Panacea vacation rentals

We found 325 vacation rentals — enter your dates for availability

Select from 157 homes, 27 cottages, and other vacation rentals in Panacea to find one that's perfect for your trip. Vacation homes offer the amenities you expect for your stay with friends, family, or just your pet, such as WiFi and a pool. At the end of the day, you're sure to find a rental to meet everyone's needs, including a place that is accessible or non-smoking.

Vacation rentals with weekly discounts - Panacea

Showing deals for:Nov 14 - Nov 21
  • Peace of mind

    Our Book with Confidence guarantee gives you 24/7 support
  • All the privacy of home

    Enjoy full kitchens, laundry, pools, yards and more
  • More for less

    More space, more privacy, more amenities — more value
  • A place for everyone

    We stand for diversity, inclusion and families everywhere.
    Learn more

Find out more about Panacea

Find out more about Panacea

Why visit Panacea

  1. Stunning Beaches: Enjoy the pristine shores of Panacea, perfect for relaxation and sunbathing.
  2. Outdoor Adventures: Explore nearby state parks and scenic islands for hiking, fishing, and kayaking.
  3. Family-Friendly Atmosphere: Experience a welcoming vibe with various recreational options for all ages.
  4. Charming Accommodations: Choose from private vacation homes, cozy condos, and delightful cottages for a comfortable stay.
  5. Natural Beauty: Immerse yourself in the breathtaking landscapes that define this coastal gem.

Popular types of accommodation in Panacea

If you're planning a getaway in Panacea, you're in for a treat! Our most popular types of vacation rentals include Houses, cozy Condos, and charming Cottages. With Panacea vacation rentals, you can enjoy comfort and convenience while exploring the area. Discover the perfect rental home for your next adventure and experience the savings, transparency, and reassurance we offer in every booking.

  • Houses: These are the top choice for visitors seeking spacious and comfortable accommodations, ideal for families or groups looking to enjoy a home-like atmosphere during their stay in Panacea.
  • Condos: A popular option for those looking for modern amenities and community facilities, condos offer a blend of comfort and convenience.
  • Cottages: Charming and often located near the water, cottages provide a cozy getaway experience.
  • Apartments: These rentals are perfect for travelers who prefer a more urban lifestyle, featuring self-contained living spaces.
  • Caravan Parks: A unique option for outdoor enthusiasts, caravan parks offer a blend of camping and comfort in scenic settings.**

Top attractions in Panacea

Panacea, Florida, is a perfect destination for beach and outdoor enthusiasts looking to enjoy stunning scenery. The area is known for its beautiful beaches, nearby state parks, and scenic islands, offering a variety of activities for travelers. Whether you're seeking relaxation by the shore or adventurous explorations in nature, Panacea has something for everyone. Don't miss the opportunity to discover the local points of interest and immerse yourself in the natural beauty of this charming coastal town.

  1. Alligator Point Beach: A tranquil stretch of sand with a laid-back atmosphere, perfect for sunbathing and swimming. Enjoy beautiful sunsets and the gentle sound of waves, making it an ideal spot for relaxation.
  2. Bald Point State Park: Experience outdoor adventure with hiking trails, birdwatching, and stunning views of the Gulf. This park is a haven for nature lovers, offering a diverse ecosystem and scenic landscapes.
  3. USS Mohawk CGC Veterans Memorial Reef: A unique underwater memorial and artificial reef, honoring veterans. Snorkel or dive among marine life while appreciating the cultural significance of this historic site.

Things to do recommended for families

Families visiting Panacea can unwind at Woolley Park, explore Myron B Hodge City Park just 6 miles away, or enjoy the scenic beauty of Morrison Hammock Scenic Area 7 miles from town. Each spot offers a tranquil atmosphere perfect for relaxation and bonding together.

What do I need to keep in mind when booking a vacation in Panacea

When traveling with a group, family, or pets, or if you're planning an extended stay, it's important to filter your options based on your specific needs. Here are some helpful tips for booking on Vrbo.

