Mayo vacation rentals

We found 34 vacation rentals — enter your dates for availability

Discover a selection of 19 homes and other vacation rentals in Mayo that are perfect for your trip. Whether you’re staying in a vacation home with family or friends, you'll find the amenities you need and want, such as WiFi and cable TV. Whatever you're looking for, you're sure to find a rental that has what everyone needs, including accessible or non-smoking choices.
  • Peace of mind

    Our Book with Confidence guarantee gives you 24/7 support
  • All the privacy of home

    Enjoy full kitchens, laundry, pools, yards and more
  • More for less

    More space, more privacy, more amenities — more value
  • A place for everyone

    We stand for diversity, inclusion and families everywhere.
    Learn more

Find out more about Mayo

Find out more about Mayo

Why visit Mayo

  1. Outdoor Activities: Mayo is a haven for hiking, fishing, and exploring scenic rivers and parks.
  2. Family-Friendly Atmosphere: The city offers numerous activities suitable for families and children.
  3. Charming Accommodations: Enjoy a variety of private vacation homes, cabins, and cottages for a cozy stay.
  4. Local Culture: Nearby Live Oak provides a taste of local culture and family-friendly attractions.
  5. Tranquil Environment: Experience the peaceful and welcoming spirit of this hidden gem in northern Florida.

Popular types of accommodation in Mayo

If you're exploring vacation rentals in Mayo, you're in for a treat! Our most popular accommodations include charming houses, cozy cabins, and delightful cottages. Whether you're seeking Mayo house rentals for a family getaway or ideal house rentals for a romantic retreat, we have options that cater to every traveler's needs. Enjoy transparency, savings, and reassurance as you find the perfect place to unwind in beautiful Mayo.

  • Houses: The top choice for visitors in Mayo, these homes provide spacious and comfortable accommodations perfect for families or groups.
  • Cabins: A popular option for those seeking a rustic experience, cabins offer a cozy retreat in the beautiful natural surroundings of Mayo.
  • Cottages: Charming and inviting, cottages are ideal for couples or small families wanting a quaint getaway.
  • Condos: Modern and convenient, condos provide a stylish stay with access to amenities and local attractions.
  • Caravan Parks: Great for adventurous travelers, caravan parks offer a unique outdoor experience with various facilities.**

Top attractions in and around Mayo

Mayo, Florida, is perfect for outdoor enthusiasts seeking adventure and scenic beauty. Visitors can explore the local rivers, national and state parks, and libraries, making it an ideal destination for families and nature lovers. Don't miss the opportunity to create a bucket list of experiences to fully enjoy all that Mayo has to offer, whether you're traveling solo or with loved ones.

  1. Lafayette Blue Springs State Park: Experience the breathtaking natural beauty of this state park, featuring crystal-clear springs ideal for swimming and kayaking. Enjoy hiking trails that offer a glimpse of Florida's lush landscapes and diverse wildlife.
  2. Suwannee River: A scenic river perfect for canoeing or fishing, the Suwannee River provides stunning views and a peaceful environment, allowing visitors to immerse themselves in the serene outdoors.
  3. Baker Park: This family-friendly urban park offers a mix of recreational facilities and green spaces, perfect for picnics, walking, or simply enjoying the vibrant city atmosphere.

What do I need to keep in mind when booking a vacation in Mayo

When planning your trip—whether you're traveling with a group, with family, bringing your pets, or seeking longer accommodations—it's important to prioritize your needs. Here are some helpful Vrbo booking tips to consider.

  • Traveling to Mayo with a group: Think about how many bedrooms you'll require, along with features like a full kitchen or outdoor areas for group gatherings. Thankfully, you can easily filter for these options and more on Vrbo.
  • Traveling to Mayo with young kids: Traveling with young kids can be quite a task. It’s important to prioritize their comfort and safety, along with ensuring access to suitable amenities like a private swimming pool. Additionally, it’s wise to think about how close you are to family-friendly attractions.
  • Taking your pets with you to Mayo: For many families, a vacation wouldn’t feel complete without their furry companions. If that resonates with you, explore Vrbo properties that welcome pets. Most of these pet-friendly accommodations come equipped with feeding bowls and beds, ensuring that every member of your family feels comfortable and at home.
  • Planning for a long term stay visiting Mayo: If you're in search of vacation rentals offering discounts for stays of a month or more, you've come to the right spot. By using the appropriate filters, you can effortlessly discover and save on monthly rentals. Don't forget to include amenities such as a parking space, a well-equipped kitchen, or a private pool in your search criteria as well.

