdale Gun Club, or savor a delightful meal at Rawhide Western Town & Steakhouse, perfect for a cozy couple's evening.

Things to do recommended for families

Your family will love the excitement at Salt River Fields for sports, unwind at Scottsdale Ranch Park for relaxation, and have a blast at Great Wolf Lodge Water Park for adventure—all within a short drive from Mayo Clinic, making it perfect for a memorable family vacation.

Things to do recommended for groups

Explore Kierland Commons for shopping and entertainment, just 8 miles from Mayo Clinic. Enjoy a round of golf at TPC Scottsdale Champions Course, 7 miles away, or engage in some fun at Scottsdale Ranch Park Tennis Center, located 4 miles from the clinic.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

What do I need to keep in mind when booking a vacation around Mayo Clinic

If you’re traveling with a group, bringing your family or pets, or planning an extended stay, be sure to prioritize your preferences when searching. Here are some helpful tips for booking on Vrbo.

  • Traveling to Mayo Clinic with a group: Think about how many bedrooms you'll require, along with features like a full kitchen or outdoor areas for group gatherings. Thankfully, you can easily refine your search for all these options and more on Vrbo.
  • Traveling to Mayo Clinic with young kids: Traveling with little ones can be quite a challenge. It's important to prioritize their comfort and safety, along with suitable amenities like a private swimming pool. Additionally, think about how close you are to family-friendly attractions.
  • Taking your pets with you to Mayo Clinic: For many families, a getaway isn’t truly fulfilling without their furry companion by their side. If you can relate, explore Vrbo listings that welcome pets. Many of these pet-friendly accommodations offer feeding bowls and beds, ensuring that everyone feels comfortable and at home.
  • Planning for a long term stay visiting Mayo Clinic: If you're in search of vacation rentals that offer discounts for stays of a month or more, you've come to the perfect spot. By using the appropriate filters, you can effortlessly discover and save on monthly rentals. Don't forget to include features like a parking space, a well-equipped kitchen, or a private pool in your search criteria as well.

Where to stay near Mayo Clinic

Exploring the Mayo Clinic area in Scottsdale, Arizona, offers a delightful blend of family-friendly activities and relaxing escapes. With diverse housing options, you'll find everything from cozy rentals to luxurious resorts. Don't miss the vibrant downtown Phoenix, perfect for dining and shopping, and the stunning landscapes of Fountain Hills, known for its picturesque fountain and outdoor adventures. This neighborhood is ideal for both business travelers and vacationers seeking memorable excursions.

  • Phoenix: As a sprawling metropolis, Phoenix serves as the vibrant backdrop for your visit to Mayo Clinic. Known for its family-friendly atmosphere and outdoor adventures, travelers flock here to enjoy a mix of urban and natural attractions. Explore the extensive shopping centers and malls, or take in a game at one of the impressive stadiums that dot the cityscape. For those keen on education, the modern college university campuses are worth a visit, offering a glimpse into the local culture and community.
  • Scottsdale: Scottsdale, another city that houses Mayo Clinic, is renowned for its blend of family, business, and city-themed experiences. The area boasts a variety of shopping malls and centers, perfect for indulging in retail therapy. Golf enthusiasts will appreciate the numerous golf courses available, while sports fans can catch events at local stadiums and conference venues. Scottsdale's vibrant atmosphere makes it a great destination for both leisure and business travelers alike.
  • Mirage Mountain: Located just 0.4 miles from Mayo Clinic, Mirage Mountain is a charming neighborhood appealing to those seeking a business-oriented, outdoor, and sports experience. Here, you can enjoy the amenities of a private country club or indulge in rejuvenating body treatments. The nearby golf course offers a perfect outing for enthusiasts, while event conference venues and research facilities add a distinct touch to this serene neighborhood, making it an ideal spot for both relaxation and productivity.

Best time to go to Mayo Clinic

If you're planning a trip to Mayo Clinic, it's a good idea to check both the weather and property rates. The warmest month is July. Peak season runs from January to March, while off-peak times, like May to June and August tend to have fewer bookings and better deals.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January55.4°F (13.0°C)No Rain (Dry)SunnySlightly HighAverage
February58.6°F (14.8°C)No Rain (Dry)SunnySlightly HighAverage
March66.0°F (18.9°C)No Rain (Dry)SunnySlightly HighSlightly High
April74.5°F (23.6°C)No Rain (Dry)SunnyAverageSlightly High
May82.0°F (27.8°C)No Rain (Dry)SunnySlightly LowAverage
June92.3°F (33.5°C)No Rain (Dry)SunnySlightly LowSlightly Low
July95.7°F (35.4°C)No Rain (Dry)SunnyAverageSlightly Low
August94.8°F (34.9°C)No Rain (Dry)SunnySlightly LowSlightly Low
September89.8°F (32.1°C)No Rain (Dry)SunnyAverageAverage
October77.7°F (25.4°C)No Rain (Dry)SunnyAverageAverage
November65.5°F (18.6°C)No Rain (Dry)SunnyAverageAverage
December55.4°F (13.0°C)No Rain (Dry)SunnyAverageSlightly High

Booking with Vrbo is a breeze

Are you hoping to save on your next adventure? Staying flexible with your travel dates can really pay off, as prices tend to vary. Additionally, booking a longer stay often leads to significant savings. To discover the perfect Vrbo property that fits your budget, utilize our filters to narrow down options by price, location, and type of vacation rental. We're here to support you in making the most of your travel experience.

Vrbo Trips: Planning made easy

Vrbo's exciting Trip Board feature allows you to plan your journeys seamlessly. You can create new trips, pick up right where you left off, or easily view and manage your travel plans. All the properties you've saved and booked can now be accessed under Potential, Upcoming, or Current Trips. To get started with Trip Boards, simply visit: https://www.vrbo.com/trips.

**Based on Vrbo properties bookings.

Frequently asked questions

What is the most popular type of vacation rental in Mayo Clinic?
In the Mayo Clinic area, vacation houses and cottages are the most popular types of rentals, with several options available. These properties typically feature spacious layouts, multiple bedrooms, and fully equipped kitchens, making them ideal for families or groups seeking comfort during their stay. Many also include outdoor spaces, such as patios or gardens, great for relaxation after a busy day at the clinic.
How much does it cost to rent a vacation home in Mayo Clinic?
Prices for vacation rentals in Mayo Clinic vary based on factors like travel dates, length of stay, accommodation type, and location. Simply enter your trip details to explore a wide range of options—whether you're traveling solo, as a couple, with family, or in a group. Vrbo offers something for every taste and budget, from affordable rentals in Mayo Clinic to more spacious homes. To get the best value, book early and take advantage of Vrbo's free rewards program.
Are there any discounts for Mayo Clinic vacation house rentals?
You can find great discounts on house rentals in Mayo Clinic on Vrbo, including special rates on new listings and savings for weekly or monthly stays with top amenities such as a pool or parking. There are several discounts for Last minute bookings, and Early bird bookings too. The best part is, there's no need for a discount code—just enter your travel dates and apply the discount filters to view the top rates.
What are popular rental amenities in Mayo Clinic?
In the vicinity of the Mayo Clinic in Arizona, vacation rentals often include a variety of desirable amenities to cater to travelers' needs. Most properties come equipped with fully functional kitchens, allowing guests to prepare their own meals. Many rentals also feature cozy fireplaces, superb for adding warmth during cooler evenings. Outdoor spaces, such as patios, are common, providing a nice area for relaxation or socializing. Additionally, many rentals in this area are pet-friendly, welcoming furry companions, and accommodate service animals, making it easier for those who require assistance during their stay.
Can I find family house rentals in Mayo Clinic?
In the vicinity of the Mayo Clinic in Arizona, there are several family-friendly vacation rentals available. The neighborhoods around the clinic, particularly in areas like Scottsdale and Phoenix, offer a variety of spacious homes that cater to families. Many of these properties feature multiple bedrooms, large living areas, and full kitchens, making it easy for families to enjoy home-cooked meals together.

Additionally, visitors can find amenities such as private pools and outdoor spaces where children can play. The proximity to parks and recreational areas provides opportunities for outdoor activities, while local attractions like the Desert Botanical Garden and the Phoenix Zoo are within a short drive, ensuring a fun and fulfilling stay for families visiting the Mayo Clinic.
Can I rent a vacation home with a pool or hot tub in Mayo Clinic?
In the vicinity of the Mayo Clinic in Arizona, travelers can find several vacation homes available for rent that feature both pools and hot tubs. The area is primarily residential, with properties scattered throughout nearby neighborhoods, offering convenient access to the clinic. Many of these rentals come equipped with private pools, hot tubs, and outdoor spaces ideal for relaxation after a day of appointments or exploring the local area. Additionally, travelers can expect amenities such as fully equipped kitchens, spacious living areas, and sometimes even outdoor grills or lounges, making for a comfortable and enjoyable stay.
Are there any Mayo Clinic vacation rentals with parking?
Vrbo offers a wide selection of vacation rentals in Mayo Clinic with parking available—perfect for families or travelers who value the convenience of having a car during their stay. To easily find these properties, simply enter your travel details on Vrbo and use the "Parking available" filter under the amenities section. This makes it quick and easy to browse listings that suit your needs, whether you're planning a short city break or a longer stay.
Can I book pet-friendly vacation rentals in Mayo Clinic?
In the vicinity of the Mayo Clinic in Arizona, several pet-friendly vacation rentals are available, making it convenient for travelers who wish to bring their furry companions. These rentals typically offer amenities such as spacious living areas, fully equipped kitchens, and private outdoor spaces where pets can enjoy the fresh air. Many properties in this area are designed with comfort in mind and include features like laundry facilities and Wi-Fi, ensuring a pleasant stay.