  • Traveling to Panacea with a group: Think about how many bedrooms you'll require, along with features like a complete kitchen or outdoor space for group gatherings. Luckily, you can easily filter for these options and many more on Vrbo.
  • Traveling to Panacea with young kids: Traveling with little ones can be demanding. It’s important to prioritize their comfort and safety, along with amenities suited for their age, like a private swimming pool. Additionally, thinking about how close you are to family-friendly attractions is wise.
  • Taking your pets with you to Panacea: For many families, a vacation isn’t truly enjoyable unless their furry companion is along for the ride. If that resonates with you, explore Vrbo listings that welcome pets. Many of these pet-friendly accommodations come equipped with feeding bowls and beds, ensuring that all members of your family feel comfortable and at home.
  • Planning for a long term stay visiting Panacea: If you're in search of vacation rentals that offer discounts for stays of a month or more, you've come to the perfect spot. By using the appropriate filters, you can effortlessly discover and save on monthly rental options. Don't forget to include features like a parking space, a well-equipped kitchen, or a private pool in your search criteria as well.

Where to stay in Panacea

Panacea, Florida, offers a perfect coastal getaway for tourists seeking a blend of relaxation and outdoor adventures. Nestled in the scenic Florida Panhandle, this charming city provides easy beach access and a serene atmosphere. Families can enjoy the friendly vibe and recreational options nearby, making it an ideal vacation home destination. Explore the beautiful surroundings, indulge in water activities, or simply unwind on the beach for a memorable escape in Panacea.

  • Alligator Point: Nestled along the Gulf Coast, Alligator Point is a charming village that offers a serene escape for beach lovers and outdoor enthusiasts. Known for its stunning beaches and scenic landscapes, visitors can enjoy various recreational activities such as fishing, kayaking, and beachcombing. The nearby Alligator Point Golf Course provides a perfect blend of relaxation and sport. Local attractions include the pristine beaches and the nearby national state park, where you can explore diverse wetlands and enjoy nature trails. With its tranquil atmosphere and beautiful scenery, Alligator Point is an ideal destination for a peaceful getaway.
  • Saint Teresa: Located close to Panacea, Saint Teresa is a picturesque village that attracts visitors with its beautiful beaches and outdoor recreational options. This charming community offers a variety of activities, including golfing and nature exploration, making it a great spot for families and outdoor enthusiasts alike. With its proximity to the national state park and lush wetlands, visitors can experience the area's stunning natural beauty firsthand. Saint Teresa is perfect for those looking to relax on the beach, indulge in water sports, and immerse themselves in the serene coastal environment.
  • Ochlockonee Bay: A hidden gem along the coast, Ochlockonee Bay is a village that offers a unique blend of adventure and relaxation. With its beautiful bay views and abundant outdoor activities, visitors can engage in fishing, boating, and exploring the surrounding natural parks. This area is perfect for nature lovers, with nearby wetlands and picturesque landscapes providing ample opportunities for wildlife observation and photography. The local recreational areas and resorts enhance the travel experience, making Ochlockonee Bay an excellent choice for those seeking both adventure and tranquility.

Best time to go to Panacea

If you're planning a trip to Panacea, it's a good idea to check both the weather and property rates. The warmest months are July and August. Peak season runs in April and June to July, while off-peak times, like October to December tend to have fewer bookings and better deals.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January53.6°F (12.0°C)Light RainMostly SunnyAverageSlightly Low
February57.6°F (14.2°C)Light RainMostly SunnyAverageSlightly Low
March62.4°F (16.9°C)Light RainMostly SunnyAverageSlightly Low
April68.2°F (20.1°C)Light RainMostly SunnyModerately HighAverage
May74.8°F (23.8°C)Light RainMostly SunnyAverageSlightly High
June80.4°F (26.9°C)Moderate RainMostly SunnyModerately HighSlightly High
July81.7°F (27.6°C)Moderate RainMostly SunnyModerately HighSlightly High
August81.7°F (27.6°C)Moderate RainMostly SunnyAverageAverage
September78.4°F (25.8°C)Light RainMostly SunnyAverageAverage
October71.1°F (21.7°C)Light RainMostly SunnyModerately LowAverage
November61.9°F (16.6°C)Light RainMostly SunnyModerately LowAverage
December57.6°F (14.2°C)Light RainMostly SunnyModerately LowAverage

Booking with Vrbo is a breeze

Are you hoping to cut costs on your upcoming journey? One effective strategy is to be flexible with your travel dates, as prices can vary significantly. Additionally, opting for a longer stay often leads to substantial savings. To discover the perfect Vrbo property that fits your budget, take advantage of our filters to sort by price, location, and type of vacation rental. We're here to help you find the best options!

Unlock savings with One Key

Reserve a qualifying Vrbo for your group getaway and receive OneKeyCash™ on your entire booking. Being the planner definitely has its perks! By becoming a member of our travel rewards program, One Key, you’ll gain access to exclusive discounts and earn OneKeyCash™ on eligible bookings. Join today and start enjoying your savings!

Vrbo Trips: Planning as easy as it gets

Vrbo’s Trip Board offers a user-friendly platform to plan your upcoming adventures, pick up right where you left off, or organize your travel itinerary. You can easily find your saved or booked properties sorted into categories like Potential, Upcoming, or Current Trips. To begin exploring the benefits of Trip Boards, head over to: https://www.vrbo.com/en-ca/trips.

**Based on Vrbo properties bookings.

Why people love visiting tranquil Panacea

The beaches and wildlife provide a pleasant backdrop to your vacation home in Panacea. Well known for its dolphin watching, seafood restaurants and fishing, this relaxing city won't disappoint. With a vacation rental, you get a home away from home. Many rentals offer full kitchens and outdoor grills for some home cooking.

Activities and attractions in Panacea

Are you hoping to find attractions to see during your stay? You'll be sure to enjoy Panacea for its dolphin viewing opportunities and fishing. Although it can be tempting to stay in your comfortable vacation rental, you'll want to check out everything that makes Panacea a one-of-a-kind vacation spot. Here are some of the major attractions to see, all within 30 miles (48.2 km) of the city center:

  • St. James Bay Golf Club (13 mi / 21 km)
  • Wildwood Golf Club (7.3 mi / 11.7 km)
  • Gulf Specimen Public Aquarum (0.8 mi / 1.2 km)

Exploring the natural landscape of Panacea

Whether you're an outdoor enthusiast or just want to spend some time taking in the scenery, Panacea is a great place to get out in nature. These are a few of the area's noteworthy features, all within 30 miles (48.2 km) of the city center:

  • Mashes Sand Beach (5.1 mi / 8.2 km)
  • Shell Point Beach (6.7 mi / 10.8 km)
  • Wilson Beach (7.4 mi / 11.9 km)
  • Alligator Point Beach (8.3 mi / 13.3 km)
  • Bald Point State Park (9 mi / 14.6 km)
  • Apalachicola National Forest (16.3 mi / 26.2 km)

Seasonal weather averages in Panacea

If warm-weather activities are high on your list, July, August, June and September are the hottest months to visit, when temperatures average 81°F.

How to get to and around Panacea

The nearest airport is in Tallahassee Intl. Airport (TLH), located 25.5 mi (41.1 km) from the city center.