Where to stay in and around Mayo

Mayo, Florida, offers a delightful escape for outdoor enthusiasts and families alike. Nestled in beautiful scenery, this charming city is perfect for adventure vacations. Explore nearby Live Oak for a taste of local culture and family-friendly activities. Whether you're hiking, fishing, or simply enjoying the tranquil atmosphere, Mayo promises memorable experiences. Don't miss the chance to discover the natural beauty and welcoming spirit of this hidden gem in northern Florida.

  • Branford: Located 16 miles from Mayo, Branford is a charming city that beckons outdoor enthusiasts and adventure seekers. The area is known for its stunning natural scenery, making it a prime spot for recreational activities. Visitors can engage in underwater sports or explore various adventure activities that the region has to offer. Key attractions include the breathtaking river views and the nearby national state park, where nature lovers can hike and enjoy the diverse wildlife. The tranquil water features in Branford provide perfect settings for relaxation and exploration.
  • O Brien: Just 14 miles away from Mayo, O Brien is another city that captures the essence of Florida’s outdoor lifestyle. Travelers flock to this area for its picturesque landscapes and thrilling adventures. Popular activities include recreational areas and various underwater sports, making it a fantastic choice for both relaxation and excitement. Visitors can also discover the local rivers and national state park, which serve as essential highlights for those looking to immerse themselves in nature's beauty. O Brien offers a perfect blend of adventure and stunning scenery.
  • Day: Nestled within the Mayo area, Day is a quaint village that draws visitors seeking beach experiences and outdoor fun. The village offers access to family-friendly beaches and a variety of recreational activities. With attractions such as local amusement parks and educational spots, Day is an ideal destination for families looking to make lasting memories. The picturesque beaches and serene rivers in the vicinity create an inviting atmosphere for relaxation and enjoyment, making it a must-visit during your vacation.

Best time to go to Mayo

If you're planning a trip to Mayo, it's a good idea to check both the weather and property rates. The warmest month is July. Peak season runs in March to April and September, while off-peak times, like February, August and December tend to have fewer bookings and better deals.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January53.4°F (11.9°C)Light RainMostly SunnyAverageSlightly Low
February57.9°F (14.4°C)Light RainMostly SunnySlightly LowSlightly Low
March62.8°F (17.1°C)Light RainMostly SunnySlightly HighAverage
April69.1°F (20.6°C)Light RainMostly SunnySlightly HighAverage
May75.4°F (24.1°C)Light RainMostly SunnyAverageAverage
June80.2°F (26.8°C)Light RainMostly SunnyAverageSlightly High
July81.5°F (27.5°C)Light RainMostly SunnyAverageSlightly High
August81.3°F (27.4°C)Light RainMostly SunnySlightly LowSlightly High
September77.9°F (25.5°C)Light RainMostly SunnySlightly HighAverage
October70.9°F (21.6°C)No Rain (Dry)Mostly SunnyAverageAverage
November61.9°F (16.6°C)Light RainMostly SunnyAverageAverage
December57.4°F (14.1°C)Light RainMostly SunnySlightly LowSlightly Low

Booking with Vrbo is a breeze

Are you hoping to save on your upcoming journey? Being flexible with your travel dates can really help, as prices tend to vary. Additionally, booking a longer stay often leads to significant savings. To discover the perfect Vrbo property that fits your budget, take advantage of our filters to sort by price, location, and type of vacation rental.

Unlock savings with One Key

Reserve a qualifying Vrbo for your group getaway and earn OneKeyCash™ on your reservation. Being the planner certainly has its perks! When you join our travel rewards program, One Key, you'll gain immediate access to member discounts and have the opportunity to earn and redeem OneKeyCash™ on eligible bookings. Sign up today and begin enjoying your savings!

Vrbo Trips: Planning as easy as it gets

Vrbo's Trip Board is designed to help you effortlessly plan your journeys, keep your travel arrangements organized, and review your bookings. Your saved or reserved properties are conveniently categorized into Potential, Upcoming, or Current Trips, making it easy for you to manage your travel plans. To discover more about Trip Boards, please visit: https://www.vrbo.com/en-us/trips.

**Based on Vrbo properties bookings.

Choose a vacation rental for your Mayo getaway

The parks and surrounding scenery provide a peaceful ambiance to your vacation home in Mayo. You'll find plenty to explore during your stay in the area. If you need more space to accommodate a family vacation or friends trip, rental homes often come with separate dining areas and spacious living rooms.

Activities and attractions in and around Mayo

Do you want to find attractions to visit in the city? Venture out of your vacation home and experience everything that makes Mayo a fun spot to vacation. Here are some of the most popular attractions to put on your list, all within 30 miles (48.2 km) of the city center:

  • Bob's River Place (23.4 mi / 37.6 km)
  • Taylor County Sports Complex (26.4 mi / 42.4 km)
  • One More Cast (29.6 mi / 47.7 km)

Exploring the natural landscape of Mayo

Whether you're looking for exciting outdoor activities or just want to spend some time taking in the scenery, Mayo is a great place to get outside. These are a few of the area's noteworthy natural features, all within 30 miles (48.2 km) of the city center:

  • Wes Skiles Peacock Springs State Park (5.9 mi / 9.5 km)
  • Suwannee River (16 mi / 25.8 km)
  • Steinhatchee Falls (23.4 mi / 37.7 km)
  • Suwannee River State Park (23.9 mi / 38.5 km)
  • Ichetucknee River (24.3 mi / 39.1 km)
  • Ichetucknee Springs State Park (25.1 mi / 40.4 km)

Frequently asked questions

What is the best area to stay in Mayo when booking a vacation rental?
When planning a vacation rental in Mayo, Florida, one of the best areas to consider is the vicinity around the Suwannee River. This region not only offers a serene natural setting but is also close to several attractions that enhance your stay. The Suwannee River is superb for kayaking, fishing, and enjoying scenic views, making it an ideal spot for outdoor enthusiasts.

Another attractive area is near the Lake City area, which is not too far from Mayo. This location provides easy access to the nearby Stephen Foster Folk Culture Center State Park, where visitors can explore the rich history of Florida's folk culture and enjoy the beautiful landscapes. The park often hosts events and festivals that celebrate local traditions, providing a unique cultural experience.

In terms of vacation rentals, both of these areas offer a variety of properties, suiting different preferences and budgets. You'll find cozy cabins, charming cottages, and spacious homes that allow you to immerse yourself in the natural beauty of North Florida.
How much does it cost to rent a vacation home in Mayo?
Prices for vacation rentals in Mayo vary based on factors like travel dates, length of stay, accommodation type, and location. Simply enter your trip details to explore a wide range of options—whether you're traveling solo, as a couple, with family, or in a group. Vrbo offers something for every taste and budget, from affordable rentals in Mayo to more spacious homes. To get the best value, book early and take advantage of Vrbo's free rewards program.
Are there any discounts for Mayo vacation house rentals?
You can find great discounts on house rentals in Mayo on Vrbo, including special rates on new listings and savings for weekly or monthly stays with top amenities such as a pool or parking. There are several discounts for Last minute bookings, and Early bird bookings too. The best part is, there's no need for a discount code—just enter your travel dates and apply the discount filters to view the top rates.
Where are the best areas for renting a beach house in Mayo?
For renting a beach house in Mayo, Florida, travelers should explore the areas along the Gulf Coast, particularly near the Big Bend region. The stretch of coastline around the Suwannee River State Park offers access to pristine beaches and opportunities for outdoor activities. Many rental properties in this area feature amenities such as private docks for fishing, screened porches for enjoying the warm evenings, and well-equipped kitchens to prepare fresh seafood.

Additionally, the nearby town of Steinhatchee provides charming rental options that are close to the water, often boasting features like spacious decks, kayaks for exploring the local waterways, and direct access to scenic river views. This area is particularly popular for those looking to experience the local wildlife and enjoy boating or fishing excursions.

For those interested in a more secluded experience, consider properties along the shoreline of the Lower Suwannee National Wildlife Refuge, where you can find vacation homes surrounded by nature. These accommodations typically include features such as outdoor grills, fire pits for evening gatherings, and proximity to hiking trails that lead to stunning natural landscapes.
What is the most popular type of vacation rental accomodation in Mayo?
In Mayo, vacation houses are the most popular type of rental, with about 17 available throughout the area. These houses often provide a spacious layout, featuring multiple bedrooms, fully equipped kitchens, and comfortable living areas for families or groups. Many of these properties are situated near natural points of interest, allowing easy access to outdoor activities like fishing and hiking.

In addition to vacation houses, several cabins, apartments, and mobile homes are also offered, suiting different preferences and needs. Cabins provide a rustic experience, often located in tranquil spots surrounded by nature. Apartments are suitable for smaller groups or couples, usually equipped with essential amenities for a convenient stay.
Are there any family house rentals in Mayo?
In Mayo, Florida, there are some available family-friendly house rentals, with around 21 options throughout the area. This charming locale, located near the scenic Suwannee River, provides an inviting backdrop for family gatherings. Many of these homes feature spacious living areas, fully equipped kitchens for preparing family meals, and outdoor spaces great for children to enjoy.

Visitors can find properties that include amenities such as air conditioning and Wi-Fi, ensuring a comfortable stay for everyone. The natural beauty of the surrounding area offers opportunities for outdoor activities, including fishing and kayaking along the river, making Mayo an appealing destination for families seeking both relaxation and adventure. See all family-friendly rentals in Mayo.
Can I rent a vacation home with a pool or hot tub in Mayo?
In Mayo, Florida, there are several vacation homes available for rent that feature pools and hot tubs, making it a great destination for relaxation and leisure. This small town, located along the Suwannee River, offers a serene environment superb for family gatherings or peaceful retreats. Many of the rental properties come equipped with inviting outdoor areas that include private pools, hot tubs, and spacious patios for sunbathing or barbecuing. Inside, travelers can expect amenities such as fully equipped kitchens, comfortable living spaces, and multiple bedrooms, ensuring a comfortable stay for all guests. The natural beauty of the surrounding area adds to the appeal, with opportunities for fishing, kayaking, and hiking nearby.
Can I find long-stay vacation rentals in Mayo?
A long-stay vacation rental in Mayo is the best way to experience local living. Plus, you can make the most of long-stay discounts. For month-long stays, save an average of 19%, and for week-long bookings you can save an average of 10%.* Long-stay discounts are applied automatically when you enter your vacation dates into the search tool, or you can use the "Weekly stay" and "Monthly stay" filters in your search.

*Based on analysis of Vrbo booking and occupancy data for 2024 stays.
Are there pet-friendly house rentals in Mayo?
In Mayo, Florida, there are several pet-friendly house rentals available, providing a welcoming environment for travelers with furry companions. Many of these vacation homes offer spacious layouts and outdoor areas, allowing pets to enjoy the fresh air. Amenities often include fully equipped kitchens, private yards, and sometimes even access to nearby nature trails.

Mayo is located in a scenic region known for its natural beauty, with opportunities for outdoor activities such as hiking and fishing in the nearby Suwannee River and the surrounding forests. See all pet-friendly rentals in Mayo.
Are there any remote work vacation rentals in Mayo?
In Mayo, Florida, there are several vacation rentals available that cater to remote workers, with around 21 options to choose from. This charming town is located in a peaceful setting, making it an excellent choice for those looking to balance work and relaxation. Many properties offer dedicated workspaces, high-speed internet, and comfortable accommodations to facilitate productivity.