The surrounding neighborhoods provide easy access to parks and walking trails, great for pet owners, allowing for enjoyable outings with pets.
Can I find long-stay vacation rentals in Mayo Clinic?
A long-stay vacation rental in Mayo Clinic is the best way to experience local living. Plus, you can make the most of long-stay discounts. For month-long stays, save an average of 19%, and for week-long bookings you can save an average of 10%.* Long-stay discounts are applied automatically when you enter your vacation dates into the search tool, or you can use the "Weekly stay" and "Monthly stay" filters in your search.

*Based on analysis of Vrbo booking and occupancy data for 2024 stays.
Are there any remote work vacation rentals in Mayo Clinic?
In the vicinity of the Mayo Clinic in Arizona, there are several remote work-friendly vacation rentals available. Many of these accommodations come equipped with essential amenities for professionals, including dedicated workspaces with desk chairs, high-speed Wi-Fi, and business-themed environments that cater to productivity. Travelers can expect comfortable living spaces that allow for a seamless blend of work and relaxation.

The area surrounding the Mayo Clinic offers convenient access to local amenities like restaurants and shops, enhancing the overall experience for those balancing work and leisure. Additionally, some rentals may provide services such as limousine or town car transportation, further adding to the convenience of your stay. To help narrow your search, insert your dates and apply the "WiFi" filter on Vrbo.
How early should I book a Mayo Clinic vacation rental?
Book your Mayo Clinic vacation rental at least two months before you travel for the best selection of properties.* Plus, you'll typically find that the earlier you book your vacation rental, the better the price.

*Based on analysis of Vrbo booking and occupancy data for 2024 stays.
What are the top attractions in Mayo Clinic, Arizona, United States of America?
In Mayo Clinic, Arizona, visitors can explore a variety of attractions nearby. The clinic itself is well-known not only for its medical excellence but also for its beautiful grounds, which offer a peaceful environment. Just a short drive away, the Desert Ridge Marketplace provides a lively option with shopping, dining, and entertainment options.

For those interested in outdoor activities, the nearby Sonoran Desert offers stunning landscapes and hiking opportunities. The Phoenix Mountain Preserve is also accessible, featuring trails that offer breathtaking views of the city and surrounding mountains.

Additionally, the area is close to the vibrant neighborhoods of Scottsdale, where visitors can enjoy art galleries, upscale shopping, and a lively nightlife scene.
Can I change or cancel my Mayo Clinic home rental booking on Vrbo?
To find Mayo Clinic vacation rentals with free cancellation, just use Vrbo's handy "Free cancellation" search filter. We get that plans can change, so it's easy to filter properties that give you flexibility. If you need to make changes to an existing booking, drop your host a message. Go to "My Trips" in your account, click "Change or Cancel" and then "Message Host". Vrbo rentals give you the privacy of having the entire place to yourself, and for extra flexibility, some travelers can choose to pay over time with Affirm. Whether you're adjusting your plans or looking for flexible payment options, Vrbo makes it easy to book with confidence.
Why should I join Vrbo as a host?
Joining Vrbo as a host opens the door to a global community of travelers seeking unique stays, giving you the opportunity to earn income from your property on your terms. With user-friendly tools, dedicated support, and exposure on major travel sites, Vrbo makes it easy to list, manage, and succeed. Whether it's a cozy cabin or a beach condo, you can turn your space into a standout destination, become a host and let Vrbo handle the heavy lifting to help you thrive.

Earn a Premier Host badge by providing quick, reliable communication and consistently delivering outstanding guest experiences.
Are all fees included in the Mayo Clinic vacation rental prices shown on Vrbo?
Vrbo provides upfront pricing from the moment you start your search. There are no hidden fees added during the check-out process. This allows you to compare properties with ease and plan your trip with confidence.
What is VrboCare™ and how does it work?
Vrbo's mission is to help guests relax, reconnect, and enjoy precious time together. With VrboCare™, you can have peace of mind knowing you're protected and that if something goes wrong, we will do our best to make it right as applicable.

If a significant issue arises that your host can't resolve, we'll help you address it, find a similar property, or get your reservation refunded if applicable. That's our promise. If a home is significantly different than listed, we'll get you into a new space that meets your needs and makes it right, or if a host cancels before your stay, you have a dedicated support team to get you into a similar home as applicable.
What can I expect from Vrbo customer service and VrboCare™ support?
Your peace of mind is our priority. Whether you're planning your trip or have already finished your stay, VrboCare™ is here to support you every step of the way. For urgent situations like last-minute cancellations, booking issues, or potential fraud, Vrbo customer service is available 24/7 to help resolve problems quickly and effectively.

Vrbo also offers support via live chat through our Help Center, where you can find helpful resources on bookings, payments, property management, and safety, making it easy to get instant answers to many common questions.
Can I plan a group trip on Vrbo?
Vrbo's Trip Planner makes organizing group trips easy and stress-free. Whether you're planning with friends or coordinating a large group, you can collaborate in one place, save and share properties, vote on favorites, and build the perfect itinerary together.

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