Frequently asked questions

What is the best area to stay in Panacea when booking a vacation rental?
Alligator Point is among the most sought-after neighborhoods to book a vacation property in Panacea. Stay here and delight in the comfort and privacy that comes with having a place to yourself.
What is the most popular type of vacation rental accommodation in Panacea?
Condos are the most popular type of vacation rental in Panacea, according to our data. Even if you've got something else in mind, Vrbo has vacation homes in a variety of sizes and shapes. Filter our options to find your ideal match.
How much does it cost to rent a vacation rental in Panacea?
The average price for a vacation home in Panacea is based on several factors, such as season, property type and length of stay. Whether you prefer a villa with space for extended family or a cozy cabin for you and your other half, just add your travel dates to discover stays with amazing value.
How much does it cost to rent a beach house in Panacea?
Prices for beach houses in Panacea can differ depending on the size and type of the property and when you plan to travel. All you have to do is enter your travel dates into Vrbo and how many guests to view your vacation rental options and prices. From there you can use our filters to narrow your search by ratings, nearby activities and more.
Are there pet-friendly vacation rentals in Panacea?
Pack a travel bag and a bone for your canine companion because Panacea has 101 vacation homes that roll out the welcome mat to doggie guests. Let your furriest friend enjoy the family fun at one of our pet-friendly vacation rentals on Vrbo. Simply enter your destination and travel dates, then check the "Pets allowed" filter box.
Can I rent a house with a pool in Panacea?
Pack your swimwear and goggles, because there are 15 houses with a private pool in Panacea. Unwind at one of these sought-after vacation homes and you'll enjoy pool days every day. Simply enter your dates into Vrbo, then use the "pool" filter to find the perfect place for a splashing good time!
What are popular rental amenities in Panacea?
When it comes to rental amenities that guests look for in Panacea, an electric car charging station, a swimming pool and tennis rank the highest. With Vrbo vacation homes, you'll discover options to fit your taste and style, whether you're taking a trip with friends, relatives or even pets.
Are there large group vacation rentals in Panacea?
Panacea has five vacation rentals that can cater to 10 or more guests. These properties come with enough space to share good times with your favorite people.
Are there vacation rentals in Panacea that welcome kids?
With 100 family-friendly vacation properties available in Panacea, now is an awesome time to introduce your kids to the pleasures of travel. Just check our "Properties good for families" filter to discover stays packed with amenities perfect for traveling families, such as dining rooms, backyards, entertainment areas and hot tubs.
What are the top attractions for families in Panacea?
Keep the kids occupied at these popular family-friendly attractions in Panacea:

  • Alligator Point Beach
  • Bald Point State Park
  • Mashes Sand Beach

Are there one-bedroom vacation rentals in Panacea?
You'll find three one-bedroom properties in Panacea to choose from. A one-bedroom vacation property is an excellent option if it's only you and your partner or if you're vacationing alone. Add in more space, convenience and privacy compared to a standard hotel, and you're sure to have a trip to remember.
Can I find two-bedroom vacation rentals in Panacea?
Panacea has six two-bedroom vacation rentals for you to pick from. Find a vacation home with all the comfort and privacy you want at a price you'll love on Vrbo.
Are there vacation rentals with WiFi in Panacea?
You'll have a choice of 55 vacation rentals with WiFi in Panacea. If you'd like to disconnect from daily life during your trip, but still need to be connected to the web, these getaways are just what you need. Narrow your search by applying the WiFi filter on Vrbo.
How can I find vacation rentals with air conditioning in Panacea?
Panacea has 100 vacation rentals where you can chill out in air-conditioned comfort. To find a property on Vrbo that provides this amenity, enter your dates of travel and use the handy filter tool to select the "air conditioning" box.
How old do you have to be to rent a vacation rental in Panacea?
The minimum age permitted can differ between properties on Vrbo, so look at the rules of the vacation rental in Panacea you want. But normally, it's 16, 18 or 21.
How long can I rent a vacation rental in Panacea for?
It really depends on the Panacea property. To look over a list of options offering extended stays, simply enter your dates and guest number into Vrbo. You can look forward to having the whole property to yourself, along with amenities such as a fully-equipped kitchen, air conditioning and outdoor spaces where the kids can run around and play. Keep your eyes peeled for any long-term stays that offer discounted weekly or monthly prices.
Does Vrbo offer discounts for vacation homes in Panacea?
In Panacea, you'll find some great bargains and discounts for weekly and monthly discounts on vacation rentals, as well as newly listed homes on Vrbo. Whether you're after a mini vacay or a much longer stay, we have a host of options that'll suit your style.