Travelers can expect amenities such as fully equipped kitchens, outdoor seating areas, and proximity to natural attractions, which provide opportunities for outdoor activities during breaks. Mayo's serene environment, combined with access to local parks and the nearby Suwannee River, enhances the remote work experience, allowing guests to unwind in nature after a productive day. To help narrow your search, insert your dates and apply the "WiFi" filter on Vrbo.
Are there any Mayo vacation rentals with parking?
Vrbo offers a wide selection of vacation rentals in Mayo with parking available—perfect for families or travelers who value the convenience of having a car during their stay. To easily find these properties, simply enter your travel details on Vrbo and use the "Parking available" filter under the amenities section. This makes it quick and easy to browse listings that suit your needs, whether you're planning a short city break or a longer stay.
What are popular rental amenities in Mayo?
In Mayo, vacation rentals typically offer a range of amenities that cater to travelers' needs. Most properties come equipped with WiFi, allowing guests to stay connected during their stay. Fitness facilities are also available in some rentals, providing options for those looking to maintain their workout routines. Many rentals are pet-friendly, permitting guests to bring their furry companions along, and service animals are accommodated as well. Additionally, having a kitchen is a common feature, enabling guests to prepare their own meals, which is especially convenient for families or longer stays.
When is the best time to visit Mayo for a vacation rental?
March is the most popular time to visit Mayo, Florida, as the region comes alive with spring blooms and pleasant weather. This month marks the beginning of the peak season, which extends through May, attracting travelers who seek outdoor adventures and a vibrant atmosphere. With temperatures typically ranging from the low 50s to the high 70s Fahrenheit, the climate is superb for exploring the beautiful natural surroundings, including the nearby scenic rivers and lush landscapes.

During this peak season, visitors can enjoy various activities such as hiking, fishing, and kayaking, all while enjoying the warm sunshine. The local community also hosts events and festivals that showcase the charm of Mayo, making it an ideal time for those looking to immerse themselves in the culture and beauty of the area.

For those considering a more budget-friendly option, December is a fantastic time to visit Mayo. During this time, the mild winter temperatures provide a comfortable setting for tranquil outdoor experiences, superb for leisurely walks or enjoying the serene beauty of the local parks.

Ultimately, the best time to book a vacation rental in Mayo depends on your preference for lively seasonal activities or a more peaceful getaway.
How early should I book a Mayo vacation rental?
Book your Mayo vacation rental at least two months before you travel for the best selection of properties.* Plus, you'll typically find that the earlier you book your vacation rental, the better the price.

*Based on analysis of Vrbo booking and occupancy data for 2024 stays.
What are the top attractions in Mayo?
In Mayo, Florida, visitors can explore several attractions that highlight the area's natural beauty and outdoor activities. The Suwannee River, which flows nearby, offers opportunities for fishing, kayaking, and boating. Vacation rentals near the river provide easy access to scenic views and tranquil waters.

The nearby Ichetucknee Springs State Park is a popular destination for tubing and swimming in its clear, spring-fed waters, and offers hiking trails for those looking to immerse themselves in nature. Properties in the surrounding area often feature rustic charm and proximity to these natural attractions, making them ideal for outdoor enthusiasts.

Additionally, the town of Mayo itself has local shops and eateries that reflect the small-town charm of North Florida, providing a great experience for visitors.
Can I change or cancel my Mayo home rental booking on Vrbo?
To find Mayo vacation rentals with free cancellation, just use Vrbo's handy "Free cancellation" search filter. We get that plans can change, so it's easy to filter properties that give you flexibility. If you need to make changes to an existing booking, drop your host a message. Go to "My Trips" in your account, click "Change or Cancel" and then "Message Host". Vrbo rentals give you the privacy of having the entire place to yourself, and for extra flexibility, some travelers can choose to pay over time with Affirm. Whether you're adjusting your plans or looking for flexible payment options, Vrbo makes it easy to book with confidence.
Why should I join Vrbo as a host?
Joining Vrbo as a host opens the door to a global community of travelers seeking unique stays, giving you the opportunity to earn income from your property on your terms. With user-friendly tools, dedicated support, and exposure on major travel sites, Vrbo makes it easy to list, manage, and succeed. Whether it's a cozy flat or a countryside retreat, you can turn your space into a standout destination—become a host and let Vrbo handle the heavy lifting to help you thrive.
Are all fees included in the Mayo vacation rental prices shown on Vrbo?
Vrbo provides upfront pricing from the moment you start your search. There are no hidden fees added during the check-out process. This allows you to compare properties with ease and plan your trip with confidence.

More Vacation Rentals ideas

People also search for