DeSoto County Vacation Rentals, Mississippi: house rentals & more

Discover a selection of 63 homes and other vacation rentals in DeSoto County that are perfect for your trip. Whether you’re staying in a vacation home with family, friends, or just your furry companion, you'll find the best amenities for hanging out with the people that matter most, which might include a pool and a washer and dryer. Whatever you're looking for, you're sure to find a rental for everyone's needs, including a place that's non-smoking or offers accessibility.

Find spaces that suit your style

Find the best place to stay - DeSoto County

Cozy Highrise 2 br Apt - Downtown Memphis!

2 bedrooms · 1 bathroom

2 bedroom 2 bath pet friendly home in walkable hip Cooper Young neighborhood.

Sleeps 6 · 2 bedrooms · 2 bathrooms

Top rated rentals - DeSoto County

Gorgeous setting

Absolutely beautiful and well equipped property. They had coffee! Comfortable beds, plush towels, well equipped kitchen with ice. Board games to play if you've got the time. Take some bug repellent and enjoy the beauty of the outdoors. Pups loved being able to come along and had plenty of safe room to roam. Twenty minutes to anything you need or want, but a private setting where you can forget it all and just relax and enjoy your company. Only regret was not being able to stay longer. Thank you for opening your home for our quick weekend visit.

Angela M.

Stayed Sep 2023

Heart Attack Hangout

Our son-in-law had a heart attack scare. We rented the home and drove up from Florida. It was the perfect place for all of us to gather and be together.

Karen C.

Stayed Sep 2023

Relaxing

The property was very relaxing. The rooms were spacious. The fresh flowers were a very personal and caring gesture. We felt right at home. Whenever we went out, the kids would say, when are we going home, meaning the cozy house. We felt like we were home. The home was a very nice place to come back to. We all really enjoyed the home and the train. lol

Sharon D.

Stayed Aug 2023

Relax and be a Memphis tourist

This place is exactly as the pictures show - it's absolutely lovely. Perfectly decorated with everything you could need. The neighborhood is quiet and peaceful. The pool is extremely clean and a perfect temp for hot summer days. Its close proximity to tourist attractions in Memphis makes it an excellent choice! We got to site see and then relax by the pool. Cant compliment this place or the owner enough! Thank you for welcoming us into your home.

Annmarie K.

Stayed Aug 2023

Image of Beautiful House with Pool by Snowden Grove

Backyard Oasis

We brought our 4 month old to meet family in the area. This beautiful home was the perfect gathering place, especially the backyard. There were lots of baby items available to lounge in and play with. The hosts were very responsive and helpful. We really enjoyed our stay!

Brandy C.

Stayed Aug 2023

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Find the perfect vacation rental for your DeSoto County getaway

Experience the unique character of DeSoto County with a stay in a vacation home rental. This city has something for everyone. Take in top local attractions like Graceland and Beale Street. Are you looking for specific amenities for your getaway? Many of our vacation rentals feature full kitchens and laundry facilities.

Sightseeing in and around DeSoto County

Do you want to find things to do while you're in the area? Venture out of your cozy vacation rental and check out everything that makes DeSoto County a fun spot to vacation. These are some of the top attractions to put on your list, all within 30 miles (48.2 km) of the city center:

Tunica Queen Riverboat (21 mi / 33.7 km)
Memphis Zoo (22.6 mi / 36.3 km)
Southland Casino Racing (25.2 mi / 40.6 km)
Cherokee Valley Golf Club (12.1 mi / 19.5 km)
Tunica National Golf Course (17.3 mi / 27.8 km)
TPC Southwind (20.2 mi / 32.5 km)

Exploring the natural features in DeSoto County

Whether you're an active traveler or just want to spend some time taking in the scenery, DeSoto County is a great place to get out in nature. Here are a few of the area's most stunning features, all within 30 miles (48.2 km) of the city center: