San Diego house rentals

Choose one of our 4,773 vacation home rentals in San Diego and you’ll have an ideal base for your next adventure. Civic Core, Downtown San Diego and Gaslamp Quarter are some of the city’s most popular areas.

Exactly where you stay, when you decide to travel and the length of your trip will determine how much you pay for a vacation home rental in San Diego. Enter your travel dates on Vrbo to easily compare options and then book the right one for you.

Most Vrbo guests prefer to stay in a vacation home rental in San Diego during March. At this time of year, temperatures range between 53ºF (12ºC) and 64ºF (18ºC) in this part of San Diego County.

Whether it’s the sea, a river or the neon city lights, a vacation home rental is always better with views. Wherever you prefer to stay in San Diego, Vrbo will help you find a house with postcard-worthy outlooks. Simply click on the “Popular” button at the top of the page, then check the filters to fine-tune your search.

Explore our weekend rentals and prepare for a memorable couple of days away. Our top tips for booking your ideal house in San Diego? Stay flexible when searching and modify your travel dates until you find the vacation home rental that fits your style.

Spend your next adventure with your furry companion at one of our 171 pet-friendly vacation home rentals in San Diego. These stays come with perks that’ll make your pup feel at home, including a backyard to play in. Just check the “Pets allowed” filter to find a house that has room for every beloved member of your family.

Planning an unforgettable trip to San Diego means discovering fun things that the whole family will love. San Diego Zoo, Balboa Park and La Jolla Cove are just two of the options here. And our vacation home rentals are a terrific base for your sightseeing adventures.

First-rate customer support from the second you book until after your stay is one of the many reasons to choose us for your upcoming vacation home rental. We also have properties that go beyond the usual hotel room — think houses in incredible locations, whether that’s by the ocean or up in the mountains. Plus, thanks to our One Key™ rewards program, you can collect and redeem OneKeyCash™* on eligible bookings with Vrbo, Expedia and Hotels.com. And with flexible cancellation policies and benefits like damage deposit protection, we ensure peace of mind. *OneKeyCash disclaimer - OneKeyCash is not redeemable for cash and can only be used on Hotels.com, Expedia and Vrbo.